Protection of telomeres protein 1 is a protein that in humans is encoded by the POT1 gene. This gene is a member of the telombin family and encodes a nuclear...
12 KB (1,200 words) - 10:49, 11 April 2024
instability, senescence, or apoptosis. Shelterin has six subunits: TRF1, TRF2, POT1, RAP1, TIN2, and TPP1. They can operate in smaller subsets to regulate the...
21 KB (2,334 words) - 07:17, 5 September 2024
found at the end of telomeres. TINF2 has been shown to interact with ACD, POT1 and TERF1. ENSG00000284915 GRCh38: Ensembl release 89: ENSG00000092330, ENSG00000284915...
9 KB (1,095 words) - 10:20, 4 January 2024
bridging factor between TRF1 and TRF2, which participate in a pathway with POT1 as a negative regulator of telomerase-dependent telomere length control,...
12 KB (1,485 words) - 07:15, 5 September 2024
POKEY (section POT1 $D201 Read)
$D200 53760 PADDL0 $0270 624 AUDC1 Audio Channel 1 Control Write $D201 53761 POT1 Potentiometer (Paddle) 1 Read $D201 53761 PADDL1 $0271 625 AUDF2 Audio Channel...
28 KB (2,886 words) - 14:09, 26 August 2024
Houghton Mifflin. 2000. ISBN 0-395-82517-2. http://www.worldwidewords.org/qa/qa-pot1.htm "Potboiler" at World Wide Words Cohen, Morton; Green, Roger, eds. (1979)...
4 KB (434 words) - 20:45, 22 April 2024
forming the telomere-binding protein complex known as shelterin: TERF1, TERF2, POT1, TIN2, RAP1 and TPP1. Both TERF1 and TERF2 bind the telomeric repeat sequences...
13 KB (1,658 words) - 08:34, 4 December 2022
shelterin complex consists of six proteins identified as TRF1, TRF2, TIN2, POT1, TPP1, and RAP1. In many species, the sequence repeats are enriched in guanine...
43 KB (4,840 words) - 05:22, 12 August 2024
P16435 12543 PORCN HGNC:17652 Q9H237 12544 POSTN HGNC:16953 Q15063 12545 POT1 HGNC:17284 Q9NUX5 12546 POTEA HGNC:33893 Q6S8J7 12547 POTEB HGNC:33734 A0A0A6YYL3...
282 KB (17 words) - 07:55, 20 June 2024
pair to form a D-loop. The joint is stabilized by the shelterin protein POT1. The T-loop, which is completed by the D-loop splice, protects the end of...
13 KB (1,432 words) - 20:29, 28 April 2024
shelterin complex enable cell cycle progress and prevent erroneous DSB repair. POT1 protein binds to ssDNA, prevents checkpoint activation through inhibiting...
22 KB (2,640 words) - 02:45, 1 December 2023
doi:10.1006/jmbi.2001.4924. PMID 11545594. Loayza D, De Lange T (June 2003). "POT1 as a terminal transducer of TRF1 telomere length control". Nature. 423 (6943):...
9 KB (1,161 words) - 18:14, 7 August 2022
Chan DW, Laegeler A, Qin J, Songyang Z (July 2004). "PTOP interacts with POT1 and regulates its localization to telomeres". Nat. Cell Biol. 6 (7): 673–80...
20 KB (2,474 words) - 11:36, 23 December 2023
ends. The six shelterin subunits are: TRF1, TRF2, TIN2, Rap1, TPP1, and POT1. Shelterin subunits are not the only proteins that associate with telomeres...
15 KB (1,654 words) - 21:36, 23 February 2024
following replication and promotes the loading of the Shelterin component POT1 onto telomere ends. This helps to stabilize the Shelterin complex so that...
35 KB (4,668 words) - 11:25, 11 February 2024
network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1". PLOS ONE. 5 (8): e12407. Bibcode:2010PLoSO...512407G. doi:10.1371/journal...
20 KB (1,947 words) - 11:18, 21 May 2024
that PROSER2 interacts with several other proteins including: STK24, ESR2, POT1, ACTB, and EPS8. These interacting proteins are involved in control of apoptosis...
20 KB (1,894 words) - 12:35, 14 February 2023
doi:10.1074/jbc.M201988200. PMID 12475993. Loayza D, De Lange T (2003). "POT1 as a terminal transducer of TRF1 telomere length control". Nature. 423 (6943):...
12 KB (1,493 words) - 17:10, 2 December 2023
Higher Education". www.theeducatoronline.com. Retrieved 7 October 2023. "POT1 loss-of-function variants predispose to familial melanoma". scholar.google...
8 KB (813 words) - 01:11, 9 October 2023