• In retrosynthetic analysis, a synthon is a hypothetical unit within a target molecule that represents a potential starting reagent in the retroactive...
    7 KB (810 words) - 18:42, 3 February 2024
  • Thumbnail for Synthon (company)
    Synthon is a Dutch multinational that produces generic human drugs. The company was founded in 1991 by Jacques Lemmens and Marijn Oosterbaan, two organic...
    3 KB (232 words) - 14:03, 23 April 2024
  • single target. Synthon A fragment of a compound that assists in the formation of a synthesis, derived from that target molecule. A synthon and the corresponding...
    7 KB (749 words) - 02:51, 11 February 2024
  • Thumbnail for C1 chemistry
    C1 chemistry (redirect from C1 synthon)
    C1 chemistry is the chemistry of one-carbon molecules. Although many compounds and ions contain only one carbon, stable and abundant C-1 feedstocks are...
    4 KB (400 words) - 23:37, 26 April 2023
  • distillation. Overall, decarboxylation depends upon stability of the carbanion synthon R− , although the anion may not be a true chemical intermediate. Typically...
    12 KB (1,289 words) - 10:16, 20 May 2024
  • Thumbnail for Phenylmagnesium bromide
    reagent. It is often used as a synthetic equivalent for the phenyl "Ph−" synthon. Phenylmagnesium bromide is commercially available as solutions of diethyl...
    5 KB (337 words) - 16:03, 6 January 2022
  • Thumbnail for 4,4'-Dinitro-3,3'-diazenofuroxan
    IV, Pivina TS (1999). 4-Amino-3-azidocarbonyl Furoxan as an Universal Synthon for the Synthesis of Energetic Compounds of the Furoxan Series. 30th International...
    2 KB (127 words) - 07:48, 25 August 2024
  • Thumbnail for Cyanide
    organic cyanides are called nitriles. In organic synthesis, cyanide is a C-1 synthon; i.e., it can be used to lengthen a carbon chain by one, while retaining...
    35 KB (3,927 words) - 12:22, 7 September 2024
  • Thumbnail for Olanzapine
    Health, Olanzapine Sanovel, Olanzapine Stada, Olanzapine Sun, Olanzapine Synthon, Olanzapine Teva, Olanzapine Torrent, Olanzapine Zentiva, Olanzapine Zentiva...
    92 KB (8,663 words) - 04:51, 8 September 2024
  • Thumbnail for Haloalkane
    hydrocarbons, as well as the halogenated product. Haloalkanes behave as the R+ synthon, and readily react with nucleophiles. Hydrolysis, a reaction in which water...
    20 KB (2,413 words) - 06:14, 8 September 2024
  • Thumbnail for Benzoyl chloride
    derivatives. With carbanions, it serves again as a source of the benzoyl cation synthon, C6H5CO+. Benzoyl peroxide, a common reagent in polymer chemistry, is produced...
    6 KB (444 words) - 16:19, 8 June 2024
  • SGCOxCompounds, SGCStoCompounds SMID Specs Structural Genomics Consortium SureChem Synthon-Lab Thomson Pharma Total TOSLab Building-Blocks UM-BBD UPCMLD UsefulChem...
    13 KB (1,196 words) - 18:07, 30 January 2024
  • Thumbnail for Biolex
    by Biolex. In May 2012 Biolex announced that it sold the LEX System to Synthon, a Netherlands-based specialty pharmaceutical company. The sale included...
    4 KB (382 words) - 22:50, 28 April 2022
  • functional groups have been synthesized, serving as CO2 and α-diketone synthons. Finally, Stephen G. Davies of Oxford has designed a chiral auxiliary that...
    12 KB (1,293 words) - 13:36, 26 August 2024
  • Thumbnail for 7-ACA
    7-ACA (7-aminocephalosporanic acid) is the core chemical structure (a synthon) for the synthesis of cephalosporin antibiotics and intermediates. It can...
    4 KB (168 words) - 15:18, 30 August 2024
  • Thumbnail for Malonic acid
    transformations. The esters of malonic acid are also used as a −CH2COOH synthon in the malonic ester synthesis. Malonic acid is a key component in the...
