In biochemistry, a ribonucleotide is a nucleotide containing ribose as its pentose component. It is considered a molecular precursor of nucleic acids....

Ribonucleotide reductase (RNR), also known as ribonucleoside diphosphate reductase, is an enzyme that catalyzes the formation of deoxyribonucleotides from...

Disodium 5'-ribonucleotides or I+G, E number E635, is a flavor enhancer which is synergistic with glutamates in creating the taste of umami. It is a mixture...

5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate. AICAR is an analog of adenosine monophosphate...

Other names Nicotinamide ribonucleoside 5′-phosphate Nicotinamide D-ribonucleotide β-Nicotinamide ribose monophosphate Nicotinamide nucleotide Identifiers...

chemical reaction ATP + (ribonucleotide)n + (ribonucleotide)m ⇌ {\displaystyle \rightleftharpoons } AMP + diphosphate + (ribonucleotide)n+m. Their three substrates...

reaction beta-nicotinamide D-ribonucleotide + H2O ⇌ {\displaystyle \rightleftharpoons } beta-nicotinate D-ribonucleotide + NH3 Thus, the two substrates...

removed to become a NDP, then is converted to a dNDP by an enzyme called ribonucleotide reductase, then a phosphate is added back to give a dNTP. A nitrogenous...

that catalyzes the chemical reaction a 2,4-dioxotetrahydropyrimidine D-ribonucleotide + diphosphate ⇌ {\displaystyle \rightleftharpoons } a 2,4-dioxotetrahydropyrimidine...

nucleobase molecule, also known as a nitrogenous base—and are termed ribonucleotides if the sugar is ribose, or deoxyribonucleotides if the sugar is deoxyribose...

Ribonucleotide reductase inhibitors are a family of anti-cancer drugs that interfere with the growth of tumor cells by blocking the formation of deoxyribonucleotides...

glycineamide ribonucleotide (GAR). GAR transformylase adds a formyl group onto the amino group of GAR, forming formylglycinamide ribonucleotide (FGAR). FGAR...

enzymology, an urate-ribonucleotide phosphorylase (EC 2.4.2.16) is an enzyme that catalyzes the chemical reaction urate D-ribonucleotide + phosphate ⇌ {\displaystyle...

In enzymology, a 5-(carboxyamino)imidazole ribonucleotide mutase (EC 5.4.99.18) is an enzyme that catalyzes the chemical reaction 5-carboxyamino-1-(5-...

Glycineamide ribonucleotide (or GAR) is a biochemical intermediate in the formation of purine nucleotides via inosine-5-monophosphate, and hence is a building...

In enzymology, a 5-(carboxyamino)imidazole ribonucleotide synthase (EC 6.3.4.18) is an enzyme that catalyzes the chemical reaction ATP +...

Calcium 5'-ribonucleotides is a mixture used as a flavor enhancer food additive. It listed as E number reference E634. This food additive is banned in...

another umami substance. This was the ribonucleotide IMP. In 1957, Akira Kuninaka realized that the ribonucleotide GMP present in shiitake mushrooms also...

The enzyme 3′-nucleotidase (EC 3.1.3.6) the reaction a 3′-ribonucleotide + H2O ⇌ {\displaystyle \rightleftharpoons } a ribonucleoside + phosphate This...

is an enzyme that catalyzes the chemical reaction ATP + nicotinate ribonucleotide ⇌ {\displaystyle \rightleftharpoons } diphosphate + deamido-NAD+ Thus...

Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2), also known as glycinamide ribonucleotide transformylase (GAR Tfase), is an enzyme with systematic name...

profile of embedded ribonucleotides, specifically ribonucleoside monophosphates (rNMPs), in genomic DNA. Embedded ribonucleotides are thought to be the...

Nicotinamide phosphoribosyltransferase (NAmPRTase or NAMPT), formerly known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin for its extracellular...

the pentose sugar ribose, and the nucleobase guanine; hence it is a ribonucleotide monophosphate. Guanosine monophosphate is commercially produced by microbial...

(CAIR) to 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide, ADP, and phosphate by phosphoribosylaminoimidazolesuccinocarboxamide...

adds a formyl group from 10-formyltetrahydrofolate to glycineamide ribonucleotide (GAR) in reaction EC 2.1.2.2: GAR + 10-formyltetrahydrofolate → FGAR...

belongs to the family of drugs called ribonucleotide reductase inhibitors. 3AP is a potent inhibitor of ribonucleotide reductase, the rate determining enzyme...

19) is an enzyme that catalyzes the chemical reaction nicotinate D-ribonucleotide + diphosphate + CO2 ⇌ {\displaystyle \rightleftharpoons } pyridine-2...

phosphates attached (dFdCDP) also has activity; it inhibits the enzyme ribonucleotide reductase (RNR), which is needed to create new DNA nucleotides. The...

complex structures of a chemotherapeutic target: human glycinamide ribonucleotide transformylase". Biochemistry. 44 (29): 9841–50. doi:10.1021/bi050307g...