Pitolisant, sold under the brand name Wakix among others, is a medication used for the treatment of excessive daytime sleepiness in adults with narcolepsy...
22 KB (1,703 words) - 10:56, 6 November 2024
Stimulant (section Pitolisant)
the brain. Pitolisant is an histamine 3 (H3)-receptor inverse agonist. As histamine 3 (H3) receptors mainly act as autoreceptors, pitolisant decreases...
128 KB (13,210 words) - 11:00, 6 November 2024
H3 receptor antagonist (section Pitolisant)
clobenpropit, ABT-239, ciproxifan, conessine, A-349,821, betahistine, and pitolisant. The histamine H3 receptor (H3R) was discovered in 1983 and was one of...
19 KB (2,154 words) - 12:44, 26 September 2024
histamine release in hypothalamus. An inverse agonist of the histamine H3 is Pitolisant. Results after testing on animals have indicated increased wakefulness...
22 KB (2,504 words) - 17:02, 19 October 2024
These medications include alerting agents (e.g., modafinil, armodafinil, pitolisant, solriamfetol), oxybate medications (e.g., twice nightly sodium oxybate...
71 KB (8,222 words) - 20:42, 31 October 2024
conditions such as long QT syndrome, by certain medications such as sotalol or pitolisant, by disturbances in the concentrations of certain salts within the blood...
29 KB (3,277 words) - 05:30, 8 September 2024
istradefylline Histamine H3 receptor antagonists and inverse agonists like pitolisant and samelisant Orexin receptor agonists like danavorexton and suntinorexton...
15 KB (1,329 words) - 14:59, 6 November 2024
may cure the person from the EDS. Drugs like modafinil, armodafinil, pitolisant (Wakix), sodium oxybate (Xyrem) oral solution, have been approved as treatment...
19 KB (1,810 words) - 11:01, 6 November 2024
(nCPAP) Therapy (0249-015). http://ClinicalTrials.gov/show/NCT00620659 Pitolisant to Assess Weekly Frequency of Cataplexy Attacks and EDS in Narcoleptic...
31 KB (3,617 words) - 20:04, 22 October 2024
2011). "The histamine H3 receptor: from discovery to clinical trials with pitolisant". British Journal of Pharmacology. 163 (4): 713–21. doi:10.1111/j.1476-5381...
3 KB (128 words) - 16:47, 3 October 2023
Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681...
88 KB (7,952 words) - 17:10, 29 October 2024
agonists: Loratadine Histamine 3 (H3) receptor antagonists/inverse agonists: Pitolisant SERM (selective estrogen receptor modulators) Raloxifene Vasodilators...
17 KB (1,471 words) - 09:57, 23 October 2024
Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681...
36 KB (3,292 words) - 00:41, 26 October 2024
or sodium oxybate (as first line); methylphenidate and pitolisant (as second line [pitolisant is currently only available in Europe]); and amphetamines...
45 KB (14,062 words) - 20:53, 26 October 2024
Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681...
62 KB (5,826 words) - 16:29, 30 September 2024
Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681...
15 KB (1,148 words) - 05:31, 15 October 2024
Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681...
17 KB (1,490 words) - 12:21, 7 November 2024
Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681...
55 KB (5,138 words) - 05:15, 27 October 2024
Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681...
11 KB (1,209 words) - 13:04, 16 July 2024
Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681...
32 KB (2,680 words) - 04:25, 26 October 2024
and Emmanuelle. He is a member of the Academy of Sciences. He developed pitolisant, the first clinically approved antagonist for H3 receptors. Jean-Charles...
12 KB (1,502 words) - 02:32, 4 October 2024
Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681...
21 KB (1,748 words) - 12:42, 5 August 2024
Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681...
92 KB (8,729 words) - 03:44, 26 October 2024
Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681...
21 KB (1,712 words) - 11:08, 17 October 2024
or sodium oxybate (as first line); methylphenidate and pitolisant (as second line [pitolisant is currently only available in Europe]); and amphetamines...
274 KB (28,856 words) - 03:42, 2 November 2024
or sodium oxybate (as first line); methylphenidate and pitolisant (as second line [pitolisant is currently only available in Europe]); and amphetamines...
63 KB (21,867 words) - 04:56, 7 November 2024
Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681...
27 KB (2,349 words) - 02:38, 2 November 2024
(6): 642–650. doi:10.1002/cpt.319. PMC 4862932. PMID 26660002. "Wakix pitolisant tablets Prescribing Information" (PDF). Wakix HCP. Archived (PDF) from...
45 KB (3,776 words) - 06:27, 23 September 2024
Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681...
23 KB (2,159 words) - 08:29, 16 September 2024
samelisant is in phase 2 clinical trials for the treatment of narcolepsy. Pitolisant "Samelisant - Suven Life Sciences". AdisInsight. 12 June 2024. Retrieved...
4 KB (272 words) - 14:44, 6 November 2024