    20 KB (1,985 words) - 02:27, 6 September 2024
  • Thumbnail for Tamsulosin
    Omnic by Astellas Pharma Europe. The largest manufacturer of tamsulosin is Synthon BV (the Netherlands).[citation needed] Tamsulosin hydrochloride is marketed...
    17 KB (1,438 words) - 00:14, 1 September 2024
  • the malonic ester can be thought of being equivalent to the −CH2COOH synthon. The esters chosen are usually the same as the base used, i.e. ethyl esters...
    4 KB (315 words) - 22:53, 28 March 2024
  • Thumbnail for Amino acid
    (September 2001). "The Use of Carbon Monoxide and Imines as Peptide Derivative Synthons: A Facile Palladium-Catalyzed Synthesis of α-Amino Acid Derived Imidazolines"...
    98 KB (10,141 words) - 04:18, 2 September 2024
  • Thumbnail for Iodobenzene
    like the bromide analog, is a synthetic equivalent for the phenyl anion synthon. Iodobenzene reacts with chlorine to give the complex, iodobenzene dichloride...
    4 KB (304 words) - 23:09, 9 February 2024
  • Thumbnail for Dimethyl sulfide
    Dictyopterene A: Optically Active Tributylstannylcyclopropane as a Chiral Synthon". Bulletin of the Chemical Society of Japan. 73 (2): 409–416. doi:10.1246/bcsj...
    21 KB (2,079 words) - 03:36, 12 September 2024
  • Thumbnail for Phosgene
    electrophilic character of this reagent and its use in introducing the equivalent synthon "CO2+": R−NH2 + COCl2 → R−N=C=O + 2 HCl, where R = alkyl, aryl Such reactions...
    30 KB (3,150 words) - 01:09, 25 August 2024
  • Thumbnail for Hydroxide
    Slawin, Alexandra M. Z.; Nolan, Steven P. (2010). "A Versatile Cuprous Synthon: [Cu(IPr)(OH)] (IPr = 1,3 bis(diisopropylphenyl)imidazol-2-ylidene)". Organometallics...
    41 KB (4,891 words) - 13:03, 26 August 2024
  • (formerly Sepracor) (1984– ) Sutro (2003– ) Swedish Orphan Biovitrum (2001– ) Synthon (1991– ) Taisho (1912– ) Takeda (1781– ) Taro (1950– ) Tasly (1994– ) Teijin...
    34 KB (2,168 words) - 15:30, 26 August 2024
  • synthesis, EtBr is the synthetic equivalent of the ethyl carbocation (Et+) synthon. In reality, such a cation is not actually formed. For example, carboxylates...
    6 KB (358 words) - 13:08, 7 September 2024
  • Thumbnail for Ethylmagnesium bromide
    compounds. Apart from acting as the synthetic equivalent of an ethyl anion synthon for nucleophilic addition, ethylmagnesium bromide may be used as a strong...
    2 KB (152 words) - 23:10, 30 July 2024
  • Thumbnail for Nijmegen
    in Nijmegen. Other notable companies headquartered in Nijmegen include Synthon, a Dutch multinational pharmaceutical company and Vaxxinova, an EW group...
    44 KB (4,234 words) - 18:35, 15 September 2024
  • Thumbnail for Crystal engineering
    These may be understood with key concepts such as the supramolecular synthon and the secondary building unit. The term 'crystal engineering' was first...
    26 KB (2,702 words) - 02:57, 9 November 2023
  • (retro-aldol cleavage) from serine, transferring the resulting formalddehyde synthon to 5,6,7,8-tetrahydrofolate. However, that reaction is reversible, and...
    24 KB (2,392 words) - 23:10, 9 September 2024
  • Thumbnail for Elias James Corey
    Massachusetts Institute of Technology (BS, PhD) Known for Retrosynthetic analysis Synthon Corey–Bakshi–Shibata catalyst Corey–Chaykovsky reaction Corey–Fuchs reaction...
    55 KB (5,643 words) - 08:54, 13 September 2024