• The Polycystin Cation Channel (PCC) Family (TC# 1.A.5) consists of several transporters ranging in size from 500 to over 4000 amino acyl residues (aas)...
    11 KB (1,385 words) - 04:58, 3 September 2023
  • are molecular sensing, non-selective cation channels that have six transmembrane segments, however, each sub-family is unique and shares little structural...
    49 KB (5,517 words) - 15:04, 1 October 2024
  • Thumbnail for Polycystin 2
    Information, U.S. National Library of Medicine. "PKD2 polycystin 2, transient receptor potential cation channel [Homo sapiens (human)] - Gene - NCBI". www.ncbi...
    11 KB (1,206 words) - 19:21, 1 August 2023
  • in the interaction with the polycystin-1 group. TRPP1 and TRPP3 form constitutively active cation-selective ion channels that are permeable to calcium...
    4 KB (403 words) - 08:03, 16 April 2022
  • Thumbnail for Ion channel
    the sodium channels and are equally large. Cation channels of sperm: This small family of channels, normally referred to as Catsper channels, is related...
    46 KB (5,308 words) - 19:08, 1 November 2024
  • Thumbnail for Polycystin 1
    coiled-coil domain through which PC1 interacts with polycystin 2 (PC2), a membrane-bound Ca2+-permeable ion channel. PC1 has been proposed to act as a G protein–coupled...
    7 KB (839 words) - 22:04, 22 December 2023
  • Thumbnail for Voltage-gated ion channel
    potential Ca2+ channels, polycystin cation channels, glutamate-gated ion channels, calcium-dependent chloride channels, monovalent cation:proton antiporters...
    21 KB (2,298 words) - 12:09, 9 August 2024
  • potential cation channel, mucolipin subfamily) comprises a group of three evolutionarily related proteins that belongs to the large family of transient...
    3 KB (350 words) - 08:03, 16 April 2022
  • channel family 1.A.5 Polycystin cation channel family 1.A.6 Epithelial Na+ channel family 1.A.7 ATP-gated P2X receptor cation channel family 1.A.8 Major intrinsic...
    38 KB (5,159 words) - 15:41, 17 April 2024
  • Thumbnail for PKD2L1
    Chen XZ, Vassilev PM, Basora N, et al. (1999). "Polycystin-L is a calcium-regulated cation channel permeable to calcium ions". Nature. 401 (6751): 383–6...
    5 KB (712 words) - 18:25, 29 January 2023
  • thirst). The channels vary in selectivity for the permeating ions from nonselective between anions and cations in bacteria, to cation selective allowing...
    66 KB (7,825 words) - 22:28, 16 July 2024
  • potential Ca2+ channel (TRP-CC) family (TC# 1.A.4) is a member of the voltage-gated ion channel (VIC) superfamily and consists of cation channels conserved...
    13 KB (1,621 words) - 02:21, 29 November 2023
  • Thumbnail for Polycystic kidney disease
    formation are tied to abnormal cilia-mediated signaling. The polycystin-1 and polycystin-2 proteins appear to be involved in both autosomal dominant and...
    27 KB (2,798 words) - 02:17, 28 October 2024
  • Thumbnail for TRPP3
    TRPP3 (category Ion channels)
    Zhao W, Chen XZ (2002). "The calcium-binding EF-hand in polycystin-L is not a domain for channel activation and ensuing inactivation". FEBS Lett. 516 (1–3):...
    2 KB (299 words) - 00:23, 17 July 2024
  • Thumbnail for Autosomal dominant polycystic kidney disease
    its large extracellular domains, activating the calcium channels associated with polycystin-2, the product of gene PKD2, as a result of the genetic setting...
    57 KB (6,324 words) - 00:04, 30 April 2024
  • Thumbnail for ISLR
    (leucine-rich repeat), LRR_RI (ribonuclease inhibitor), PCC (polycystin cation channel protein) Super family, and Ig (immunoglobulin). The predicted isoelectric...
    46 KB (3,998 words) - 06:32, 20 September 2024