• Thumbnail for Squalene
    Squalene is an organic compound. It is a triterpene with the formula C30H50. It is a colourless oil, although impure samples appear yellow. It was originally...
    19 KB (1,761 words) - 01:30, 14 June 2024
  • Thumbnail for Squalene monooxygenase
    Squalene monooxygenase (also called squalene epoxidase) is a eukaryotic enzyme that uses NADPH and diatomic oxygen to oxidize squalene to 2,3-oxidosqualene...
    10 KB (1,146 words) - 01:30, 22 December 2023
  • Thumbnail for Farnesyl-diphosphate farnesyltransferase
    Squalene synthase (SQS) or farnesyl-diphosphate:farnesyl-diphosphate farnesyl transferase is an enzyme localized to the membrane of the endoplasmic reticulum...
    26 KB (3,078 words) - 20:22, 4 September 2024
  • Thumbnail for Steroid
    Lanosterol and cycloartenol are derived from the cyclization of the triterpene squalene. Steroids are named after the steroid cholesterol which was first described...
    83 KB (8,473 words) - 20:57, 4 September 2024
  • the hydrogenated derivative of squalene, although commercial samples are derived from nature. In contrast to squalene, due to the complete saturation...
    7 KB (539 words) - 21:36, 10 September 2024
  • Thumbnail for Triterpene
    terpene units. Animals, plants and fungi all produce triterpenes, including squalene, the precursor to all steroids. Triterpenes exist in a great variety of...
    5 KB (509 words) - 14:51, 30 April 2023
  • Thumbnail for Hopanoids
    reacts with squalene in a reaction catalyzed by squalene monooxygenase during sterol biosynthesis. Furthermore, squalene binds to squalene-hopene cyclases...
    42 KB (4,594 words) - 15:54, 23 June 2024
  • Botryococcus squalene synthase (EC 1.3.1.96, SSL-2 (gene)) is an enzyme with systematic name squalene:NADP+ oxidoreductase. This enzyme catalyses the following...
    1 KB (117 words) - 13:23, 26 August 2023
  • Thumbnail for Squalene-hopene cyclase
    Squalene-hopene cyclase (SHC) (EC 5.4.99.17) or hopan-22-ol hydro-lyase is an enzyme in the terpene cyclase/mutase family. It catalyzes the interconversion...
    13 KB (1,430 words) - 15:52, 26 August 2023
  • Thumbnail for Terbinafine
    inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that catalyzes the conversion of squalene to lanosterol. In fungi, lanosterol is...
    20 KB (1,758 words) - 22:15, 3 August 2024
  • Squalene methyltransferase (EC 2.1.1.262, TMT-1, TMT-2) is an enzyme with systematic name S-adenosyl-L-methionine:squalene C-methyltransferase. This enzyme...
    2 KB (172 words) - 15:52, 26 August 2023
  • Squalene—hopanol cyclase (EC 4.2.1.129, squalene—hopene cyclase) is an enzyme with systematic name hopan-22-ol hydro-lyase. This enzyme catalyses the following...
    2 KB (170 words) - 15:52, 26 August 2023
  • The squalene/phytoene synthase family represents proteins that catalyze the head-to-head condensation of C15 and C20 prenyl units (i.e. farnesyl diphosphate...
    7 KB (785 words) - 17:39, 20 February 2023
  • systematic name squalene mutase (cyclizing, dammara-20,24-diene-forming). This enzyme catalyses the following chemical reaction: squalene ⇌ {\displaystyle...
    1 KB (90 words) - 13:44, 26 August 2023
  • led to a few clinical trials. Squalene is a naturally-occurring organic compound used in human and animal vaccines. Squalene is an oil, made up of carbon...
    38 KB (4,235 words) - 12:27, 3 September 2024
  • Thumbnail for 2009 swine flu pandemic vaccine
    suggested that squalene might be linked to autoimmune disorders. although others suggest squalene might protect people against cancer. Squalene-based adjuvants...
    96 KB (10,054 words) - 03:15, 4 September 2024
  • Tetrahymanol synthase (EC 4.2.1.123, squalene tetrahymanol cyclase) is an enzyme with systematic name squalene hydro-lyase (tetrahymanol forming). This...
    2 KB (149 words) - 16:00, 26 August 2023
  • E), dolichols, and squalene. Heme A has an isoprenoid tail, and lanosterol, the sterol precursor in animals, is derived from squalene and hence from isoprene...
    17 KB (1,703 words) - 16:36, 21 July 2024
  • Thumbnail for Kiehl's
    Sharkstewards (2019-12-05). "Squalene and Sharks". Shark Stewards. Retrieved 2024-07-10. Modems, The (2024-04-01). "The Squalene Found in Beauty Products...
    21 KB (1,914 words) - 21:54, 22 July 2024
  • Thumbnail for Siraitia grosvenorii
    revealed five enzyme families involved in the synthesis of mogroside V: squalene epoxidases, triterpenoid synthases, epoxide hydrolases, cytochrome P450s...
    16 KB (1,776 words) - 08:31, 7 September 2024
  • Thumbnail for Vernix caseosa
    ceramides, cholesterol, fatty acids, triglycerides, waxes and sterol esters, squalene, and phospholipids; multiple detailed analyses of the polar components...
    12 KB (1,335 words) - 02:38, 17 June 2024
  • Thumbnail for Butenafine
    contents to leak out. Furthermore, inhibition of squalene epoxidase leads to a toxic buildup of squalene. This double action of butenafine (increased membrane...
    6 KB (485 words) - 16:52, 15 July 2024
  • Thumbnail for Terpene
    building blocks. Steroids, for example, are derivatives of the triterpene squalene. Terpenes and terpenoids are also the primary constituents of the essential...
    32 KB (3,485 words) - 02:54, 22 August 2024
  • cycloartenol, as well as saponins. It is formed when squalene is oxidized by the enzyme squalene monooxygenase. 2,3-Oxidosqualene is the substrate of...
    3 KB (97 words) - 06:26, 12 July 2024
  • Thumbnail for Sebaceous gland
    esters (≈26%), squalene (≈12%), and free fatty acids (≈16%). The composition of sebum varies across species. Wax esters and squalene are unique to sebum...
    29 KB (3,377 words) - 15:16, 1 September 2024
  • Thumbnail for Antifungal
    Propiconazole Ravuconazole Terconazole Voriconazole Abafungin Allylamines inhibit squalene epoxidase, another enzyme required for ergosterol synthesis. Examples include...
    28 KB (2,588 words) - 11:09, 26 August 2024
  • Thumbnail for Amaranth
    pepperpot soup. Making up about 5% of the total fatty acids of amaranth, squalene is extracted as a vegetable-based alternative to the more expensive shark...
    53 KB (5,617 words) - 03:47, 28 August 2024
  • Thumbnail for Lanosterol
    isopentenyl pyrophosphate (IPP), dimethylallyl pyrophosphate (DMAPP), geranyl pyrophosphate (GPP), and squalene shown. Some intermediates are omitted....
    6 KB (305 words) - 03:31, 19 August 2024
  • Thumbnail for Cholesterol
    condense to form squalene by the action of squalene synthase in the endoplasmic reticulum. Oxidosqualene cyclase then cyclizes squalene to form lanosterol...
    80 KB (8,653 words) - 20:33, 10 September 2024
  • Thumbnail for Metabolism
    donors is sterol biosynthesis. Here, the isoprene units are joined to make squalene and then folded up and formed into a set of rings to make lanosterol. Lanosterol...
    113 KB (12,400 words) - 00:04, 12 September 2024