Protamines are small, arginine-rich, nuclear proteins that replace histones late in the haploid phase of spermatogenesis and are believed essential for...
18 KB (2,042 words) - 23:50, 4 April 2024
Protamine sulfate is a medication that is used to reverse the effects of heparin. It is specifically used in heparin overdose, in low molecular weight...
14 KB (1,419 words) - 18:49, 28 June 2024
NPH insulin (redirect from Neutral protamine Hagedorn)
Neutral Protamine Hagedorn (NPH) insulin, also known as isophane insulin, is an intermediate-acting insulin given to help control blood sugar levels in...
11 KB (905 words) - 23:37, 11 September 2024
prior exposure to protamine, such as those who have had a previous vasectomy (protamine is contained in sperm) or diabetics (protamine is contained in neutral...
34 KB (4,040 words) - 09:37, 26 September 2024
be neutralized, protamine is used to neutralize heparin by binding to it. Animal and in vitro studies have demonstrated that protamine neutralizes the...
27 KB (3,060 words) - 14:59, 21 August 2024
Insulin aspart (redirect from Insulin aspart protamine)
which contains 30% insulin aspart and 70% insulin aspart protamine. The insulin aspart protamine portion is a crystalline form of insulin aspart, which...
24 KB (1,877 words) - 21:09, 21 September 2024
first scientist to isolate nucleic acid in 1869. Miescher also identified protamine and made several other discoveries. Miescher had isolated various phosphate-rich...
13 KB (1,490 words) - 19:13, 27 May 2024
irritation. He came upon protamine, a protein isolated from fish sperm. Hagedorn discovered that the addition of protamine to insulin caused the insulin...
3 KB (356 words) - 09:29, 4 July 2024
range. It is still used as an alternative to protamine sulfate for patients who are sensitive to protamine, and at least one surgical center has gone back...
5 KB (447 words) - 10:47, 16 September 2024
Protamine 1 is a protein that in humans is encoded by the PRM1 gene. GRCh38: Ensembl release 89: ENSG00000175646 – Ensembl, May 2017 "Human PubMed Reference:"...
4 KB (449 words) - 10:47, 11 April 2024
was split into several entries (including 2.7.11.1) in 2005. 2.7.11.70 "protamine kinase" was merged into 2.7.11.1 in 2004. 2.7.11.- is the generic level...
14 KB (1,210 words) - 13:35, 14 June 2024
adding protamine to insulin prolongs the duration of action of insulin 1946 Nordisk formulates Isophane porcine insulin aka Neutral Protamine Hagedorn...
108 KB (11,440 words) - 15:04, 26 September 2024
subsequently themselves replaced by protamines. TNPs in humans include TNP1 and TNP2. Chromatin Histone Protamine Sperm Spermatogenesis Spermiogenesis...
1 KB (85 words) - 02:12, 8 July 2022
Mogielnicki, Andrzej (2016). "The toxicology of heparin reversal with protamine: Past, present and future". Expert Opinion on Drug Metabolism & Toxicology...
46 KB (5,032 words) - 09:46, 11 August 2024
testis-specific proteins that show the highest level of expression are protamines. There are two phases in which the testes grow substantially. These are...
61 KB (6,239 words) - 20:50, 22 August 2024
efficient method for precipitating out RuBisCO involves the usage of protamine sulfate solution. Other existing methods for depleting RuBisCO and studying...
59 KB (6,522 words) - 18:16, 20 August 2024
Kar family of proteins, as well as a protamine, are required for the fusion of nuclear membranes. The protamine Prm3 is located on the outer surface of...
19 KB (2,272 words) - 05:23, 25 October 2023
following cardiopulmonary bypass procedures where heparin is reversed using protamine intraoperatively. In instances where a patient develops bleeding due to...
16 KB (2,008 words) - 16:59, 19 July 2024
Polyploidization Structures Telomere: Telomere-binding protein (TINF2) Protamine See also Extrachromosomal DNA Plasmid List of organisms by chromosome...
19 KB (1,963 words) - 06:04, 2 October 2024
NSAIDs. Other relatively common causes include chemotherapy, vaccines, protamine and herbal preparations. Some medications (vancomycin, morphine, x-ray...
58 KB (6,226 words) - 03:59, 9 September 2024
B1 BOVINE INSULIN 2omg: Structure of human insulin cocrystallized with protamine and urea 2omh: Structure of human insulin cocrystallized with ARG-12 peptide...
121 KB (13,799 words) - 18:31, 13 September 2024
have been used to improve transduction efficiency such as polybrene, protamine sulfate, retronectin, and DEAE Dextran. Gene therapy: Correcting genetic...
12 KB (1,431 words) - 21:03, 1 July 2024
Heparin sodium Phytomenadione Protamine sulfate Tranexamic acid Warfarin Complementary: Desmopressinα Heparin sodiumα Protamine sulfateα Warfarinα Deferasirox...
67 KB (4,835 words) - 05:59, 17 August 2024
which includes insulin glargine, do not appear much better than neutral protamine Hagedorn (NPH) insulin, but do have a greater cost, making them, as of...
20 KB (1,637 words) - 08:06, 7 September 2024
Polyploidization Structures Telomere: Telomere-binding protein (TINF2) Protamine See also Extrachromosomal DNA Plasmid List of organisms by chromosome...
8 KB (586 words) - 20:00, 24 October 2023
case, anti-Xa units can be measured and dosing adjusted accordingly. Protamine sulfate is less effective at reversing enoxaparin compared to heparin...
22 KB (1,681 words) - 21:53, 11 September 2024
liver disease, and stroke), severe liver disease, or severe hypertension. Protamine sulfate has been given to counteract the anticoagulant effect of heparin...
77 KB (7,855 words) - 18:45, 29 August 2024
States in July 2021, and in the European Union in March 2018. NPH (Neutral Protamine Hagedorn) insulin is an intermediate-acting insulin with delayed absorption...
22 KB (2,828 words) - 19:32, 20 December 2023
Protamine 2 is a protein that in humans is encoded by the PRM2 gene. Protamines substitute for histones in the chromatin of sperm during the haploid phase...
4 KB (570 words) - 20:37, 29 January 2023
retained in sperm cells (where most but not all histones are replaced by protamines). Thus nucleosome positioning is to some degree inheritable. Recent studies...
161 KB (18,346 words) - 02:11, 20 August 2024