as PLCG1 and PLCgamma1, is a protein that in humans involved in cell growth, migration, apoptosis, and proliferation. It is encoded by the PLCG1 gene...
32 KB (3,828 words) - 21:52, 8 April 2024
"Human hepatocyte nuclear factor-4 (hHNF-4) gene maps to 20q12-q13.1 between PLCG1 and D20S17". Human Genetics. 99 (2): 233–6. doi:10.1007/s004390050345. PMID 9048927...
18 KB (2,230 words) - 04:52, 22 July 2024
with: CTNNB1, DLG4, Erbin, GRB2, HSP90AA1, IL6ST, MUC1, PICK1 and PIK3R2, PLCG1, and SHC1. SkBr3 Cell Line, over-expresses HER2 GRCh38: Ensembl release...
43 KB (4,651 words) - 05:18, 13 July 2024
INPPL1; ITK; JAK2; LCK; LCP2; LYN MATK; NCK1; NCK2 PIK3R1; PIK3R2; PIK3R3; PLCG1; PLCG2; PTK6; PTPN11; PTPN6; RASA1 SH2B1; SH2B2; SH2B3; SH2D1A; SH2D1B;...
13 KB (1,341 words) - 04:09, 6 March 2024
Diaph1, Diaph2, DgkQ, FlnA, KcnA2, Ktn1, Rtkn1, Rtkn2, Rhpn1, Rhpn2, Itpr1, PlcG1, PI-5-p5K, Pld1, Pkn1, Pkn2, Rock1, Rock2, PrkcA, Ppp1r12A Rac1 Sra1, IRSp53...
25 KB (3,198 words) - 05:03, 22 June 2024
role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon...
2 KB (293 words) - 01:13, 6 March 2022
to interact with: Brain-derived neurotrophic factor (BDNF), FYN, NCK2, PLCG1, Sequestosome 1, and SHC3. Trk receptor GRCh38: Ensembl release 89: ENSG00000148053...
40 KB (4,319 words) - 00:58, 9 June 2024
may have up to 30 PLC enzymes. beta: PLCB1, PLCB2, PLCB3, PLCB4 gamma: PLCG1, PLCG2 delta: PLCD1, PLCD3, PLCD4 epsilon: PLCE1 eta: PLCH1, PLCH2 zeta:...
25 KB (2,691 words) - 00:59, 17 April 2024
OSBPL8, OSBPL9, PHLDA2, PHLDA3, PHLDB1, PHLDB2, PHLPP, PIP3-E, PLCD1, PLCD4, PLCG1, PLCG2, PLCH1, PLCH2, PLCL1, PLCL2, PLD1, PLD2, PLEK, PLEK2, PLEKHA1, PLEKHA2...
14 KB (1,434 words) - 15:11, 10 June 2024
CRK, CTNNB1, DCN, EGF, GRB14, Grb2, JAK2, MUC1, NCK1, NCK2 PKC alpha, PLCG1, PLSCR1, PTPN1, PTPN11, PTPN6, PTPRK, SH2D3A, SH3KBP1, SHC1, SOS1, Src,...
60 KB (6,879 words) - 14:26, 16 July 2024
Also, it interacts with CBL, GRB2, LCK, NCK2, PIK3R1, PIK3R2, PIK3R3, PLCG1, SOCS1, and TNS2. GRCh38: Ensembl release 89: ENSG00000167601 – Ensembl...
19 KB (2,358 words) - 16:34, 16 July 2024
receptor kinase A, activity that stimulates the PI3K/AKT/mTOR, MAPK/ERK, and PLCG1 cell signaling pathways. Each of these pathways are known to promote the...
19 KB (2,198 words) - 20:40, 10 December 2023
interact with: CDC42, CRKL, EGFR, FGR, FYN, Grb2, ITK ITSN2, NCK1, PIK3R1, PLCG1, PSTPIP1, Src, TRIP10, and WIPF1. Wiskott–Aldrich syndrome-like cortactin...
21 KB (2,588 words) - 00:21, 5 February 2024
been identified for this gene. TUB (gene) has been shown to interact with PLCG1. GRCh38: Ensembl release 89: ENSG00000166402 – Ensembl, May 2017 GRCm38:...
6 KB (805 words) - 00:46, 26 October 2023
ARHGEF12, ARHGEF3, CIT DGKQ, DIAPH1, GEFT, ITPR1, KCNA2, KTN1, MAP3K1, PKN2, PLCG1, Phospholipase D1, Protein kinase N1, RAP1GDS1, RICS, ROCK1, TRIO, and TRPC1...
