• Thumbnail for RTI-274
    RTI(-4229)-274, or 2β-((3,4-Methyl​enedioxy​phenoxy)methyl)-3α-(4-fluorophenyl)​nortropane is a phenyltropane homologue of paroxetine developed by the...
    6 KB (477 words) - 05:59, 21 June 2022
  • Thumbnail for List of phenyltropanes
    (c.f. RTI-29). Many of the compounds were first elucidated in published material by the Research Triangle Institute and are thus named with "RTI" serial-numbers...
    168 KB (5,647 words) - 19:32, 1 June 2024
  • Thumbnail for Tesofensine
    35428 RTI-31 RTI-32 RTI-51 RTI-55 RTI-83 (3,4-Disubstituted Phenyl)-tropanes Dichloropane RTI-112 RTI-353 Arylcarboxy RTI-113 RTI-120 Carboxyalkyl RTI-121...
    16 KB (1,763 words) - 20:54, 16 August 2024
  • Thumbnail for RTI-177
    RTI(-4229)-177 (2β-(3-phenylisoxazol-5-yl)-3β-(4-chlorophenyl)tropane, β-CPPIT) is a synthetic stimulant drug from the phenyltropane family, which acts...
    6 KB (458 words) - 16:49, 14 April 2022
  • Thumbnail for RTI-336
    RTI(-4229)-336, (LS-193,309, (−)-2β-(3-(4-methylphenyl)isoxazol-5-yl)-3β-(4-chlorophenyl)tropane) is a phenyltropane derivative which acts as a potent...
    8 KB (637 words) - 00:42, 27 December 2023
  • Thumbnail for RTI-55
    RTI(-4229)-55, also called RTI-55 or iometopane, is a phenyltropane-based psychostimulant used in scientific research and in some medical applications...
    10 KB (983 words) - 17:54, 4 February 2024
  • Thumbnail for RTI-31
    (–)-2β-Carbomethoxy-3β-(4'-chlorophenyl)tropane (RTI-4229-31) is a synthetic analog of cocaine that acts as a stimulant. Semi-synthesis of this compound...
    8 KB (630 words) - 01:42, 4 February 2024
  • Thumbnail for RTI-353
    RTI(-4229)-353 is a phenyltropane derived drug which acts as an SSRI. Tamagnan et al. also made some phenyltropanes with high activity and selectivity...
    2 KB (146 words) - 17:55, 4 February 2024
  • Thumbnail for RTI-51
    (–)-2β-Carbomethoxy-3β-(4-bromophenyl)tropane (RTI-4229-51, bromopane) is a semi-synthetic alkaloid in the phenyltropane group of psychostimulant compounds...
    7 KB (544 words) - 00:37, 29 November 2023
  • Thumbnail for RTI-112
    RTI(-4229)-112 (2β-carbomethoxy-3β-(3-methyl-4-chlorophenyl)tropane) is a synthetic stimulant drug from the phenyltropane family. In contrast to RTI-113...
    7 KB (602 words) - 01:42, 4 February 2024
  • Thumbnail for RTI-171
    (–)-2β-(3-Methylisoxazol-5-yl)-3β-(p-tolyl)tropane (RTI-4229-171) is a phenyltropane derivative which acts as a selective dopamine reuptake inhibitor...
    2 KB (158 words) - 06:49, 11 November 2023
  • Thumbnail for RTI-32
    (RTI-4229-32, tolpane) is a phenyltropane-based cocaine analogue that has similar properties in vitro to related drugs such as RTI-31....
    2 KB (129 words) - 18:15, 21 November 2022
  • Thumbnail for RTI-229
    RTI-229, also known as (–)-3β-(4-iodophenyl)tropane-2β-pyrrolidine carboxamide and RTI-4229-229, is a potent and long-lasting stimulant drug which was...
    4 KB (344 words) - 10:26, 23 February 2024
  • Thumbnail for RTI-126
    RTI-126 (RTI-4229-126 or (–)-2β-(1,2,4-oxadiazol-5-methyl)-3β-phenyltropane) is a phenyltropane derivative which acts as a potent monoamine reuptake inhibitor...
    4 KB (372 words) - 23:00, 22 September 2022
  • Thumbnail for RTI-352
    RTI-352 is a phenyltropane that is used as a radiolabeling ligand for the DAT. RTI-352 is a geometric isomer of RTI-55 (β-CIT). Based on X-ray crystallography...
    2 KB (118 words) - 22:49, 6 May 2023
  • Thumbnail for List of cocaine analogues
    RTI-31 RTI-32 RTI-51 RTI-112 RTI-113 RTI-120 RTI-121 (IPCIT) RTI-126 RTI-150 RTI-177 RTI-229 RTI-336 RTI-354 RTI-371 RTI-386 Salicylmethylecgonine Tesofensine...
