• Thumbnail for Rasagiline
    Rasagiline, sold under the brand name Azilect among others, is a medication which is used in the treatment of Parkinson's disease. It is used as a monotherapy...
    90 KB (8,896 words) - 18:06, 18 October 2024
  • imipramine, desipramine), monoamine oxidase inhibitors (MAOIs) (e.g., rasagiline), serotonin antagonists and reuptake inhibitors (SARIs) (e.g., nefazodone)...
    4 KB (360 words) - 02:54, 18 December 2022
  • Thumbnail for SU-11739
    is less selective for MAO-B inhibition than AGN-1135 (racemic rasagiline) or rasagiline. In addition to its MAOI activity, SU-11739 has been reported...
    7 KB (534 words) - 07:05, 1 October 2024
  • Thumbnail for AGN-1135
    racemic rasagiline or as N-propargyl-1-aminoindane) is a monoamine oxidase inhibitor (MAOI) that was never marketed. It is the racemic form of rasagiline and...
    4 KB (212 words) - 02:30, 15 September 2024
  • Thumbnail for Monoaminergic activity enhancer
    Antagonists of MAEs, like EPPTB (a known TAAR1 antagonist), 3-F-BPAP, and rasagiline, have been identified. A few endogenous MAEs have been identified, including...
    54 KB (5,655 words) - 03:41, 30 September 2024
  • Thumbnail for 1-Aminoindane
    pharmacologically active and is an active metabolite of the antiparkinsonian agent rasagiline. Through its (R)-enantiomer (R)-1-aminoindane, 1-aminoindane has pharmacological...
    10 KB (739 words) - 05:54, 14 September 2024
  • Thumbnail for (R)-1-Aminoindan
    MAO-B inhibitor and antiparkinsonian agent rasagiline ((R)-N-propargyl-1-aminoindan). In contrast to rasagiline, it lacks significant monoamine oxidase inhibition...
    9 KB (692 words) - 09:49, 6 September 2024
  • B propargyl amine inhibitor rasagiline (N-propargyl-1-R-aminoindan, Azilect((R))). The oral bioavailability of rasagiline is 35%, it reaches T(max) after...
    71 KB (8,447 words) - 17:36, 19 February 2024
  • Thumbnail for Ladostigil
    Parkinson's disease. It was developed from structural modification of rasagiline. The drug acts as a reversible acetylcholinesterase and butyrylcholinesterase...
    6 KB (523 words) - 22:17, 17 August 2024
  • Thumbnail for Deprenyl
    more potent than D-deprenyl. AGN-1135 (racemic rasagiline) SU-11739 (racemic N-methylated rasagiline) Parnham, M. J. (1993). "The History of l-Deprenyl"...
    7 KB (517 words) - 21:14, 17 October 2024
  • Thumbnail for Cocaine
    Nefopam Nikethamide Nomifensine O-2172 Oxaprotiline PNU-99,194 PRC200-SS Rasagiline Rauwolscine Rubidium chloride Setazindol Tametraline Tandamine Thiopropamine...
    181 KB (19,613 words) - 04:19, 10 October 2024
  • Thumbnail for Livedo reticularis
    treatment, e.g. in multiple sclerosis Livedo reticularis associated with rasagiline Methylphenidate and dextroamphetamine-induced peripheral vasculopathy...
    25 KB (2,529 words) - 17:34, 12 September 2024
  • Thumbnail for Selegiline
    disease. There is evidence that selegiline may be more effective than rasagiline in the treatment of Parkinson's disease. This may be due to pharmacological...
    208 KB (20,184 words) - 23:53, 18 October 2024
  • Thumbnail for Levoamphetamine
    amphetamine metabolites or have associated cardiovascular effects, such as rasagiline, have also been developed and introduced. Because selegiline metabolizes...
    62 KB (6,009 words) - 01:58, 22 September 2024
  • Thumbnail for MDMA
    Nefopam Nikethamide Nomifensine O-2172 Oxaprotiline PNU-99,194 PRC200-SS Rasagiline Rauwolscine Rubidium chloride Setazindol Tametraline Tandamine Thiopropamine...
    165 KB (15,851 words) - 21:46, 14 October 2024
  • Thumbnail for Dopaminergic
    moclobemide and clorgyline, and MAOB selective agents such as selegiline and rasagiline, as well as the harmala alkaloids like harmine, harmaline, tetrahydroharmine...
