chemistry, peptide synthesis is the production of peptides, compounds where multiple amino acids are linked via amide bonds, also known as peptide bonds....

constituents Peptide synthesis, the biochemical synthesis of peptides using amino acids Protein biosynthesis, the multi-step biochemical synthesis of proteins...

Nonribosomal peptides (NRP) are a class of peptide secondary metabolites, usually produced by microorganisms like bacteria and fungi. Nonribosomal peptides are...

a base-labile amine protecting group used in organic synthesis, particularly in peptide synthesis. It is popular for its stability toward acids and hydrolysis...

to synthesise peptide chains, and which was the basis for his 1984 Nobel Prize in Chemistry. In the basic method of solid-phase synthesis, building blocks...

chain being synthesised. As the amino acids get linked into the growing peptide chain, the chain begins folding into the correct conformation. Translation...

Bailey peptide synthesis is a name reaction in organic chemistry developed 1949 by J. L. Bailey. It is a method for the synthesis of a peptide from α-amino...

To make protein-sized polypeptide chains with the small peptide fragments made by synthesis, chemical biologists can use the process of native chemical...

Peptides are short chains of amino acids linked by peptide bonds. A polypeptide is a longer, continuous, unbranched peptide chain. Polypeptides that have...

Glucagon-like peptide-1 (GLP-1) is a 30- or 31-amino-acid-long peptide hormone deriving from the tissue-specific posttranslational processing of the proglucagon...

Nobel Prize in Chemistry in 1984 for the invention of solid phase peptide synthesis. He was born in Fort Worth, Texas, on 15 July 1921, the only son of...

Rockefeller University. Her research considers peptide synthesis. She discovered the glucagon-like peptide-1 and uncovered its role in glucose metabolism...

Bruce Merrifield, started investigating the solid-phase synthesis of peptides. Synthesis of peptides in a combinatorial fashion quickly leads to large numbers...

produce peptides at sufficient concentrations. Thus, mineral surface catalysis, while important, is not sufficient alone for peptide synthesis. Many prebiotically...

Beta-peptides (β-peptides) are peptides derived from β-amino acids, in which the amino group is attached to the β-carbon (i.e. the carbon two atoms away...

arise from post-translational modification or during nonribosomal peptide synthesis. The carbon atom next to the carboxyl group is called the α–carbon...

single-enantiomer chiral molecules and to improve the efficiency of peptide synthesis. Automated peptide synthesis involves the condensation of the amino group of protected...

Proteins are made of amino acids arranged in a linear chain joined by peptide bonds. Many proteins are enzymes that catalyze the chemical reactions in...

strategy a peptide chain and glycan residue are first synthesis separately. Then the glycan is glycosylated onto a specific residue of the peptide chain....

additional oxygens attached. The chemical is a useful reagent for peptide synthesis reactions, where it activates the carboxylic acid partner for subsequent...

Protein biosynthesis (or protein synthesis) is a core biological process, occurring inside cells, balancing the loss of cellular proteins (via degradation...

Schematic diagram of a solid-state peptide synthesis with orthogonal protecting groups X and Y Fmoc solid state peptide synthesis with orthogonal protecting groups...

Custom peptide synthesis is the commercial production of peptides for use in biochemistry, biology, biotechnology, pharmacology and molecular medicine...

peptide synthesis methods. These rely on organic synthesis techniques such as chemical ligation to produce peptides in high yield. Chemical synthesis...

scavenger in peptide synthesis. It can also act as a mild reducing agent. In peptide synthesis, TIPS is used as a scavenger for peptide groups being removed...

odor. Its primary use is to couple amino acids during artificial peptide synthesis. The low melting point of this material allows it to be melted for...

protein is denatured, secondary and tertiary structures are altered but the peptide bonds of the primary structure between the amino acids are left intact...

for reaction with amines in the context of amide bond formation and peptide synthesis. TCFH is commercially available. It may be prepared from tetramethylurea...

phosphomonoesters and phosphodiesters. Common uses for this carbodiimide include peptide synthesis, protein crosslinking to nucleic acids, but also in the preparation...

Electrosynthesis Methods in Organic Synthesis Organic synthesis Peptide synthesis Total synthesis Automated synthesis Vogel, A.I.; Tatchell, A.R.; Furnis...