an ion channel protein that in humans is encoded by the TRPV4 gene. The TRPV4 gene encodes TRPV4, initially named "vanilloid-receptor related osmotically...

channel, transient receptor potential cation channel, subfamily V, member 4 (TRPV4). The mutation is a V342F substitution (c.1024G>T) in the fifth ankyrin...

scabies mite. It probably acts as a general antipruritic by inhibition of TRPV4, a sensory ion channel that is expressed in the skin and primary sensory...

channels (CatSper1, TASK, RyR1, RyR2, RyR3, TRPM6, TRPM8, TRPV1, TRPV2, TRPV3, TRPV4, TRPV5, TRPV6, TRPA1, mCa1, mCa2, CALHM1) TRPP3, a plant ion channel, Ca2+-ATPase...

publications related to TRPV4. His TRPV4-related work has been referenced 12597 times, accounting for 14.2% of the entire TRPV4 field's citations. In addition...

Channels shown: TRPA1, TRPM8, TRPV4, TRPV3, TRPV1, TRPM3, ANO1, TRPV2...

a mutation of the TRPV4 gene found on the 12q23-12q24.1. The mutation causes an affected individual to have lower levels of TRPV4 expression. This deficiency...

TRPV1, TRPM3 and to some extent TRPM8. LPS is recognized by TRPV4 on epithelial cells. TRPV4 activation by LPS was necessary and sufficient to induce nitric...

Additionally, CBC is an agonist of TRPA1, and less potently TRPV3 and TRPV4. CBC has two stereoisomers. "Cannabichromene". PubChem. National Center...

as a potent and selective blocker of the TRPV4 ion channel. It has been used to investigate the role of TRPV4 channels in the function of heart valves...

a potent and selective antagonist for the TRPV4 receptor. It has been used to investigate the role of TRPV4 receptors in a number of areas, such as regulation...

TRPV1, TRPM3 and to some extent TRPM8. LPS is recognized by TRPV4 on epithelial cells. TRPV4 activation by LPS was necessary and sufficient to induce nitric...

(EC50 = 1,300 nM), TRPV2 (EC50 = 1,720 nM), TRPV3 (EC50 = 1,000 nM), and TRPV4 (EC50 = 5,100 nM) (efficacy 18–100% at these targets) and a more potent...

canonical 6 (TRPC6) channels, and transient receptor potential vanilloid 4 (TRPV4) channels. Recently it was proposed that hypoxia is sensed at the alveolar/capillary...

acts as a potent and selective agonist for the TRPV4 receptor. It has been used to study the role of TRPV4 receptors in the function of smooth muscle tissue...

multiple types HSPB8, HSPB1, HSPB3, GARS, REEP1, IGHMBP2, SLC5A7, DCTN1, TRPV4, SIGMAR1 Distal muscular dystrophy Dysferlin, TIA1, GNE (gene), MYH7, Titin...

phytocannabinoid at TRPA1 Very low efficacy at TRPV1 and TRPV4, but may reduce expression of TRPV4 in the presence of inflammation High affinity for CB1...

significance to TRPV1, TRPV2, and TRPV3's role as thermoreceptors, and TRPV4's role as mechanoreceptors; reduction of chronic pain may be possible by...

hypertonicity sensing operated via a mechanical mechanism of TRPV1 but not TRPV4. Despite a significant amount of data, the anatomy of the VOLT is not yet...

their associated cardiac cilia by way of the mechanosensitive ion channel TRPV4, subsequently facilitating the Notch signaling pathway via KLF2 and activating...

which means it is apparent at birth. It is caused by a mutation in the TRPV4 gene, located on chromosome 12 in humans. The disease is inherited in an...

; Shahidullah, Mohammad (31 January 2022). "Ion Transport Regulation by TRPV4 and TRPV1 in Lens and Ciliary Epithelium". Frontiers in Physiology. 12:...

laminopathy CMT2B2 605589 MED25 19q13.33 Autosomal dominant CMT2C 606071 TRPV4 12q24.11 Autosomal dominant May cause vocal cord, diaphragm, and distal...

protein–coupled receptors to inhibit pain receptors (i.e. TRPV1, TRPV3, TRPV4, TRPA1, TNFR, NMDAR, and/or mGluR) on neurons in the peripheral nervous...

Miyagawa S, Kohno S, Saito S, Lowers RH, Ogino Y, et al. (December 2015). "TRPV4 associates environmental temperature and sex determination in the American...

muscular atrophy Distal hereditary motor neuronopathy type 8 (DHMN8) 600175 TRPV4 12q24.11 Autosomal dominant Affects primarily distal muscles of lower limbs...

is not the only TRP channel expressed in immune cells. TRPA1, TRPM8 and TRPV4 are the most relevant TRP channels that are also studied in immune cells...

Q8NER1 17480 TRPV2 HGNC:18082 Q9Y5S1 17481 TRPV3 HGNC:18084 Q8NET8 17482 TRPV4 HGNC:18083 Q9HBA0 17483 TRPV5 HGNC:3145 Q9NQA5 17484 TRPV6 HGNC:14006 Q9H1D0...

surface expressed ion channel, transient receptor potential vanilloid 4 (TRPV4) as a cause of SMA and CMT2 and is currently developing treatment for this...

TRPM1; TRPM2; TRPM3; TRPM4; TRPM5; TRPM6; TRPM7; TRPM8 TRPV1; TRPV2; TRPV3; TRPV4; TRPV5; TRPV6 MCOLN1; MCOLN2; MCOLN3; TRPA1 PKD1L3; CACNA1A; CACNA1B; CACNA1C;...