Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted...

growth factor beta receptor I (activin A receptor type II-like kinase, 53kDa) is a membrane-bound TGF beta receptor protein of the TGF-beta receptor family...

Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different...

263 (32): 16984–91. doi:10.1016/S0021-9258(18)37487-8. PMID 2903157. TGF-beta+Receptors at the U.S. National Library of Medicine Medical Subject Headings...

Nodal and TGFβs. Signaling begins with the binding of a TGF beta superfamily ligand to a TGF beta type II receptor. The type II receptor is a serine/threonine...

Transforming growth factor, beta receptor II (70/80kDa) is a TGF beta receptor. TGFBR2 is its human gene. It is a tumor suppressor gene. This gene encodes...

The transforming growth factor beta (TGFβ) receptors are a family of serine/threonine kinase receptors involved in TGF beta signaling pathway. These receptors...

factor beta (TGF-β) superfamily is a large group of structurally related cell regulatory proteins that was named after its first member, TGF-β1, originally...

Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during...

Transforming growth factor beta (TGF-β) is a potent cell regulatory polypeptide homodimer of 25kD. It is a multifunctional signaling molecule with more...

The latent TGF-beta binding proteins (LTBP) are a family of carrier proteins. LTBP is a family of secreted multidomain proteins that were originally identified...

growth factor, beta 3 has been shown to interact with TGF beta receptor 2. After successful phase I/II trials, human recombinant TGF-β3 (Avotermin, planned...

"Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1". The Journal of Cell Biology. 165 (5): 723–34...

DB, Sheppard D (February 1999). "The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and...

Metelimumab (CAT-192) is a human IgG4 monoclonal antibody that neutralizes TGF beta 1 which had been chosen for further development for the treatment of diffuse...

wound healing. It is dormant in most mammals. Also, the proteins MG53 and TGF beta 1 play important roles in wound healing. In response to an incision or wound...

beta-binding protein 1 is a protein that in humans is encoded by the LTBP1 gene. The protein encoded by this gene belongs to the family of latent TGF-beta...

The increase in TGF-beta 1 expression in a pressure-overloaded heart correlates with the degree of fibrosis, suggesting TGF-beta 1 involvement in the...

to and inhibits all isoforms of the protein transforming growth factor beta (TGF-β). Fresolimumab was discovered by Cambridge Antibody Technology (CAT)...

TGF-beta superfamily of ligands via its core protein, and bFGF via its heparan sulfate chains. TGFBR3 is the most widely expressed type of TGF-beta receptor...

addition, stellate cells secrete TGF beta 1, which leads to a fibrotic response and proliferation of connective tissue. TGF-β1 have been implicated in the...

[citation needed] Other inflammatory mediators that can increase CRP are TGF beta 1, and tumor necrosis factor alpha. In acute inflammation, CRP can increase...

eight-cysteine domains homologous with latent TGF-beta binding protein, and a proline-rich region. The FBN-1 gene is involved in a variety of embryonic developmental...

transforming growth factor-beta (TGF-beta). Decorin has been shown to either enhance or inhibit the activity of TGF-beta 1. The primary function of decorin...

Catenin beta-1, also known as β-catenin (beta-catenin), is a protein that in humans is encoded by the CTNNB1 gene. β-Catenin is a dual function protein...

Forbius and its TGF-beta 1 & TGF-beta 3 inhibitors. In October, BMS announced it would acquire cardiology company MyoKardia for $13.1 billion ($225 per...

his Protective Cytokine Hypothesis explaining the role of the cytokine TGF-beta 1 in the cardiovascular system, Grainger was appointed principal investigator...

main signal transducers for receptors of the transforming growth factor beta (TGF-B) superfamily, which are critically important for regulating cell development...

factor-beta (TGF-β1) are also thought to be involved in the pathogenesis of pre-eclampsia. They belong to the transforming growth factor beta family....

type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. It is also commonly referred to as CD105, END, FLJ41744...