• Thumbnail for Prostaglandin E1
    Prostaglandin E1 (PGE1) is a naturally occurring prostaglandin and is also used as a medication (alprostadil). In infants with congenital heart defects...
    13 KB (1,105 words) - 07:16, 28 May 2024
  • Thumbnail for Prostaglandin
    For example, prostaglandin E1 has the abbreviation PGE1 and prostaglandin I2 has the abbreviation PGI2. Systematic studies of prostaglandins began in 1930...
    24 KB (2,463 words) - 17:42, 11 July 2024
  • Thumbnail for Prostaglandin E2
    Health Organization's List of Essential Medicines. Prostaglandin E2 works as well as prostaglandin E1 in babies. Dinoprostone has important effects in labor...
    34 KB (3,565 words) - 20:10, 14 May 2024
  • Thumbnail for Prostacyclin
    Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation...
    20 KB (1,639 words) - 08:58, 22 December 2023
  • Thumbnail for Cyclooxygenase
    Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes, EC 1.14.99.1)...
    16 KB (1,779 words) - 11:08, 3 July 2024
  • Thumbnail for Aspirin
    of Surgeons in London, showed aspirin suppressed the production of prostaglandins and thromboxanes. For this discovery he was awarded the 1982 Nobel Prize...
    152 KB (16,417 words) - 06:03, 6 August 2024
  • Thumbnail for Paracetamol
    especially similar to selective COX-2 inhibitors. Paracetamol inhibits prostaglandin synthesis by reducing the active form of COX-1 and COX-2 enzymes. This...
    123 KB (12,177 words) - 11:09, 10 August 2024
  • enzymes are involved in the synthesis of key biological mediators, namely prostaglandins, which are involved in inflammation, and thromboxanes, which are involved...
    110 KB (11,559 words) - 18:11, 8 August 2024
  • Thumbnail for Misoprostol
    Misoprostol (category Prostaglandins)
    cases, uterine rupture may occur. It is a prostaglandin analogue—specifically, a synthetic prostaglandin E1 (PGE1). Misoprostol was developed in 1973...
    51 KB (4,767 words) - 15:29, 17 July 2024
  • Thumbnail for Cyclooxygenase-1
    Cyclooxygenase 1 (COX-1), also known as prostaglandin-endoperoxide synthase 1 (HUGO PTGS1), is an enzyme that in humans is encoded by the PTGS1 gene....
    18 KB (2,122 words) - 12:15, 2 June 2024
  • Thumbnail for Carprofen
    administered intravenously to horses. A single dose has been shown to reduce prostaglandin E2 production and inflammatory exudate for up to 15 hours, although...
    18 KB (1,685 words) - 21:57, 1 July 2024
  • Thumbnail for Prostaglandin F2alpha
    Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost is a naturally occurring prostaglandin used in medicine to induce...
    12 KB (1,134 words) - 18:55, 24 April 2024
  • Thumbnail for Ketoprofen
    antipyretic effects. It acts by inhibiting the body's production of prostaglandin. It was patented in 1967 and approved for medical use in 1980. Ketoprofen...
    18 KB (1,848 words) - 13:53, 1 July 2024
  • growths in the intestinal tract. Overexpression of COX-2 produces excess prostaglandins, which have been shown to increase the possibility of colorectal cancer...
    42 KB (4,944 words) - 11:56, 4 April 2024
  • Thumbnail for Indometacin
    swelling from inflammation. It works by inhibiting the production of prostaglandins, endogenous signaling molecules known to cause these symptoms. It does...
    23 KB (2,294 words) - 14:58, 28 July 2024
  • Thumbnail for Ketorolac
    non-selectively to block the prostaglandin synthesis by inhibition of prostaglandin G/H synthesis 1 and 2. Prostaglandin functions in the body as a messenger...
    25 KB (2,264 words) - 23:10, 26 May 2024
  • Thumbnail for Ibuprofen
    period. Like other NSAIDs, it works by inhibiting the production of prostaglandins by decreasing the activity of the enzyme cyclooxygenase (COX). Ibuprofen...
    60 KB (5,863 words) - 17:15, 10 August 2024
  • Thumbnail for Arachidonic acid
    in animal fats. It is a precursor in the formation of leukotrienes, prostaglandins, and thromboxanes. Together with omega-3 fatty acids and other omega-6...
    21 KB (1,900 words) - 21:15, 28 July 2024
  • Thumbnail for Lubiprostone
    citation needed] Lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the...
    15 KB (1,360 words) - 06:26, 7 April 2024
  • Thumbnail for Dexketoprofen
    involved in the production of chemicals in the body called prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would...
    5 KB (408 words) - 12:35, 14 July 2024
  • Thumbnail for Clitoral erection
    ; Wang, T. N.; Lue, F. (April 1995). "Duplex ultrasonography after prostaglandin E1 injection of the clitoris in a case of hyperreactio luteinalis". The...
    14 KB (1,399 words) - 13:33, 18 July 2024
  • Thumbnail for Prostaglandin E
    Prostaglandin E is a family of naturally occurring prostaglandins that are used as medications. Types include: Prostaglandin E1 also known as alprostadil...
    5 KB (148 words) - 21:50, 4 March 2021
  • Prostaglandin analogues are a class of drugs that bind to a prostaglandin receptor. Wider use of prostaglandin analogues is limited by unwanted side effects...
    3 KB (342 words) - 21:37, 11 July 2024
  • Thumbnail for Bimatoprost
    Bimatoprost (category Prostaglandins)
    during pregnancy or breastfeeding is generally not recommended. It is a prostaglandin analog and works by increasing the outflow of aqueous fluid from the...
    15 KB (1,239 words) - 03:34, 5 August 2024
  • Thumbnail for Naproxen
    action by reducing the production of inflammatory mediators called prostaglandins. It is metabolized by the liver to inactive metabolites. Naproxen was...
    34 KB (3,174 words) - 04:50, 18 July 2024
  • Thumbnail for Nimesulide
    characterized by a fast onset of action. It works by blocking the production of prostaglandins (a chemical associated with pain), thereby relieving pain and inflammation...
    18 KB (1,753 words) - 20:40, 17 July 2024
  • Thumbnail for Aceclofenac
    action of cyclooxygenase (COX) that is involved in the production of prostaglandins (PG) which is accountable for pain, swelling, inflammation and fever...
    7 KB (445 words) - 15:09, 7 November 2023
  • Thumbnail for Selenium
    Misoprostol Prostaglandin E1 (alprostadil) Prostaglandin E2 (dinoprostone) Treprostinil Antagonists: AH-6809 PF-04418948 TG 4-155 EP3Tooltip Prostaglandin EP3...
    95 KB (11,044 words) - 15:17, 10 August 2024
  • 10–20 μg of prostaglandin E1, with evaluations of the arterial flow every five minutes for 25–30 min (see image). The use of prostaglandin E1 is contraindicated...
    68 KB (7,128 words) - 18:29, 30 July 2024
  • Thumbnail for Diclofenac
    breastfeeding. Diclofenac is believed to work by decreasing the production of prostaglandins, like other drugs in this class. In 2021, diclofenac was the 61st most...
    58 KB (5,599 words) - 23:32, 10 June 2024