• Toxicodynamics, termed pharmacodynamics in pharmacology, describes the dynamic interactions of a toxicant with a biological target and its biological effects...
    25 KB (3,269 words) - 20:18, 15 January 2024
  • Thumbnail for Pharmacodynamics
    Pharmacokinetics and pharmacodynamics are termed toxicokinetics and toxicodynamics in the field of ecotoxicology. Here, the focus is on toxic effects on...
    19 KB (2,225 words) - 21:08, 29 May 2024
  • Thumbnail for Abrin
    Abrin is an extremely toxic toxalbumin found in the seeds of the rosary pea (or jequirity pea), Abrus precatorius. It has a median lethal dose of 0.7 micrograms...
    19 KB (2,291 words) - 00:11, 13 June 2024
  • A latrotoxin is a high-molecular mass neurotoxin found in the venom of spiders of the genus Latrodectus (widow spiders) as well as at least one species...
    17 KB (2,274 words) - 00:42, 29 June 2024
  • In toxicodynamics and pharmacodynamics, Loewe additivity (or dose additivity) is one of several common reference models used for measuring the effects...
    4 KB (571 words) - 11:04, 31 October 2023
  • Thumbnail for Bifenthrin
    Bifenthrin is a pyrethroid insecticide. It is widely used against ant infestations. Bifenthrin is poorly soluble in water and often remains in soil. Its...
    18 KB (1,940 words) - 21:03, 23 August 2024
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    through the feces, and very small amounts in hair, nails, and sweat. Toxicodynamics describes how the toxin affects the body, including the mechanisms causing...
    198 KB (21,311 words) - 19:59, 26 September 2024
  • Cadmium is a naturally occurring toxic metal with common exposure in industrial workplaces, plant soils, and from smoking. Due to its low permissible exposure...
    22 KB (2,624 words) - 01:01, 2 October 2024
  • toxic effects, toxicokinetics can be combined with toxicodynamics. Such toxicokinetic-toxicodynamic (TKTD) models are used in ecotoxicology (see ecotoxmodels...
    4 KB (468 words) - 21:15, 20 July 2022
  • Thumbnail for Fumonisin B1
    Fumonisin B1 is the most prevalent member of a family of toxins, known as fumonisins, produced by multiple species of Fusarium molds, such as Fusarium...
    27 KB (3,202 words) - 14:45, 18 September 2024
  • Bolon, Brad (eds.), "Chapter 4 - Principles of Pharmacodynamics and Toxicodynamics", Fundamentals of Toxicologic Pathology (Third Edition), Academic Press...
    6 KB (625 words) - 00:59, 6 June 2024
  • Benoxaprofen, also known as Benoxaphen, is a chemical compound with the formula C16H12ClNO3. It is a non-steroidal anti-inflammatory drug (NSAID) of the...
    24 KB (2,663 words) - 17:28, 7 September 2024
  • Thumbnail for Hexachlorocyclopentadiene
    Hexachlorocyclopentadiene (HCCPD), also known as C-56, Graphlox, and HRS 1655, is an organochlorine compound with the formula C5Cl6. It is a precursor...
    22 KB (2,929 words) - 15:53, 8 May 2024
  • Thumbnail for Liver disease
    particulate matter and carbon black are very diverse and each has different toxicodynamics, detailed mechanisms of translocation are not clear. Water-soluble fractions...
    29 KB (2,820 words) - 11:00, 12 September 2024
  • Protoxin-I, also known as ProTx-I, or Beta/omega-theraphotoxin-Tp1a, is a 35-amino-acid peptide neurotoxin extracted from the venom of the tarantula Thrixopelma...
    16 KB (1,797 words) - 03:30, 2 May 2024
  • Thumbnail for Apamin
    Apamin is an 18 amino acid globular peptide neurotoxin found in apitoxin (bee venom). Dry bee venom consists of 2–3% of apamin. Apamin selectively blocks...
