• Thumbnail for Cyclooxygenase-2
    Cyclooxygenase-2 (redirect from PTGS2)
    Prostaglandin-endoperoxide synthase 2 (HUGO PTGS2), is an enzyme that in humans is encoded by the PTGS2 gene. In humans it is one of three cyclooxygenases...
    30 KB (3,417 words) - 14:36, 15 May 2024
  • Thumbnail for Cumulus oophorus
    oocyte competence or better pregnancy outcomes, include: HAS2, GREM1 and PTGS2. In contrast, genes where increased expression is correlated with lower...
    4 KB (415 words) - 17:38, 14 February 2024
  • Thumbnail for Cyclooxygenase
    cytochrome c oxidase family. Thus, the two isozymes found in humans, PTGS1 and PTGS2, are frequently called COX-1 and COX-2 in medical literature. The names...
    16 KB (1,779 words) - 11:08, 3 July 2024
  • the COX-2 enzyme. MAPK pathways may also play a role in the regulation of PTGS2. Growth factor MAPK/ERK pathway Lectins Bohmer et al. "Cytoskeletal Integrity...
    13 KB (1,750 words) - 10:12, 12 August 2024
  • PTGS2 antisense NFKB1 complex-mediated expression regulator RNA is a protein that in humans is encoded by the PACERR gene. This gene represents transcription...
    839 bytes (103 words) - 19:44, 15 October 2023
  • Thumbnail for Mechanism of action of aspirin
    at least two different cyclooxygenase isozymes: COX-1 (PTGS1) and COX-2 (PTGS2). Aspirin is non-selective and irreversibly inhibits both forms (but is...
    15 KB (1,734 words) - 04:18, 25 March 2024
  • Thumbnail for Chromosome 1
    Opticin OTUD7B: OTU domain-containing protein 7B PACERR encoding protein PTGS2 antisense NFKB1 complex-mediated expression regulator RNA PBX1 (1q23) PEA15...
    46 KB (3,290 words) - 20:16, 17 August 2024
  • Thumbnail for Arachidonic acid
    cyclooxygenase-1 and -2 (i.e. prostaglandin G/H synthase 1 and 2 {PTGS1 and PTGS2}) convert arachidonic acid to prostaglandin G2 and prostaglandin H2, which...
    21 KB (1,900 words) - 21:15, 28 July 2024
  • Cyclooxygenase-2 inhibitors (COX-2 inhibitors), also known as coxibs, are a type of nonsteroidal anti-inflammatory drug (NSAID) that directly target cyclooxygenase-2...
    42 KB (4,944 words) - 11:56, 4 April 2024
  • Thumbnail for Cyclooxygenase-1
    Takahashi E, Tanabe T (May 1994). "Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2". European Journal of Biochemistry...
    18 KB (2,122 words) - 12:15, 2 June 2024
  • Thumbnail for Interleukin 1 beta
    proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute...
    26 KB (3,273 words) - 13:58, 26 August 2024
  • Thumbnail for Aspirin
    proinflammatory. Aspirin-modified COX-2 (aka prostaglandin-endoperoxide synthase 2 or PTGS2) produces lipoxins, most of which are anti-inflammatory.[verification needed]...
    152 KB (16,401 words) - 19:52, 4 September 2024
  • Q8N8N7 13105 PTGR3 HGNC:28697 Q8N4Q0 13106 PTGS1 HGNC:9604 P23219 13107 PTGS2 HGNC:9605 P35354 13108 PTH HGNC:9606 P01270 13109 PTH1R HGNC:9608 Q03431...
    282 KB (17 words) - 07:55, 20 June 2024
  • Thumbnail for Eicosanoid
    and COX2 (also termed prostaglandin-endoperoxide synthase-1 (PTGS1) and PTGS2, respectively) metabolize arachidonic acid by adding molecular O2 between...
    84 KB (9,648 words) - 10:14, 12 September 2024
  • Thumbnail for Prostacyclin synthase
    PMID 19265782. Xie X, Ma YT, Fu ZY, et al. (2009). "Association of polymorphisms of PTGS2 and CYP8A1 with myocardial infarction". Clin. Chem. Lab. Med. 47 (3): 347–52...
    10 KB (1,212 words) - 09:20, 13 April 2024
  • Thumbnail for Interleukin-17A
    This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). IL-17A,...
    53 KB (6,247 words) - 19:58, 2 April 2024
  • Thumbnail for Animal heme-dependent peroxidases
    human proteins containing this domain: DUOX1; DUOX2; EPX; LPO; MPO; PTGS1; PTGS2; PXDNL; TPO PDB: 1dnu​; Blair-Johnson M, Fiedler T, Fenna R (November 2001)...
    8 KB (877 words) - 05:11, 3 December 2023
  • Thumbnail for Caveolin 1
    epidermal growth factor receptor, endothelin receptor type B, PDGFRB, PDGFRA, PTGS2, TRAF2, estrogen receptor alpha, caveolin 2, PLD2, Bruton's tyrosine kinase...
    14 KB (1,555 words) - 20:31, 22 August 2024
  • Thumbnail for EGF-like domain
    NRXN3; NTNG2; ODZ1; ODZ2; OIT3; PLAT; PP187; PROC; PROS1; PROZ; PTGS1; PTGS2; RAMP; SCUBE1; SCUBE2; SCUBE3; SEL-OB; SELE; SELL; SELP; SLIT1; SLIT2; SLIT3;...
    25 KB (3,071 words) - 16:22, 5 September 2024