of transcription 5B is a protein that in humans is encoded by the STAT5B gene. STAT5B orthologs have been identified in most placentals for which complete...

but can also be caused by defective post-receptor signal transduction (STAT5B), abnormalities of the IGF-1 gene or IGF-1 receptor. Secondary (acquired)...

matrix associated, signal transducer and activator of transcription 5b (STAT5B), protein kinase A regulatory subunit 1α (PRKAR1A), factor interacting with...

related proteins, STAT5A and STAT5B, which are part of the seven-membered STAT family of proteins. Though STAT5A and STAT5B are encoded by separate genes...

MSM to have multiple targets, both in vitro and in vivo, including STAT3, STAT5b, IGF-1R and VEGF, confirming the ability of MSM to suppress tumor initiation...

diagnosis sees that the following should be considered: CD25 deficiency STAT5B deficiency Severe combined immunodeficiency X linked thrombocytopenia Immunosuppressive...

pathway component gain promotes cell proliferation and survival unknown STAT5B STAT5B ~2–6% JAK-STAT signaling pathway component gain promotes cell proliferation...

mechanism suggests that growth hormones may phosphorylate with STAT5A and STAT5B, transcription factors that are a part of the Signal Transducer And Activator...

ENSG00000126561 STAT Known motif – In vivo/Misc source [889] YTTCYNRGAAHY STAT5B ENSG00000173757 STAT Known motif – In vivo/Misc source [890] ADTTCYHRGAAA...

SOCS4; SOCS5; SOCS6; SOCS7 SRC; SRMS STAT1; STAT2; STAT3; STAT4; STAT5A; STAT5B; STAT6 SUPT6H; SYK TEC; TENC1; TNS; TNS1; TNS3; TNS4; TXK VAV1; VAV2; VAV3...

NCOA1, NCOA2, NCOA3, POU2F1, RANBP9, RELA, SMAD3, SMARCD1, SMARCA4 STAT3, STAT5B, Thioredoxin, TRIM28, and YWHAH. Membrane glucocorticoid receptor Selective...

Dr. Nadeau and her laboratory discovered novel mechanisms of STAT5a and STAT5b transcriptional factors to help understand the human immune system. After...

that have been identified: STAT1, STAT2, STAT3, STAT4, STAT5 (STAT5A and STAT5B), and STAT6. STAT1 homodimers are involved in type II interferon signalling...

proteins. There are seven STAT proteins: STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B and STAT6. STAT proteins contain many different domains, each with a different...

also be caused by mutations in the STAT genes, particularly STAT5B and STAT1. Because STAT5B is involved in the formation of regulatory T cells, mutations...

IL12RB2 IL5RA PIK3R1 PPP2R4 PTK2 PTPN11 PTPN6 PRMT5 SH2B1 SHC1 SOCS3 STAT5A STAT5B STAM SOCS1 TEC TNFRSF1A VAV1 YES1 Prolactin signals through JAK2 are dependent...

acids unique to its C-terminal domain and is 96% similar to its homolog, STAT5b. The six functional domains and their corresponding amino acid positions...

GNB2L1 IL6ST, Grb2, IL2RB, IRS1, IL10RA, PTPN11, STAM2, STAT3, STAT5A, STAT5B, and TNFRSF1A. Janus kinase inhibitor GRCh38: Ensembl release 89: ENSG00000162434...

genes regulate cell growth and survival. Other genes (e.g. JAK3, STAT3, and STAT5B ) that are mutated in far lower percentages of cases also regulate these...

mutations in CIITA, RFXANK, RFX5, or RFXAP) CD25 deficiency CD27 deficiency STAT5b deficiency ITK deficiency SH2D1A deficiency (XLP1) MAGT1 deficiency DOCK2...

prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B". Molecular Endocrinology. 14 (9): 1338–50. doi:10.1210/mend.14.9.0513....

(January 2002). "Tumor necrosis factor alpha (TNF-alpha) activates Jak1/Stat3-Stat5B signaling through TNFR-1 in human B cells". Cell Growth & Differentiation...

PDGFRB, PI3K → Akt PLCG2, PTK2B, Ras SLAMF1, SOCS3, SOS1, STAT3, STAT5A, and STAT5B. CagA is a protein and virulence factor inserted by Helicobacter pylori...

the STAT protein family, composed of STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6. STAT proteins are key activators of gene transcription which bind...

formation. Mutations in JAK-STAT signaling pathway genes (i.e. JAK3 and STAT5B). This pathway regulates cell proliferation, death, and tumor formation...

and Reed-Sternberg tumor cells discovered recurrent mutations of STAT3, STAT5B, JAK1, JAK2 and PTPN1 that support the pivotal role of aberrant activation...

T cells that may have mutations or other genetic abnormalities in their STAT5B, JAK3, TP53, SETD2, BRAF, KRAS, GNA12, CREBBP, and/or Myc genes. Indolent...

P40763 15936 STAT4 HGNC:11365 Q14765 15937 STAT5A HGNC:11366 P42229 15938 STAT5B HGNC:11367 P51692 15939 STAT6 HGNC:11368 P42226 15940 STATH HGNC:11369 P02808...

subpopulations that have mutations: in other JAK-STAT pathway genes viz., STAT5B, JAK3, and SOCS1 (SOCS1 inhibits STAT signaling); tumor suppressor genes...

mice is dependent on signal transducer and activator of transcription 5b (STAT5b)". Molecular Endocrinology. 16 (6): 1394–1406. doi:10.1210/mend.16.6.0845...