Prostaglandin E1 (PGE1) is a naturally occurring prostaglandin and is also used as a medication (alprostadil). In infants with congenital heart defects...
13 KB (1,105 words) - 07:16, 28 May 2024
For example, prostaglandin E1 has the abbreviation PGE1 and prostaglandin I2 has the abbreviation PGI2. Systematic studies of prostaglandins began in 1930...
24 KB (2,463 words) - 17:42, 11 July 2024
Health Organization's List of Essential Medicines. Prostaglandin E2 works as well as prostaglandin E1 in babies. Dinoprostone has important effects in labor...
34 KB (3,565 words) - 20:10, 14 May 2024
Prostacyclin (redirect from Prostaglandin I2)
Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation...
20 KB (1,639 words) - 08:58, 22 December 2023
Cyclooxygenase (redirect from Prostaglandin-endoperoxide synthase)
Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes, EC 1.14.99.1)...
16 KB (1,779 words) - 11:08, 3 July 2024
Aspirin (section Prostaglandins and thromboxanes)
of Surgeons in London, showed aspirin suppressed the production of prostaglandins and thromboxanes. For this discovery he was awarded the 1982 Nobel Prize...
152 KB (16,417 words) - 06:03, 6 August 2024
especially similar to selective COX-2 inhibitors. Paracetamol inhibits prostaglandin synthesis by reducing the active form of COX-1 and COX-2 enzymes. This...
123 KB (12,177 words) - 11:09, 10 August 2024
enzymes are involved in the synthesis of key biological mediators, namely prostaglandins, which are involved in inflammation, and thromboxanes, which are involved...
110 KB (11,559 words) - 18:11, 8 August 2024
Misoprostol (category Prostaglandins)
cases, uterine rupture may occur. It is a prostaglandin analogue—specifically, a synthetic prostaglandin E1 (PGE1). Misoprostol was developed in 1973...
51 KB (4,767 words) - 15:29, 17 July 2024
Cyclooxygenase-1 (redirect from Prostaglandin-endoperoxide synthase 1)
Cyclooxygenase 1 (COX-1), also known as prostaglandin-endoperoxide synthase 1 (HUGO PTGS1), is an enzyme that in humans is encoded by the PTGS1 gene....
18 KB (2,122 words) - 12:15, 2 June 2024
administered intravenously to horses. A single dose has been shown to reduce prostaglandin E2 production and inflammatory exudate for up to 15 hours, although...
18 KB (1,685 words) - 21:57, 1 July 2024
Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost is a naturally occurring prostaglandin used in medicine to induce...
12 KB (1,134 words) - 18:55, 24 April 2024
antipyretic effects. It acts by inhibiting the body's production of prostaglandin. It was patented in 1967 and approved for medical use in 1980. Ketoprofen...
18 KB (1,848 words) - 13:53, 1 July 2024
growths in the intestinal tract. Overexpression of COX-2 produces excess prostaglandins, which have been shown to increase the possibility of colorectal cancer...
42 KB (4,944 words) - 11:56, 4 April 2024
swelling from inflammation. It works by inhibiting the production of prostaglandins, endogenous signaling molecules known to cause these symptoms. It does...
23 KB (2,294 words) - 14:58, 28 July 2024
non-selectively to block the prostaglandin synthesis by inhibition of prostaglandin G/H synthesis 1 and 2. Prostaglandin functions in the body as a messenger...
25 KB (2,264 words) - 23:10, 26 May 2024
period. Like other NSAIDs, it works by inhibiting the production of prostaglandins by decreasing the activity of the enzyme cyclooxygenase (COX). Ibuprofen...
60 KB (5,863 words) - 17:15, 10 August 2024
in animal fats. It is a precursor in the formation of leukotrienes, prostaglandins, and thromboxanes. Together with omega-3 fatty acids and other omega-6...
21 KB (1,900 words) - 21:15, 28 July 2024
citation needed] Lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the...
15 KB (1,360 words) - 06:26, 7 April 2024
involved in the production of chemicals in the body called prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would...
5 KB (408 words) - 12:35, 14 July 2024
; Wang, T. N.; Lue, F. (April 1995). "Duplex ultrasonography after prostaglandin E1 injection of the clitoris in a case of hyperreactio luteinalis". The...
14 KB (1,399 words) - 13:33, 18 July 2024
Prostaglandin E is a family of naturally occurring prostaglandins that are used as medications. Types include: Prostaglandin E1 also known as alprostadil...
5 KB (148 words) - 21:50, 4 March 2021
Prostaglandin analogues are a class of drugs that bind to a prostaglandin receptor. Wider use of prostaglandin analogues is limited by unwanted side effects...
3 KB (342 words) - 21:37, 11 July 2024
Bimatoprost (category Prostaglandins)
during pregnancy or breastfeeding is generally not recommended. It is a prostaglandin analog and works by increasing the outflow of aqueous fluid from the...
15 KB (1,239 words) - 03:34, 5 August 2024
action by reducing the production of inflammatory mediators called prostaglandins. It is metabolized by the liver to inactive metabolites. Naproxen was...
34 KB (3,174 words) - 04:50, 18 July 2024
characterized by a fast onset of action. It works by blocking the production of prostaglandins (a chemical associated with pain), thereby relieving pain and inflammation...
18 KB (1,753 words) - 20:40, 17 July 2024
action of cyclooxygenase (COX) that is involved in the production of prostaglandins (PG) which is accountable for pain, swelling, inflammation and fever...
7 KB (445 words) - 15:09, 7 November 2023
Misoprostol Prostaglandin E1 (alprostadil) Prostaglandin E2 (dinoprostone) Treprostinil Antagonists: AH-6809 PF-04418948 TG 4-155 EP3Tooltip Prostaglandin EP3...
95 KB (11,044 words) - 15:17, 10 August 2024
10–20 μg of prostaglandin E1, with evaluations of the arterial flow every five minutes for 25–30 min (see image). The use of prostaglandin E1 is contraindicated...
68 KB (7,128 words) - 18:29, 30 July 2024
breastfeeding. Diclofenac is believed to work by decreasing the production of prostaglandins, like other drugs in this class. In 2021, diclofenac was the 61st most...
58 KB (5,599 words) - 23:32, 10 June 2024