Rasagiline, sold under the brand name Azilect among others, is a medication which is used in the treatment of Parkinson's disease. It is used as a monotherapy...
90 KB (8,896 words) - 18:06, 18 October 2024
imipramine, desipramine), monoamine oxidase inhibitors (MAOIs) (e.g., rasagiline), serotonin antagonists and reuptake inhibitors (SARIs) (e.g., nefazodone)...
4 KB (360 words) - 02:54, 18 December 2022
is less selective for MAO-B inhibition than AGN-1135 (racemic rasagiline) or rasagiline. In addition to its MAOI activity, SU-11739 has been reported...
7 KB (534 words) - 07:05, 1 October 2024
racemic rasagiline or as N-propargyl-1-aminoindane) is a monoamine oxidase inhibitor (MAOI) that was never marketed. It is the racemic form of rasagiline and...
4 KB (212 words) - 02:30, 15 September 2024
Antagonists of MAEs, like EPPTB (a known TAAR1 antagonist), 3-F-BPAP, and rasagiline, have been identified. A few endogenous MAEs have been identified, including...
54 KB (5,655 words) - 03:41, 30 September 2024
pharmacologically active and is an active metabolite of the antiparkinsonian agent rasagiline. Through its (R)-enantiomer (R)-1-aminoindane, 1-aminoindane has pharmacological...
10 KB (739 words) - 05:54, 14 September 2024
MAO-B inhibitor and antiparkinsonian agent rasagiline ((R)-N-propargyl-1-aminoindan). In contrast to rasagiline, it lacks significant monoamine oxidase inhibition...
9 KB (692 words) - 09:49, 6 September 2024
Management of Parkinson's disease (section Rasagiline)
B propargyl amine inhibitor rasagiline (N-propargyl-1-R-aminoindan, Azilect((R))). The oral bioavailability of rasagiline is 35%, it reaches T(max) after...
71 KB (8,447 words) - 17:36, 19 February 2024
Parkinson's disease. It was developed from structural modification of rasagiline. The drug acts as a reversible acetylcholinesterase and butyrylcholinesterase...
6 KB (523 words) - 22:17, 17 August 2024
more potent than D-deprenyl. AGN-1135 (racemic rasagiline) SU-11739 (racemic N-methylated rasagiline) Parnham, M. J. (1993). "The History of l-Deprenyl"...
7 KB (517 words) - 21:14, 17 October 2024
Nefopam Nikethamide Nomifensine O-2172 Oxaprotiline PNU-99,194 PRC200-SS Rasagiline Rauwolscine Rubidium chloride Setazindol Tametraline Tandamine Thiopropamine...
181 KB (19,613 words) - 04:19, 10 October 2024
treatment, e.g. in multiple sclerosis Livedo reticularis associated with rasagiline Methylphenidate and dextroamphetamine-induced peripheral vasculopathy...
25 KB (2,529 words) - 17:34, 12 September 2024
disease. There is evidence that selegiline may be more effective than rasagiline in the treatment of Parkinson's disease. This may be due to pharmacological...
208 KB (20,184 words) - 23:53, 18 October 2024
amphetamine metabolites or have associated cardiovascular effects, such as rasagiline, have also been developed and introduced. Because selegiline metabolizes...
62 KB (6,009 words) - 01:58, 22 September 2024
Nefopam Nikethamide Nomifensine O-2172 Oxaprotiline PNU-99,194 PRC200-SS Rasagiline Rauwolscine Rubidium chloride Setazindol Tametraline Tandamine Thiopropamine...
165 KB (15,851 words) - 21:46, 14 October 2024
moclobemide and clorgyline, and MAOB selective agents such as selegiline and rasagiline, as well as the harmala alkaloids like harmine, harmaline, tetrahydroharmine...
23 KB (2,278 words) - 09:55, 28 September 2024
Parkinson's disease (PD), and several anti-apoptotic PD drugs, such as rasagiline, function by preventing the nuclear translocation of GAPDH. It is proposed...
33 KB (3,786 words) - 00:05, 30 July 2024
Propofol Prothipendyl Protriptyline Proparacaine Quetiapine Ramelteon Rasagiline Reboxetine Ribavirin Rimonabant Risperidone Rivastigmine Rofecoxib Ropinirole...
26 KB (1,722 words) - 21:40, 3 October 2024
T3 Technion Technology Transfer (section Rasagiline)
and approval of the IP and business aspects of agreements with industry Rasagiline is a drug to treat Parkinson's disease discovered by Prof. Moussa B.H...
16 KB (1,426 words) - 07:26, 28 June 2024
Nefopam Nikethamide Nomifensine O-2172 Oxaprotiline PNU-99,194 PRC200-SS Rasagiline Rauwolscine Rubidium chloride Setazindol Tametraline Tandamine Thiopropamine...
58 KB (21,548 words) - 19:20, 8 October 2024
EPPTB reversing its MAE effects, among other findings. Another compound, rasagiline, has likewise been found to reverse the effects of MAEs, and has been...
30 KB (2,838 words) - 01:18, 16 September 2024
Nefopam Nikethamide Nomifensine O-2172 Oxaprotiline PNU-99,194 PRC200-SS Rasagiline Rauwolscine Rubidium chloride Setazindol Tametraline Tandamine Thiopropamine...
156 KB (15,356 words) - 20:21, 18 October 2024
both monoamine oxidase (MAO) B inhibitors l-deprenyl (Selegiline) and rasagiline (Azilect) as anti-Parkinson drugs which possess neuroprotective activities...
17 KB (1,821 words) - 17:40, 12 September 2024
"Essential difference between the pharmacological spectrum of (-)-deprenyl and rasagiline". Pharmacological Reports. 66 (3): 453–458. doi:10.1016/j.pharep.2013...
19 KB (1,485 words) - 00:57, 20 August 2024
adjunct therapy to levodopa. MAO-B inhibitors (safinamide, selegiline and rasagiline) increase the amount of dopamine in the basal ganglia by inhibiting the...
175 KB (19,045 words) - 07:39, 18 October 2024
Nefopam Nikethamide Nomifensine O-2172 Oxaprotiline PNU-99,194 PRC200-SS Rasagiline Rauwolscine Rubidium chloride Setazindol Tametraline Tandamine Thiopropamine...
20 KB (1,745 words) - 12:05, 2 October 2024
Nefopam Nikethamide Nomifensine O-2172 Oxaprotiline PNU-99,194 PRC200-SS Rasagiline Rauwolscine Rubidium chloride Setazindol Tametraline Tandamine Thiopropamine...
35 KB (3,893 words) - 21:34, 19 August 2024
developed in the context of anti-Parkinsonian drugs as a metabolite of rasagiline and as a tool to be used in psychotherapy. Deaths related to their toxic...
7 KB (535 words) - 22:27, 1 September 2024
in the causation and progression of macular degeneration and melanoma. Rasagiline, an important monotherapy drug in Parkinson's disease, has melanin binding...
64 KB (6,759 words) - 04:33, 24 September 2024
Levomethamphetamine Phenylpropylaminopentane (PPAP) Antagonists 3-F-BPAP EPPTB Rasagiline See also: Receptor/signaling modulators • Monoamine releasing agents •...
59 KB (20,579 words) - 18:08, 9 October 2024