Proteoglycans are proteins that are heavily glycosylated. The basic proteoglycan unit consists of a "core protein" with one or more covalently attached...
8 KB (835 words) - 16:01, 3 December 2023
Heparan sulfate (redirect from Heparan sulfate proteoglycan)
polysaccharide found in all animal tissues. It occurs as a proteoglycan (HSPG, i.e. Heparan Sulfate ProteoGlycan) in which two or three HS chains are attached in...
36 KB (4,151 words) - 06:37, 27 May 2024
Proteoglycan 4 or lubricin is a proteoglycan that in humans is encoded by the PRG4 gene. It acts as a joint/boundary lubricant. Lubricin is present in...
32 KB (3,667 words) - 17:44, 10 April 2024
CSPG4 (redirect from Melanoma-associated chondroitin sulfate proteoglycan)
Chondroitin sulfate proteoglycan 4, also known as melanoma-associated chondroitin sulfate proteoglycan (MCSP) or neuron-glial antigen 2 (NG2), is a chondroitin...
12 KB (1,501 words) - 04:42, 25 December 2023
Extracellular matrix (section Proteoglycans)
extracellular matrix proteins to form proteoglycans (hyaluronic acid is a notable exception; see below). Proteoglycans have a net negative charge that attracts...
36 KB (4,084 words) - 09:22, 12 August 2024
Neural/glial antigen 2, or NG2, is a rat integral membrane proteoglycan found in the plasma membrane of many diverse cell types. Homologous proteins in...
6 KB (882 words) - 01:35, 28 June 2024
In enzymology, a N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase (EC 2.4.1.226) is an enzyme that catalyzes the chemical reaction...
3 KB (309 words) - 18:17, 23 January 2024
than muscle. The matrix of cartilage is made up of glycosaminoglycans, proteoglycans, collagen fibers and, sometimes, elastin. It usually grows quicker than...
34 KB (3,824 words) - 06:19, 27 July 2024
Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase (EC 2.4.1.223, alpha-N-acetylglucosaminyltransferase I, alpha1...
3 KB (278 words) - 18:40, 23 January 2024
articular cartilage integrity as it is part of the proteoglycan molecules. The cartilage proteoglycan synthesis can speed up as chondroitin is going through...
2 KB (255 words) - 19:10, 27 March 2024
In enzymology, a N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase (EC 2.4.1.225) is an enzyme that catalyzes the chemical reaction...
2 KB (250 words) - 18:17, 23 January 2024
including: 3% cartilage oligomeric matrix protein, 1–2% elastin, 1–5% proteoglycans, 0.2% inorganic components such as copper, manganese, and calcium. Although...
46 KB (5,162 words) - 15:47, 20 August 2024
Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase (EC 2.4.1.224, alpha-N-acetylglucosaminyltransferase II...
3 KB (355 words) - 18:40, 23 January 2024
Glucuronylgalactosylproteoglycan 4-b-N-acetylgalactosaminyltransferase (redirect from UDP-N-acetyl-D-galactosamine:D-glucuronyl-1,3-beta-D-galactosyl-proteoglycan beta-1,4-N-acetylgalactosaminyltransferase)
I, UDP-N-acetyl-D-galactosamine:D-glucuronyl-1,3-beta-D-galactosyl-proteoglycan beta-1,4-N-acetylgalactosaminyltransferase) is an enzyme with systematic...
2 KB (219 words) - 18:40, 23 January 2024
(ACAN), also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1, is a protein that in humans is encoded...
16 KB (1,985 words) - 03:45, 12 May 2024
Chondroitin sulfate proteoglycans (CSPGs) are proteoglycans consisting of a protein core and a chondroitin sulfate side chain. They are known to be structural...
15 KB (1,778 words) - 11:24, 12 August 2023
studied until recently. Like the chondroitin sulfate proteoglycans, keratan sulfate proteoglycan (KSPG) production is up regulated in reactive astrocytes...
29 KB (3,575 words) - 10:07, 2 June 2024
matrix proteoglycan that is present in a variety of human tissues. It is encoded by the VCAN gene. Versican is a large chondroitin sulfate proteoglycan with...
19 KB (2,427 words) - 15:21, 24 January 2024
Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase (EC 2.4.1.175, N-acetylgalactosaminyltransferase II,...
3 KB (298 words) - 18:40, 23 January 2024
Tsukushi (protein) (redirect from Tsukushi, small leucine rich proteoglycan)
tsukushin is an extracellular matrix protein of the small leucine rich proteoglycan (SLRP) family. In humans it is encoded by the TSKU gene. Tsukushi is...
2 KB (242 words) - 00:53, 4 March 2023
play a role in the IL-1 degradation of proteoglycans and collagen; lysosomal enzymes that cause proteoglycans to dissociate from hyaluronic acid; elastase;...
14 KB (1,148 words) - 18:01, 27 February 2023
and/or inflammation may cause epithelial matrix changes. The absence of proteoglycans, which are glycosaminoglycan chains attached to protein, may contribute...
17 KB (1,779 words) - 23:31, 2 June 2024
body. The collagen fibers are embedded in a network woven from proteoglycans. A proteoglycan molecule consists of a small core protein with many carbohydrate...
5 KB (629 words) - 12:23, 11 December 2023
forming proteoglycans. Keratan sulfate which may modify core proteins through N-linked glycosylation or O-linked glycosylation of the proteoglycan Hyaluronic...
23 KB (2,639 words) - 09:17, 29 July 2024
basic protein, often shortened to major basic protein (MBP; also called Proteoglycan 2 (PRG2)) is encoded in humans by the PRG2 gene. The protein encoded...
13 KB (1,515 words) - 04:45, 27 January 2024
maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans. Although the word chondroblast is commonly used to describe an immature...
15 KB (1,815 words) - 21:24, 20 April 2024
Antioxidants PRPP Nucleotides Nucleic acids Proteins Glycoproteins & proteoglycans Chlorophylls MEP MVA Acetyl -CoA Polyketides Terpenoid backbones Terpenoids...
49 KB (5,446 words) - 08:06, 23 August 2024
type of cartilage has varying concentrations of components such as proteoglycans, collagen and water which determine its functional properties and location...
30 KB (3,493 words) - 12:58, 2 June 2024
Decorin (category Proteoglycans)
Decorin is a proteoglycan that is on average 90 - 140 kilodaltons (kDa) in molecular weight. It belongs to the small leucine-rich proteoglycan (SLRP) family...
17 KB (1,949 words) - 09:42, 21 December 2023
ligament desmitis, commonly called DSLD, also known as equine systemic proteoglycan accumulation (ESPA), is a systemic disease of the connective tissue of...
4 KB (464 words) - 15:36, 19 September 2023