intestinal peptide receptor and to the pituitary adenylate cyclase-activating polypeptide receptor. This gene encodes adenylate cyclase-activating polypeptide...

B VIP (Vasoactive Intestinal Peptide; PHM27) PACAP Pituitary Adenylate Cyclase Activating Peptide Peptide PHI 27 (Peptide Histidine Isoleucine 27) GHRH...

encoded by the ADCYAP1R1 gene. This receptor binds pituitary adenylate cyclase activating peptide. PAC1 is a membrane-associated protein and shares significant...

neurons of the trigeminal ganglion that are involved in pituitary adenylate cyclase-activating peptide neuropeptide signaling project the gland. The canonical...

(February 1995). "Helospectin and pituitary adenylate cyclase activating polypeptide in the human vagina". Regulatory Peptides. 55 (3): 277–86. doi:10...

from the hypothalamus include: Forskolin Interleukin-6 Pituitary adenylate cyclase-activating peptide (PACAP) Stress or trauma Circadian rhythms Forskolin...

factor (FGF), platelet-derived growth factor (PDGF), pituitary adenylate cyclase-activating peptide (PACAP), interleukin-1 (IL-1), interleukin-2 (IL-2)...

vasoactive intestinal peptide (VIP) termed VPAC1 and VPAC2. These receptors bind both VIP and pituitary adenylate cyclase-activating polypeptide (PACAP)...

bipolar, and found to be under-expressed in the cortex. Pituitary adenylate cyclase-activating peptide has been associated with bipolar in gene linkage studies...

(November 1998). "An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation". Nature Structural Biology...

These receptors are linked to the G protein Gs, which activates adenylate cyclase and activation results in the generation of intracellular cyclic adenosine...

heparan sulfate chains. A mitogenic growth factor activity was found in pituitary extracts by Armelin in 1973 and further work by Gospodarowicz as reported...

peptides. Monoamines are synthesized by altering a single amino acid. For example, the precursor of serotonin is the amino acid tryptophan. Peptide neurotransmitters...

neurotrophins which are released as biologically active uncleaved pro-peptides. Unlike mature neurotrophins which bind to the p75NTR with a low affinity...

2 nM in one study. The activation of the GR by dexamethasone results in dose-dependent suppression of the hypothalamic–pituitary–adrenal axis (HPA axis)...

intramolecular disulfide bonds. EGF was originally described as a secreted peptide found in the submaxillary glands of mice and in human urine. EGF has since...

are positive for the T790M mutation in the gene coding for EGFR or for activating EGFR mutations. The T790M mutation may be de novo or acquired following...

increased uptake from bones activate vitamin D ) 52 Pituitary adenylate cyclase-activating peptide PACAP Peptide multiple ADCYAP1R1, VIPR1, VIPR2 Stimulates...

identified that a modified version of imatinib can bind to gamma-secretase activating protein (GSAP). GSAP selectively increases the production and accumulation...

is an inducer of EMT, particularly in mammary development. Insulin is a peptide hormone involved in glucose homeostasis within certain organisms. Specifically...

to how this particular variant maintains interactions with the GTPase activating protein (GAP) NFI. Observations on EGFR inhibition were published in 1988...

include: PDGFA; PDGFB; PDGFC; PDGFD PGF VEGF; VEGFB; VEGFC; VEGFD Platelet-activating factor Platelet-derived growth factor receptor atheroma platelet involvement...

supportive as no specific antidote for amitriptyline overdose is available. Activated charcoal may reduce absorption if given within 1–2 hours of ingestion...

hamsters. In 1989 Ferrara and Henzel described an identical factor in bovine pituitary follicular cells which they purified, cloned and named VEGF. A similar...

cell–extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal transduction pathways that mediate cellular signals such as regulation...

Migration-stimulating factor (MSF; PRG4) Oncomodulin Pituitary adenylate cyclase-activating peptide (PACAP) Pleiotrophin Renalase Thrombopoietin (see here...

proteins then link (dimerize), activating the receptor. HER2 sends a signal from its intracellular domain, activating several different biochemical pathways...

non-small cell lung cancer with Epidermal Growth Factor Receptor (EGFR) activating mutations. In December 2010, the US Food and Drug Administration (FDA)...

associated with the disorder. The hippocampus instructs the hypothalamic-pituitary-adrenal axis to produce fewer glucocorticoids when glucocorticoid levels...

intended for the treatment of non-small cell lung cancer (NSCLC) with activating epidermal growth factor receptor (EGFR) exon 20 insertion mutations. The...