45 KB (5,373 words) - 10:46, 29 June 2024
Q8N3E9 12285 PLCD4 HGNC:9062 Q9BRC7 12286 PLCE1 HGNC:17175 Q9P212 12287 PLCG1 HGNC:9065 P19174 12288 PLCG2 HGNC:9066 P16885 12289 PLCH1 HGNC:29185 Q4KWH8...
282 KB (17 words) - 07:55, 20 June 2024
MUC1, Mitogen-activated protein kinase 9, NCKIPSD, NEU3, PDGFRB, PIK3R1, PLCG1, PRKAR1A, PTK2, PTPN11, PTPN12, PTPN1, PTPN6, PTPRA, RAPGEF1, RET proto-oncogene...
82 KB (9,365 words) - 15:39, 31 March 2024
proteins that trigger downstream signaling cascades. Signaling through PLCG1, PI3K and RAAS, downstream of activated NTRK3, regulates cell survival,...
32 KB (3,936 words) - 03:00, 29 January 2024
TrkA has been shown to interact with: Abl gene, FRS2, Grb2, MATK, NGFB, PLCG1, RICS, SQSTM1, SH2B1, SH2B2, and SHC1. Small molecules such as amitriptyline...
27 KB (3,264 words) - 05:43, 13 April 2024
non-small cell lung cancer survival. FLT1 has been shown to interact with PLCG1 and vascular endothelial growth factor B (VEGF-B). VEGF receptors GRCh38:...
9 KB (1,086 words) - 00:25, 5 October 2022
translation elongation factor 1 alpha 1 has been shown to interact with: PLCG1, actin, muscarinic acetylcholine receptor, α2 subunit of GlyR, and SAMHD1...
22 KB (2,672 words) - 20:37, 3 December 2023
as a 40% reduction in brain mass. IRS2 has been shown to interact with: PLCG1, SOCS1, and PIK3R1, GRCh38: Ensembl release 89: ENSG00000185950 – Ensembl...
12 KB (1,479 words) - 01:31, 28 November 2023
stimulation Activation of the gamma isoforms of phospholipase C (PLCγ) (see PLCG1 and PLCG2 illustrates one mechanism by which FGFR1 activates cell stimulating...
44 KB (5,003 words) - 08:59, 15 July 2024
through interfering with the phosphorylation of Phospholipase C Gamma 1 (PLCG1) and Linker for Activation of T Cells (LAT). This PTP was also found to...
10 KB (1,336 words) - 05:57, 1 January 2024
phospholipase C (PLC) through different receptors like the T-cell receptor (TCR) (PLCG1[citation needed]) or B-cell receptor (BCR) (PLCG2[citation needed]). This...
23 KB (2,877 words) - 23:41, 26 April 2024
heterotrimeric G protein-coupled receptors, while the closely related C-gamma-1 (PLCG1; MIM 172420) and C-gamma-2 enzymes are controlled by receptor tyrosine kinases...
12 KB (1,405 words) - 12:49, 23 December 2023
been shown to interact with: CRK, Caveolin 1, Cbl gene, PDGFC, PDGFR-β, PLCG1, and Sodium-hydrogen antiporter 3 regulator 1. Platelet-derived growth factor...
29 KB (3,354 words) - 17:01, 9 December 2023
gene. GAB1 has been shown to interact with: CRKL, Grb2, MAP3K3, PIK3R1, PLCG1 and PTPN11. GRCh38: Ensembl release 89: ENSG00000109458 – Ensembl, May 2017...
13 KB (1,611 words) - 17:10, 22 December 2023
has been shown to interact with: GRAP2, GRAP, Grb2, ITK, MAP4K1 PIK3R1, PLCG1, SHB, VAV1, and ZAP-70. GRCh38: Ensembl release 89: ENSG00000213658 – Ensembl...
19 KB (2,288 words) - 20:03, 3 April 2024
neuronal functioning. PLCB1; PLCB2; PLCB3; PLCB4; PLCD1; PLCD3; PLCD4; PLCE1; PLCG1; PLCG2; PLCH1; PLCH2; PLCL1; PLCL2; PLCZ1 Clostridium perfringens alpha...
18 KB (2,216 words) - 15:24, 26 August 2023