Thalidomide, sold under the brand names Contergan and Thalomid among others, is an oral medication used to treat a number of cancers (e.g., multiple myeloma)...

In the late 1950s and early 1960s, the use of thalidomide in 46 countries was prescribed to women who were pregnant or who subsequently became pregnant...

cause of phocomelia is the mother being prescribed the use of the drug thalidomide during pregnancy; however, the causes of most cases are to be determined...

Chemical agents Prescription and recreational drugs (e.g., alcohol, thalidomide) Environmental toxins and contaminants (e.g., heavy metals such as mercury...

immune responses) containing an imide group. The IMiD class includes thalidomide and its analogues (lenalidomide, pomalidomide, mezigdomide and iberdomide)...

considered a side effect. For information regarding birth defects, see thalidomide. Somnolence (drowsiness; ~40%) Edema (~60%) Hypotension (low blood pressure)...

the U.S. Food and Drug Administration (FDA), she refused to authorize thalidomide for market because she had concerns about the lack of evidence regarding...

1962) is an English thalidomide survivor and activist. She is a past chair of the National Advisory Committee of the Thalidomide Trust, the organisation...

the teratogenic drug thalidomide, marketed as the sleeping pill Contergan and promoted as a morning sickness preventive. Thalidomide caused severe birth...

Wonder Drug: The Secret History of Thalidomide in America and Its Hidden Victims is a nonfiction book authored by Jennifer Vanderbes and published by...

English rock musician, actor, writer and performance artist. He has thalidomide-induced phocomelia. Between 1980 and 1995 Fraser was a drummer with several...

Canadian paralympic gold medallist swimmer, and thalidomide survivor. She was president of the Thalidomide Victims Association of Canada in 2019. Lake was...

example of the importance of stereochemistry relates to the thalidomide disaster. Thalidomide is a pharmaceutical drug, first prepared in 1957 in Germany...

a British thalidomide survivor, painter, lace maker, and carriage driver with the RDA. Mercer was a representative of the global thalidomide community...

Australian obstetrician. He published a letter on the teratogenicity of thalidomide following the findings of a midwife named Pat Sparrow, which resulted...

Thalidomide!! A Musical is a British musical written and composed by Mat Fraser, who was born with phocomelia as a result of the drug thalidomide being...

adjusted in people with kidney problems. Lenalidomide is closely related to thalidomide, which is known to cause severe birth defects, so its use during pregnancy...

thalidomide was first made available on 1 October 1957, and it became the second best-selling medication in Germany after Bayer Aspirin. Thalidomide was...

following the thalidomide disaster the development and licensing of drugs changed dramatically. First synthesized in 1953, thalidomide was widely prescribed...

wildly in their pharmacokinetic, pharmacodynamic profile. The tragedy of thalidomide illustrates the potential for extreme consequences resulting from the...

the other enantiomer is harmful, like salbutamol and thalidomide. The (R) enantiomer of thalidomide is effective against morning sickness, while the (S)...

deficiency), drugs (e.g. anticancer drugs, tetracyclines, many hormones, thalidomide), and environmental chemicals (e.g. mercury, lead, dioxins, PBDEs, HBCD...

gain support for the survivors of thalidomide. Her efforts resulted in life-time compensation for Canadian "thalidomiders", as well as a special fund for...

antagonist. Racemization of pharmaceutical drugs can occur in vivo. Thalidomide as the (R) enantiomer is effective against morning sickness, while the...

activity of thalidomide in the chick and zebrafish was cast into doubt due to a 2013 report that pomalidomide (a more potent thalidomide analogue) does...

rather than by sound. Taussig is also known for her work in banning thalidomide and was widely recognized as a highly skilled physician. She was the...

Posit (fallacious) Medical testing on animals is useless. The drug thalidomide passed animal tests but resulted in horrific birth defects when used...

"Mikey" Argy, who was born with shortened arms due to a birth defect from thalidomide, a sleeping pill developed in Germany. Michaelina was awarded an MBE...

compound of pomalidomide, thalidomide, was originally discovered to inhibit angiogenesis in 1994. Based upon this discovery, thalidomide was taken into clinical...

1939) is a London art dealer and Thalidomide parent activist. He is the father of a daughter, Louise, disabled by thalidomide. Mason was educated at Highgate...