Platelet-activating factor, also known as PAF, PAF-acether or AGEPC (acetyl-glyceryl-ether-phosphorylcholine), is a potent phospholipid activator and...
16 KB (1,930 words) - 01:51, 11 December 2023
The platelet-activating factor receptor (PAF-R) is a G-protein coupled receptor which binds platelet-activating factor. It is encoded in the human by the...
9 KB (1,097 words) - 22:30, 27 March 2024
Coagulation (redirect from Platelet activation)
vessel wall). Activation of platelets and platelet plug formation: Platelet activation: Platelet activators, such as platelet activating factor and thromboxane...
64 KB (6,553 words) - 02:03, 21 November 2024
Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
24 KB (2,882 words) - 16:31, 25 October 2024
Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4) . This...
14 KB (1,641 words) - 23:08, 5 September 2024
In enzymology, a platelet-activating factor acetyltransferase (EC 2.3.1.149) is an enzyme that catalyzes the chemical reaction 1-alkyl-2-acetyl-sn-gly...
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Lipoprotein-associated phospholipase A2 (Lp-PLA2) also known as platelet-activating factor acetylhydrolase (PAF-AH) is a phospholipase A2 enzyme that in...
12 KB (1,378 words) - 21:36, 20 September 2024
1-alkyl-2-acetylglycerophosphocholine esterase (redirect from Platelet-activating factor acetylhydrolase)
as platelet-activating factor. There are multiple enzymes with this function: Lipoprotein-associated phospholipase A2 Platelet-activating factor acetylhydrolase...
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Rupatadine is a second generation antihistamine and platelet-activating factor antagonist used to treat allergies. It was discovered and developed by Uriach [es]...
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Platelet-activating factor acetylhydrolase IB subunit alpha or Lisencephaly protein-1 (LIS-1) is an enzyme that in humans is encoded by the PAFAH1B1 gene...
13 KB (1,513 words) - 08:56, 16 June 2024
with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot. Platelets have no cell nucleus;...
71 KB (8,533 words) - 22:28, 12 November 2024
Jacques Benveniste (section Platelet-activating factor)
In 1979, he published a well-known paper on the structure of platelet-activating factor and its relationship with histamine. He was head of allergy and...
29 KB (3,101 words) - 20:17, 25 August 2024
Platelet-activating factor acetylhydrolase IB subunit beta is an enzyme that in humans is encoded by the PAFAH1B2 gene. PAFAH1B2 has been shown to interact...
6 KB (727 words) - 06:40, 7 January 2024
Platelet-activating factor acetylhydrolase IB subunit gamma is an enzyme that in humans is encoded by the PAFAH1B3 gene. PAFAH1B3 has been shown to interact...
6 KB (730 words) - 07:59, 18 August 2023
Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family...
13 KB (1,563 words) - 09:00, 13 March 2024
primarily by activation of ceramidase by growth-inducing proteins such as platelet-derived growth factor and insulin-like growth factor, is consistent...
55 KB (5,633 words) - 08:40, 12 July 2024
cytokines, chemokines, growth factors, lipid mediators (e.g. leukotrienes, prostaglandins, platelet activating factor), and toxic proteins (e.g. metalloproteinases...
50 KB (5,523 words) - 06:20, 11 November 2024
Von Willebrand factor (VWF) (German: [fɔn ˈvɪləbʁant]) is a blood glycoprotein that promotes hemostasis, specifically, platelet adhesion. It is deficient...
17 KB (2,121 words) - 09:32, 20 August 2024
a potent and selective inhibitor of the phospholipid mediator platelet-activating factor (PAF). It was developed by structural modification of the...
3 KB (258 words) - 19:51, 7 September 2024
tissue trauma. Mast cell granules contain histamine, heparin, platelet-activating factor, and other substances. Disseminated mastocytosis is rarely seen...
19 KB (2,282 words) - 19:32, 29 August 2024
extension of PortableApps files Paroxysmal atrial fibrillation Platelet-activating factor Population attributable fraction (epidemiology) Pure autonomic...
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Fc receptor (section Activation)
proteases. Activated mast cells also synthesize and secrete lipid-derived mediators (such as prostaglandins, leukotrienes, and platelet-activating factor) and...
42 KB (4,735 words) - 17:25, 20 November 2024
hours. Factor V is able to bind to activated platelets and is activated by thrombin. On activation, factor V is spliced in two chains (heavy and light...
14 KB (1,814 words) - 07:38, 3 June 2024
substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both...
5 KB (583 words) - 19:49, 8 April 2022
class of molecules has been studied for its potential to act as a platelet-activating factor receptor antagonist. Ginkgolide B has been investigated for its...
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causing degranulation. Granules in these cells contain histamine, platelet-activating factor, and other compounds causing clinical manifestation of anaphylaxis-...
44 KB (4,096 words) - 22:53, 25 October 2024
(dialkenylphospholipids) also exist. The prototypical plasmalogen is platelet-activating factor. The formation of the ether bond in mammals requires two enzymes...
13 KB (1,392 words) - 19:36, 23 February 2024
and hydrogels, and for positron emission tomography. Hexadecyl platelet-activating factor has profound effects on the lung, and hexadecyl glyceryl ether...
8 KB (562 words) - 17:41, 5 March 2024
v t e PAF receptor modulators PAFRTooltip Platelet-activating factor receptor Others See also Receptor/signaling modulators...
36 KB (3,347 words) - 11:03, 24 September 2024
neurotrophic factor (BDNF) Nerve growth factor (NGF) Neurotrophin-3 (NT-3) Neurotrophin-4 (NT-4) Placental growth factor (PGF) Platelet-derived growth factor (PDGF)...
10 KB (1,131 words) - 19:14, 31 March 2024