• Thumbnail for Nucleosome
    A nucleosome is the basic structural unit of DNA packaging in eukaryotes. The structure of a nucleosome consists of a segment of DNA wound around eight...
    56 KB (6,714 words) - 23:28, 19 May 2024
  • Thumbnail for Histone octamer
    histone octamer is the eight-protein complex found at the center of a nucleosome core particle. It consists of two copies of each of the four core histone...
    19 KB (2,478 words) - 12:04, 3 August 2024
  • The nucleosome repeat length, (NRL) is the average distance between the centers of neighboring nucleosomes. NRL is an important physical chromatin property...
    5 KB (590 words) - 07:06, 3 December 2023
  • Nucleosome Remodeling Factor (NURF) is an ATP-dependent chromatin remodeling complex first discovered in Drosophila melanogaster (fruit fly) that catalyzes...
    5 KB (569 words) - 16:35, 7 May 2024
  • forming nucleosomes and the so-called beads on a string structure (euchromatin). Multiple histones wrap into a 30-nanometer fiber consisting of nucleosome arrays...
    53 KB (5,924 words) - 18:46, 4 August 2024
  • Thumbnail for Epigenetics
    involve positive feedback where modified nucleosomes recruit enzymes that similarly modify nearby nucleosomes. A simplified stochastic model for this type...
    161 KB (18,344 words) - 08:31, 28 July 2024
  • Thumbnail for S phase
    strand disrupts parental nucleosome octamers, resulting in the release of H3-H4 and H2A-H2B subunits. Reassembly of nucleosomes behind the replication fork...
    15 KB (1,681 words) - 15:45, 29 October 2023
  • Thumbnail for Chromatosome
    molecular biology, a chromatosome is a result of histone H1 binding to a nucleosome, which contains a histone octamer and DNA. The chromatosome contains 166...
    2 KB (223 words) - 19:05, 2 December 2023
  • linker DNA is double-stranded DNA (38-53 base pairs long) in between two nucleosome cores that, in association with histone H1, holds the cores together....
    1 KB (191 words) - 10:43, 30 December 2022
  • Nucleosome Positioning Region Database (NPRD) is a database of nucleosome formation sites (NFSs).[when?] International Society for Computational Biology...
    1 KB (83 words) - 01:22, 30 April 2022
  • In the field of molecular biology, the Mi-2/NuRD (Nucleosome Remodeling Deacetylase) complex, is a group of associated proteins with both ATP-dependent...
    9 KB (1,064 words) - 00:25, 17 May 2024
  • Thumbnail for NAP1L3
    Nucleosome assembly protein 1 like 3 is a protein that in humans is encoded by the NAP1L3 gene. This gene is intronless and encodes a member of the nucleosome...
    744 bytes (133 words) - 09:05, 27 March 2022
  • wrapping of DNA around proteins called histones in order to form condensed nucleosomes. The double helix was discovered in 1953 by James Watson and Francis...
    7 KB (857 words) - 10:18, 3 January 2023
  • Thumbnail for SWI/SNF
    subfamily provides crucial nucleosome rearrangement, which is seen as ejection and/or sliding. The movement of nucleosomes provides easier access to the...
    38 KB (3,947 words) - 18:18, 28 June 2024
  • Thumbnail for Cellular differentiation
    nucleosome is covering a given genomic binding site or not. This can be determined using a chromatin immunoprecipitation (ChIP) assay. DNA-nucleosome...
    50 KB (6,033 words) - 03:30, 25 July 2024
  • Thumbnail for Histone
    spools around which DNA winds to create structural units called nucleosomes. Nucleosomes in turn are wrapped into 30-nanometer fibers that form tightly...
    84 KB (9,582 words) - 12:27, 10 August 2024
  • Thumbnail for Histone H1
    make up the nucleosome "bead". Instead, it sits on top of the structure, keeping in place the DNA that has wrapped around the nucleosome. H1 is present...
    20 KB (2,228 words) - 08:59, 26 March 2024
  • Thumbnail for Chromosome
    organism. In most chromosomes, the very long thin DNA fibers are coated with nucleosome-forming packaging proteins; in eukaryotic cells the most important of...
    64 KB (6,538 words) - 18:22, 1 August 2024
  • Thumbnail for NOMe-seq
    Nucleosome Occupancy and Methylome Sequencing (NOMe-seq) is a genomics technique used to simultaneously detect nucleosome positioning and DNA methylation...
    17 KB (2,009 words) - 10:32, 7 March 2024
  • chromatin remodeling complexes which either move, eject or restructure nucleosomes. Besides actively regulating gene expression, dynamic remodeling of chromatin...
    50 KB (5,523 words) - 09:43, 3 December 2023
  • Thumbnail for Nucleosome assembly protein 1 like 5
    Nucleosome assembly protein 1 like 5 is a protein that in humans is encoded by the NAP1L5 gene. This gene encodes a protein that shares sequence similarity...
    923 bytes (157 words) - 22:36, 3 March 2023
  • Thumbnail for Endurance
    acetylations removed from H3K27 in nucleosomes located at the enhancers that control those genes (see Figure "A nucleosome with histone tails set for transcriptional...
    16 KB (1,520 words) - 20:27, 9 August 2024
  • Thumbnail for H2AFX
    histones H2A, H2B, H3 and H4, to form chromatin. H2AX contributes to nucleosome-formation, chromatin-remodeling and DNA repair, and is also used in vitro...
    22 KB (2,775 words) - 14:20, 8 August 2024
  • subfamily is the incorporation and removal of alternate histones in the nucleosome. In the presence of the H2A.Z histone, the INO80 subfamily of remodelers...
    5 KB (500 words) - 21:30, 5 September 2023
  • ISWI remodeling complexes place nucleosomes along segments of DNA at regular intervals. The placement of nucleosomes by ISWI protein complexes typically...
    4 KB (545 words) - 15:02, 31 July 2023
  • Thumbnail for DNA
    proteins are involved. The histones form a disk-shaped complex called a nucleosome, which contains two complete turns of double-stranded DNA wrapped around...
    166 KB (17,863 words) - 08:43, 15 August 2024
  • Thumbnail for Nucleoprotein
    acids (either DNA or RNA). Typical nucleoproteins include ribosomes, nucleosomes and viral nucleocapsid proteins. Nucleoproteins tend to be positively...
    18 KB (1,964 words) - 23:55, 6 March 2024
  • Thumbnail for Skeletal muscle
    tail) in a structure called a nucleosome and one segment of DNA is connected to an adjacent DNA segment on a nucleosome by linker DNA. When histone tails...
    120 KB (13,834 words) - 11:46, 13 June 2024
  • Thumbnail for MNase-seq
    molecular biological technique that was first pioneered in 2006 to measure nucleosome occupancy in the C. elegans genome, and was subsequently applied to the...
    39 KB (4,420 words) - 19:10, 15 May 2024
  • Thumbnail for H3F3A
    development. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each...
    12 KB (1,307 words) - 13:15, 31 August 2021