• Thumbnail for Sonidegib
    Sonidegib (INN), sold under the brand name Odomzo, is a medication used to treat cancer. Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened...
    13 KB (1,058 words) - 01:41, 30 August 2024
  • Thumbnail for Basal-cell carcinoma
    These experimental procedures are not standard care. Vismodegib and sonidegib are drugs approved for specially treating BCC, but are expensive and cannot...
    55 KB (5,426 words) - 04:15, 2 November 2024
  • Administration (FDA) for cancer treatment. These include vismodegib and sonidegib, both inhibitors of Smoothened (SMO), which are being used for the treatment...
    27 KB (3,866 words) - 12:49, 22 August 2024
  • Thumbnail for Itraconazole
    treatment of cancer by inhibiting the hedgehog pathway in a similar way to sonidegib. Itraconazole has a broader spectrum of activity than fluconazole (but...
    26 KB (2,397 words) - 16:07, 20 May 2024
  • inhibitors are available for cancer treatment, such as vismodegib and sonidegib. These drugs are regarded as promising cancer therapies, especially for...
    59 KB (6,895 words) - 22:30, 25 April 2024
  • Thumbnail for Novartis
    Navoban (tropisetron) Chemotherapy-induced nausea and vomiting Odomzo (sonidegib) Locally advanced basal cell carcinoma Ritalin (methylphenidate) ADHD...
    144 KB (12,146 words) - 09:25, 31 October 2024
  • inhibitors Everolimus Ridaforolimus Temsirolimus hedgehog inhibitors Glasdegib Sonidegib Vismodegib CDK inhibitors Abemaciclib Dalpiciclib Palbociclib Ribociclib...
    12 KB (821 words) - 02:57, 12 October 2024
  • ribociclib -degib hedgehog signaling pathway inhibitors vismodegib, sonidegib -denib IDH1 and IDH2 inhibitors enasidenib, ivosidenib -lisib Phosphatidylinositol...
    26 KB (2,150 words) - 12:06, 11 September 2024
  • Panobinostat L01XH04 Belinostat L01XH05 Entinostat L01XJ01 Vismodegib L01XJ02 Sonidegib L01XJ03 Glasdegib L01XK01 Olaparib L01XK02 Niraparib L01XK03 Rucaparib...
    12 KB (877 words) - 15:36, 25 January 2024
  • Thumbnail for Vismodegib
    (14/2011): 10. Li Y, Song Q, Day BW (July 2019). "Phase I and phase II sonidegib and vismodegib clinical trials for the treatment of paediatric and adult...
    7 KB (483 words) - 19:42, 20 December 2023
  • Thumbnail for Targeted therapy
    trials Hedgehog pathway inhibitors (e.g. FDA approved vismodegib and sonidegib). Salinomycin has demonstrated potency in killing cancer stem cells in...
    20 KB (2,234 words) - 01:21, 22 July 2024
  • Thumbnail for Cyclopamine
    of cyclopamine have been approved by the FDA; vismodegib in 2012, and sonidegib in 2015. Vismodegib was the first Shh pathway drug approved for treating...
    16 KB (1,441 words) - 13:23, 1 June 2024
  • inhibitors Everolimus Ridaforolimus Temsirolimus hedgehog inhibitors Glasdegib Sonidegib Vismodegib CDK inhibitors Abemaciclib Dalpiciclib Palbociclib Ribociclib...
    12 KB (758 words) - 23:46, 14 March 2024
  • Thumbnail for Smoothened
    being investigated for the treatment of other types of cancer SANT-1 Sonidegib Patidegib Glasdegib Jervine Frizzled GRCh38: Ensembl release 89: ENSG00000128602...
    28 KB (3,490 words) - 16:24, 17 March 2024
  • treatment of cancer by inhibiting the hedgehog pathway in a similar way to Sonidegib. The majority of breast cancers are androgen receptor (AR) positive and...
    36 KB (4,350 words) - 18:30, 23 March 2024