    19 KB (1,992 words) - 22:36, 21 August 2024
  • Thumbnail for Leptophos
    Leptophos (O-(4-bromo-2,5-dichlorophenyl) O-methyl phenylphosphonothioate) belongs to the organophosphates and at room temperature it is a stable white...
    14 KB (1,183 words) - 08:48, 23 December 2023
  • Thumbnail for Batroxobin
    Batroxobin, also known as reptilase, is a snake venom enzyme with Venombin A activity produced by Bothrops atrox and Bothrops moojeni, venomous species...
    15 KB (2,037 words) - 21:44, 18 October 2023
  • Thumbnail for Arenobufagin
    Arenobufagin is a cardiotoxic bufanolide steroid secreted by the Argentine toad Bufo arenarum. It has effects similar to digitalis, blocking the Na+/K+...
    13 KB (1,536 words) - 00:10, 8 August 2024
  • Thumbnail for Enzyme inhibitor
    2001). "The toxicology of microcystin-LR: occurrence, toxicokinetics, toxicodynamics, diagnosis and treatment". Veterinary and Human Toxicology. 43 (5):...
    104 KB (11,579 words) - 19:29, 18 September 2024
  • Thumbnail for Pharmacokinetics
    2011). "General unified threshold model of survival--a toxicokinetic-toxicodynamic framework for ecotoxicology". Environmental Science & Technology. 45...
    46 KB (4,510 words) - 13:42, 23 September 2024
  • Thumbnail for Vancomycin
    et al. (2020). "Vancomycin-Induced Kidney Injury: Animal Models of Toxicodynamics, Mechanisms of Injury, Human Translation, and Potential Strategies for...
    83 KB (8,190 words) - 02:52, 25 October 2024
  • Thumbnail for N-Methylphenethylamine
    amine-associated receptor 1 (hTAAR1). It has comparable pharmacodynamic and toxicodynamic properties to that of phenethylamine, amphetamine, and other methylphenethylamines...
    10 KB (1,125 words) - 02:12, 22 April 2024
  • Thumbnail for Dose–response relationship
    mathematical models in ecotoxicology, with emphasis on toxicokinetic-toxicodynamic models CDD Vault, Example of Dose-Response Curve fitting software...
    17 KB (1,788 words) - 21:35, 5 September 2024
  • (355 nm) or N2 (337 nm) laser for ionization. Pharmacodynamics and toxicodynamics in tissue have been studied by MALDI imaging. Desorption electrospray...
    28 KB (3,322 words) - 17:12, 26 May 2024
  • Thumbnail for Diazinon
    Retrieved 31 May 2019. Kretschmann, Andreas; et al. (2011). "Mechanistic Toxicodynamic Model for Receptor-Mediated Toxicity of Diazoxon, the Active Metabolite...
    20 KB (2,154 words) - 19:03, 14 May 2024
  • Thumbnail for Drugs and sexual consent
    Morse, Bridget L.; Morris, Marilyn E. (2013-06-28). "Toxicokinetics/Toxicodynamics ofγ-Hydroxybutyrate-Ethanol Intoxication: Evaluation of Potential Treatment...
    32 KB (3,618 words) - 16:27, 24 October 2024
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    Ehsan; Arjmand, Abdollah; Pourahmad, Jalal (December 2019). "A Review on Toxicodynamics of Depleted Uranium". Iranian Journal of Pharmaceutical Research. 18...
    31 KB (3,754 words) - 06:56, 20 September 2024
  • humans and animals (as appropriate), the substance's toxicokinetics and toxicodynamics (including carry-over of the toxic substance from feed to edible animal...
    7 KB (829 words) - 06:20, 20 February 2024
  • 2003, The Bayesian population approach to physiological toxicokinetic-toxicodynamic models – An example using the MCSim software, Toxicology Letters 138:143-150...
    7 KB (989 words) - 04:39, 1 January 2024