    111 KB (5,555 words) - 16:59, 8 June 2024
  • Thumbnail for RTI-121
    (RTI-4229-121, IPCIT) is a stimulant drug used in scientific research, which was developed in the early 1990s. RTI-121 is a phenyltropane...
    7 KB (602 words) - 17:55, 4 February 2024
  • Thumbnail for Phenyltropane
    cocaine. RTI-336 is an interesting example of a phenyltropane that is being explored in the context of a treatment for cocaine addiction. RTI-336 is a...
    21 KB (2,077 words) - 07:54, 11 July 2023
  • Thumbnail for NS-2359
    35428 RTI-31 RTI-32 RTI-51 RTI-55 RTI-83 (3,4-Disubstituted Phenyl)-tropanes Dichloropane RTI-112 RTI-353 Arylcarboxy RTI-113 RTI-120 Carboxyalkyl RTI-121...
    3 KB (275 words) - 21:05, 27 May 2024
  • Thumbnail for Troparil
    RTI-31 RTI-32 RTI-51 RTI-112 RTI-113 RTI-120 RTI-121 (IPCIT) RTI-126 RTI-150 RTI-177 RTI-229 RTI-336 RTI-354 RTI-371 RTI-386 Salicylmethylecgonine Tesofensine...
    11 KB (1,036 words) - 20:20, 18 July 2023
  • Thumbnail for RTI-83
    RTI-83 ((–)-2β-carbomethoxy-3β-(4-ethylphenyl)tropane) is a phenyltropane derivative which represents a rare example of an SDRI or serotonin-dopamine...
    6 KB (452 words) - 00:57, 29 November 2023
  • Thumbnail for PCP site 2
    site, identified with [125I]RTI-55, in membranes prepared from whole rat brain minus caudate". J. Pharmacol. Exp. Ther. 274 (1): 385–95. PMID 7616423....
    6 KB (378 words) - 11:29, 28 January 2024
  • Thumbnail for Ioflupane (123I)
    RTI-31 RTI-32 RTI-51 RTI-112 RTI-113 RTI-120 RTI-121 (IPCIT) RTI-126 RTI-150 RTI-177 RTI-229 RTI-336 RTI-354 RTI-371 RTI-386 Salicylmethylecgonine Tesofensine...
    11 KB (758 words) - 03:59, 14 April 2024
  • Thumbnail for RTI-150
    RTI(-4229)-150, ((−)-2β-Carbocyclobutoxy-3β-(4-methylphenyl)tropane) is a phenyltropane derivative which acts as a potent dopamine reuptake inhibitor...
    3 KB (313 words) - 10:42, 7 October 2023
  • Thumbnail for Dichloropane
    Dichloropane (redirect from RTI-111)
    Dichloropane ((−)-2β-Carbomethoxy-3β-(3,4-dichlorophenyl)tropane, RTI-111, O-401) is a stimulant of the phenyltropane class that acts as a...
    4 KB (296 words) - 09:36, 13 December 2023
  • Thumbnail for Brasofensine
    35428 RTI-31 RTI-32 RTI-51 RTI-55 RTI-83 (3,4-Disubstituted Phenyl)-tropanes Dichloropane RTI-112 RTI-353 Arylcarboxy RTI-113 RTI-120 Carboxyalkyl RTI-121...
    6 KB (527 words) - 06:09, 13 February 2024
  • Thumbnail for RTI-371
    RTI-371 and the closely related compound RTI-370 failed to produce locomotor stimulation in mice. In addition to this, in drug substitution tests RTI-370...
    2 KB (190 words) - 13:38, 18 May 2023
  • Thumbnail for RTI-120
    (–)-2β-Carbophenoxy-3β-(p-tolyl)tropane (RTI-4229-120) is a phenyltropane derivative which acts as a reasonably selective dopamine reuptake inhibitor...
    3 KB (241 words) - 06:16, 27 January 2022
  • Thumbnail for Altropane
    RTI-31 RTI-32 RTI-51 RTI-112 RTI-113 RTI-120 RTI-121 (IPCIT) RTI-126 RTI-150 RTI-177 RTI-229 RTI-336 RTI-354 RTI-371 RTI-386 Salicylmethylecgonine Tesofensine...
    4 KB (266 words) - 20:05, 16 December 2023
  • Thumbnail for FE-β-CPPIT
    RTI-31 RTI-32 RTI-51 RTI-112 RTI-113 RTI-120 RTI-121 (IPCIT) RTI-126 RTI-150 RTI-177 RTI-229 RTI-336 RTI-354 RTI-371 RTI-386 Salicylmethylecgonine Tesofensine...
    1 KB (50 words) - 04:39, 25 March 2024