Saquinavir, sold under the brand name Invirase among others, is an antiretroviral medication used together with other medications to treat or prevent HIV/AIDS...
16 KB (1,116 words) - 19:41, 20 December 2023
OX1001 (redirect from Saquinavir-NO)
OX1001 (saquinavir-NO) is an experimental drug being developed by OncoNOx currently undergoing clinical studies and investigations for the treatment of...
6 KB (558 words) - 00:06, 9 November 2023
Atazanavir Darunavir Fosamprenavir Indinavir Lopinavir Nelfinavir Ritonavir Saquinavir Tipranavir Hepatitis C virus NS3/4A protease inhibitors—class stem –previr: 26 ...
12 KB (838 words) - 10:11, 12 August 2024
capable of decreasing the absorption of some other drugs. As an example, saquinavir concentrations can decrease by half when given with loperamide. Loperamide...
47 KB (4,108 words) - 05:59, 15 August 2024
antagonists against the HIV protease were revealed in 1987. Phase I trials of saquinavir began in 1989 and it was the first HIV protease inhibitor to be approved...
33 KB (4,117 words) - 22:23, 23 August 2022
lead to a higher risk of bleeding. Garlic may interact with warfarin, saquinavir, antihypertensives, calcium channel blockers, the quinolone family of...
60 KB (6,729 words) - 07:49, 23 August 2024
(3TC) Lopinavir Maraviroc Nelfinavir Nevirapine Raltegravir Ritonavir Saquinavir Tenofovir Tipranavir Zalcitabine (ddC) Zidovudine (AZT) Androstanolone...
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ephedrine is used in bulk quantities as a chiral auxiliary group. In saquinavir synthesis, the half-acid is resolved as its salt with l-ephedrine. In...
48 KB (4,619 words) - 03:13, 28 July 2024
United States FDA's approval of Hoffman LaRoche's HIV protease inhibitor, saquinavir. Within 2 years of its approval (and that of ritonavir 4 months later)...
55 KB (5,124 words) - 05:32, 27 August 2024
Allium sativum has been found to decrease the plasma concentration of saquinavir, and may cause hypoglycemia when taken with chlorpropamide. Ginkgo biloba...
29 KB (2,971 words) - 18:45, 23 June 2024
itraconazole is contraindicated. Other CYP3A4 inhibitors including erythromycin, saquinavir, and verapamil should be used with caution. Other drugs that increase...
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Certain antiretroviral medications (e.g. indinavir, nevirapine, ritonavir, saquinavir, etc.) Progestogens Some anticonvulsants including: carbamazepine, ethosuximide...
64 KB (6,616 words) - 12:51, 17 August 2024
(Viagra) tadalafil (Cialis) vardenafil (Levitra) HIV protease inhibitors saquinavir (Invirase) ritonavir (Norvir) nelfinavir (Viracept) amprenavir (Agenerase)...
55 KB (5,720 words) - 16:53, 17 August 2024
December 6 – The United States Food and Drug Administration approves Saquinavir, the first protease inhibitor to treat HIV/AIDS. Within 2 years of its...
63 KB (5,137 words) - 21:47, 19 August 2024
cell. Also, azole may generate reactive oxygen species. Anti-viral agent Saquinavir HIV protease is needed to cleave Gag-Pol polyprotein into 3 individual...
41 KB (4,859 words) - 20:41, 22 July 2024
distortions of the sense of taste, and can be caused by medication, including saquinavir, zonisamide, and various kinds of chemotherapy, as well as occupational...
94 KB (10,370 words) - 10:14, 23 August 2024
Barry MG, Mulcahy F, Ryan M, Heavey J, Tjia JF, et al. (March 1997). "Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected...
42 KB (3,598 words) - 14:41, 6 August 2024
interactions. The first HIV protease inhibitor approved by the FDA was saquinavir, which was designed to target wild-type HIV-1 protease. However, this...
23 KB (1,806 words) - 22:59, 7 June 2024
the neuraminidase inhibitor oseltamivir and the HIV protease inhibitors saquinavir in the treatment of AIDS. The transition state of a structure can best...
12 KB (1,363 words) - 03:36, 27 October 2023
ketoconazole, lopinavir, nefazodone, nelfinavir, posaconazole, ritonavir, saquinavir, telaprevir, and telithromycin (concomitant use not recommended); the...
48 KB (4,078 words) - 11:27, 24 July 2024
A M2 proton channel antagonist Ritonavir HIV HIV-1 protease inhibitor Saquinavir HIV Simeprevir (Olysio) Hepatitis C Sofosbuvir Hepatitis C nucleoside...
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SULPHATE 444. SALICYL-AZO-SULPHAPYRIDINE 445. SALMON CALCITONIN 446. SAQUINAVIR 447. SATRANIDAZOLE 448. SECNIDAZOLE 449. SEPTOPAL BEADS & CHAINS 450....
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antagonists (except palonosetron), and some antiretrovirals (ritonavir, saquinavir, lopinavir). As an SSRI, escitalopram should not be given concurrently...
54 KB (5,094 words) - 23:53, 27 August 2024
astemizole, chlorphenamine; protease inhibitors: indinavir, ritonavir, saquinavir, nelfinavir; non-nucleoside reverse-transcriptase inhibitors (antiretroviral...
80 KB (7,794 words) - 21:26, 15 July 2024
(FPV) Indinavir (IDV)◊ Lopinavir (LPV) Nelfinavir (NFV)◊ Ritonavir (RTV)# Saquinavir (SQV)◊ 2nd generation Atazanavir (ATV)°# Darunavir (DRV)°# Tipranavir...
15 KB (1,230 words) - 02:38, 16 July 2024
from 1,2,3,4-tetrahydroisoquinoline). antiretroviral agents, such as saquinavir with an isoquinolyl functional group, (shown below). vasodilators, a well-known...
11 KB (1,095 words) - 05:24, 23 July 2024
as ketoconazole, itraconazole, clarithromycin, atazanavir, nefazodone, saquinavir, telithromycin, ritonavir, indinavir, nelfinavir, voriconazole) or inducers...
49 KB (4,210 words) - 04:31, 20 March 2024
saprisartan (INN) sapropterin dihydrochloride (USAN) sapropterin (INN) saquinavir (INN) saracatinib (USAN, INN) Sarafem sarafloxacin (INN) saralasin (INN)...
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darunavir, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, or saquinavir may experience colchicine toxicity. Grapefruit juice and statins can also...
55 KB (5,703 words) - 04:45, 26 August 2024
Omeprazole Orphenadrine Pantoprazole Piperine Quercetin Ranitidine Ritonavir Saquinavir Seproxetine ((S)-norfluoxetine/ Fluoxetine metabolite) Star fruit Telithromycin...
9 KB (78 words) - 09:09, 12 November 2023