    23 KB (2,278 words) - 09:55, 28 September 2024
  • Thumbnail for Glyceraldehyde 3-phosphate dehydrogenase
    Parkinson's disease (PD), and several anti-apoptotic PD drugs, such as rasagiline, function by preventing the nuclear translocation of GAPDH. It is proposed...
    33 KB (3,786 words) - 00:05, 30 July 2024
  • Propofol Prothipendyl Protriptyline Proparacaine Quetiapine Ramelteon Rasagiline Reboxetine Ribavirin Rimonabant Risperidone Rivastigmine Rofecoxib Ropinirole...
    26 KB (1,722 words) - 21:40, 3 October 2024
  • Thumbnail for T3 Technion Technology Transfer
    and approval of the IP and business aspects of agreements with industry Rasagiline is a drug to treat Parkinson's disease discovered by Prof. Moussa B.H...
    16 KB (1,426 words) - 07:26, 28 June 2024
  • Thumbnail for Adderall
    Nefopam Nikethamide Nomifensine O-2172 Oxaprotiline PNU-99,194 PRC200-SS Rasagiline Rauwolscine Rubidium chloride Setazindol Tametraline Tandamine Thiopropamine...
    58 KB (21,548 words) - 19:20, 8 October 2024
  • Thumbnail for Benzofuranylpropylaminopentane
    EPPTB reversing its MAE effects, among other findings. Another compound, rasagiline, has likewise been found to reverse the effects of MAEs, and has been...
    30 KB (2,838 words) - 01:18, 16 September 2024
  • Thumbnail for Methamphetamine
    Nefopam Nikethamide Nomifensine O-2172 Oxaprotiline PNU-99,194 PRC200-SS Rasagiline Rauwolscine Rubidium chloride Setazindol Tametraline Tandamine Thiopropamine...
    156 KB (15,356 words) - 20:21, 18 October 2024
  • Thumbnail for Moussa B. H. Youdim
    both monoamine oxidase (MAO) B inhibitors l-deprenyl (Selegiline) and rasagiline (Azilect) as anti-Parkinson drugs which possess neuroprotective activities...
    17 KB (1,821 words) - 17:40, 12 September 2024
  • Thumbnail for Desmethylselegiline
    "Essential difference between the pharmacological spectrum of (-)-deprenyl and rasagiline". Pharmacological Reports. 66 (3): 453–458. doi:10.1016/j.pharep.2013...
    19 KB (1,485 words) - 00:57, 20 August 2024
  • Thumbnail for Parkinson's disease
    adjunct therapy to levodopa. MAO-B inhibitors (safinamide, selegiline and rasagiline) increase the amount of dopamine in the basal ganglia by inhibiting the...
    175 KB (19,045 words) - 07:39, 18 October 2024
  • Thumbnail for Α-Pyrrolidinopentiophenone
    Nefopam Nikethamide Nomifensine O-2172 Oxaprotiline PNU-99,194 PRC200-SS Rasagiline Rauwolscine Rubidium chloride Setazindol Tametraline Tandamine Thiopropamine...
    20 KB (1,745 words) - 12:05, 2 October 2024
  • Thumbnail for Crack cocaine
    Nefopam Nikethamide Nomifensine O-2172 Oxaprotiline PNU-99,194 PRC200-SS Rasagiline Rauwolscine Rubidium chloride Setazindol Tametraline Tandamine Thiopropamine...
    35 KB (3,893 words) - 21:34, 19 August 2024
  • Thumbnail for 2-Aminoindane
    developed in the context of anti-Parkinsonian drugs as a metabolite of rasagiline and as a tool to be used in psychotherapy. Deaths related to their toxic...
    7 KB (535 words) - 22:27, 1 September 2024
  • Thumbnail for Melanin
    in the causation and progression of macular degeneration and melanoma. Rasagiline, an important monotherapy drug in Parkinson's disease, has melanin binding...
    64 KB (6,759 words) - 04:33, 24 September 2024
  • Thumbnail for Dextroamphetamine
    Levomethamphetamine Phenylpropylaminopentane (PPAP) Antagonists 3-F-BPAP EPPTB Rasagiline See also: Receptor/signaling modulators • Monoamine releasing agents •...
    59 KB (20,579 words) - 18:08, 9 October 2024