Plakophilin-2 is a protein that in humans is encoded by the PKP2 gene. Plakophilin 2 is expressed in skin and cardiac muscle, where it functions to link...

Plakophilin-1 is a protein that in humans is encoded by the PKP1 gene. This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families...

McDermott DA, et al. (November 2004). "Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy". Nature...

van Roy F (April 2003). "Defining desmosomal plakophilin-3 interactions". The Journal of Cell Biology. 161 (2): 403–16. doi:10.1083/jcb.200303036. PMC 2172904...

2007). "A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac...

p120-catenin, plakoglobin (γ-catenin), and plakophilins 1-3. In desmosomes, plakoglobin and plakophilin help to anchor desmoplakin and keratin filaments...

therapy for arrhythmogenic cardiomyopathy caused by mutations to the plakophilin-2 gene. It is delivered via adeno-associated virus and was developed by...

Plakophilin are proteins of the cytoskeleton. They are involved in regulating the adhesive activity of cadherin. The three types of plakophilin proteins...

desmosomal cadherins bind to plakoglobin and plakophilins, which bind desmoplakin. In cardiac muscle, desmoglein-2 localizes to the intercalated disc, responsible...

junctional plaque protein plakophilin 3 in cytoplasmic particles containing RNA-binding proteins and the recruitment of plakophilins 1 and 3 to stress granules"...

Plakophilin-4 is a protein that in humans is encoded by the PKP4 gene. Armadillo-like proteins are characterized by a series of armadillo repeats, first...

Plakophilin-3 is a protein that in humans is encoded by the PKP3 gene. This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families...

localization to the desmosome and interaction with the N-terminal region of plakophilin 1 and plakoglobin as well as desmocollin and desmoglein. This is further...

proteins, such as calmodulin, calmodulin kinase II δc, ankyrin-G and plakophilin-2, are known to interact and modulate function of NaV1.5. Some of these...

altered expression of proteins, including Neural Cadherin (CDH2) and Plakophilin-2 (PKP2), which naturally promote gap junction expression. Decreased CDH2...

Striate palmoplantar keratoderma ARVD Plakophilin 1 Ectodermal dysplasia–skin fragility syndrome Plakophilin 2 ARVD Corneodesmosin Hypertrichosis simplex...

"Arrhythmogenic right ventricular cardiomyopathy caused by deletions in plakophilin-2 and plakoglobin (Naxos disease) in families from Greece and Cyprus:...

the first mutation responsible for sinus node disease and identified plakophilin-2 as the most common mutation underlying arrhythmogenic right ventricular...

KJ (March 2002). "Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling"...

"Super-resolution fluorescence microscopy of the cardiac connexome reveals plakophilin-2 inside the connexin43 plaque", Cardiovasc Res. 100 (2013) 231-240. doi:10...

2017). "Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction". Nature Communications. 8: 13876. Bibcode:2017NatCo...

et al. (2002). "Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling"...

Skin fragility syndrome (also known as "plakophilin 1 deficiency") is a cutaneous condition characterized by trauma-induced blisters and erosions. It...

Inagaki M (February 2002). "Densin-180 interacts with delta-catenin/neural plakophilin-related armadillo repeat protein at synapses". The Journal of Biological...

human body. Fibrillin-2 was isolated in 1994 by Zhang and is thought to play a role in early elastogenesis. Mutations in the fibrillin-2 gene have been linked...

the MAP by the MARK causes the MAP to detach from any bound microtubules.[2] This detachment is usually associated with a destabilization of the microtubule...

Alpha-actinin-2 is a protein which in humans is encoded by the ACTN2 gene. This gene encodes an alpha-actinin isoform that is expressed in both skeletal...

Keratin 2A also known as keratin 2E or keratin 2 is a protein that in humans is encoded by the KRT2A gene. Keratin 2A is a type II cytokeratin. It is...

genes, 28 are in the Keratin type 1 family, and 26 are in the Keratin type 2 family. Fibrous keratin molecules supercoil to form a very stable, left-handed...

Myosin-2 (myosin heavy chain 2) is a protein that in humans is encoded by the MYH2 gene. GRCh38: Ensembl release 89: ENSG00000125414 – Ensembl, May 2017...