In organic chemistry, nitrosamines (or more formally N-nitrosamines) are organic compounds with the chemical structure R2N−N=O, where R is usually an...

Tobacco-specific nitrosamines (TSNAs) comprise one of the most important groups of carcinogens in tobacco products, particularly cigarettes (traditional...

drugs) contain nitrosamine impurities. Health Canada also reported nitrosamine impurities. The FDA issued revised guidelines about nitrosamine impurities...

Nicotine-derived nitrosamine ketone (NNK) is one of the key tobacco-specific nitrosamines derived from nicotine. It plays an important role in carcinogenesis...

presence of nitrosamine impurities and asked them to review all chemical and biological human medicines for the presence of nitrosamines and to test the...

the possible presence of nitrosamines and to test the products at risk. The FDA issued revised guidelines about nitrosamine impurities in September 2024...

formula (CH3)2NNO. It is one of the simplest members of a large class of nitrosamines. It is a volatile yellow oil. NDMA has attracted wide attention as being...

effect of nitrosamines on DNA; however, little has been done to control for other possible causes in the epidemiological results. Nitrosamines, formed in...

In biochemistry, nitrosamines are a class of compounds that can form during food digestion. The presence of their precursors, nitrites, in cured meats...

consumption. Opponents of snus sales maintain, nevertheless, that even the low nitrosamine levels in snus cannot be completely risk-free, but snus proponents point...

the formation of nitrosamines but has no effect on S-Nitrosothiols and nitrosyl-heme. Vitamin E (tocopherol) also reduces nitrosamine levels. Bacon fried...

S-nitroso compounds (nitrosothiols; RS−N=O), N-nitroso compounds (e.g., nitrosamines, RN(−R’)−N=O), and O-nitroso compounds (alkyl nitrites; RO−N=O). Nitroso...

different types of products (e.g., low nitrosamine Swedish-type snus versus other smokeless tobacco with high nitrosamine levels) and producing regions. There...

one API producer. Since then, FDA has determined that other types of nitrosamine compounds, e.g., N-Nitrosodiethylamine (NDEA), are present at unacceptable...

implicated as the causative agents in the carcinogens. Specifically, nitrosamines are thought to undergo metabolic activation to produce alkanediazonium...

risk is likely related to the presence of nitrosamines in processed meat products like pancetta. Nitrosamines are carcinogenic compounds formed by the...

the anus, usually in or with stool) or hematuria (blood in the urine). Nitrosamine formation in beetroot juice can reliably be prevented by adding ascorbic...

ongoing investigation into ARB drug products; reports on finding of a new nitrosamine impurity in certain lots of losartan and product recall" (Press release)...

(vitamin E) to further inhibit nitrosamine production. α-Tocopherol, ascorbic acid, and erythorbic acid all inhibit nitrosamine production by their oxidation-reduction...

rearrangement reaction in which an aromatic N-nitroso (−N=O) or secondary nitrosamine (>N−N=O) converts to a carbon nitroso compound: This organic reaction...

by reducing the time needed for the meat to be cooked at high heat. Nitrosamines are found in some food, and may be produced by some cooking processes...

sulfonamides n-Butyl nitrite and ammonia convert phenylhydroxylamine to its nitrosamine derivative cupferron. Likewise pyrrolidine is a substrate for ethyl nitrite...

metformin medicines manufactured outside the United States might contain a nitrosamine impurity called N-nitrosodimethylamine (NDMA), classified as a probable...

nitrites. Nitrite salts can react with secondary amines to produce N-nitrosamines, which are suspected of causing stomach cancer. The World Health Organization...

known carcinogens have been identified in cannabis smoke, including; nitrosamines, reactive aldehydes, and polycyclic aromatic hydrocarbons, including...

August 2020, the U.S. Food and Drug Administration (FDA) became aware of nitrosamine impurities in certain samples of rifampin. The FDA and manufacturers...

mouth. Nitrites lead to the formation of carcinogenic nitrosamines. The production of nitrosamines may be inhibited by the use of the antioxidants vitamin...

S-Nitrosoglutathione (GSNO, SNOG) SNO-t-PA SNO-vWF; N-Nitroso compounds (e.g., nitrosamines): SIN-1A Nitrosyl compounds: Metal nitrosyl complexes: Roussin's black...

August 2020, the U.S. Food and Drug Administration (FDA) became aware of nitrosamine impurities in certain samples of rifapentine. The FDA and manufacturers...

effects are presumed to be caused by nitrates and nitrites, as well as nitrosamines which are formed by nitrites reacting with meat. These risks are generally...