• Thumbnail for Tyrosine-protein kinase Yes
    Tyrosine-protein kinase Yes is a non-receptor tyrosine kinase that in humans is encoded by the YES1 gene. This gene is the cellular homolog of the Yamaguchi...
    8 KB (1,028 words) - 12:23, 11 May 2024
  • Thumbnail for Tyrosine-protein kinase CSK
    Tyrosine-protein kinase CSK also known as C-terminal Src kinase is an enzyme that, in humans, is encoded by the CSK gene. This enzyme phosphorylates tyrosine...
    8 KB (977 words) - 00:09, 6 October 2021
  • Thumbnail for Proto-oncogene tyrosine-protein kinase Src
    Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc", as it is short for sarcoma)...
    21 KB (2,648 words) - 12:12, 26 July 2024
  • Thumbnail for Janus kinase 2
    Janus kinase 2 (commonly called JAK2) is a non-receptor tyrosine kinase. It is a member of the Janus kinase family and has been implicated in signaling...
    28 KB (3,166 words) - 14:44, 22 June 2024
  • Src kinase family is a family of non-receptor tyrosine kinases that includes nine members: Src, Yes, Fyn, and Fgr, forming the SrcA subfamily, Lck, Hck...
    10 KB (1,215 words) - 03:15, 19 April 2024
  • Thumbnail for LYN
    LYN (redirect from Lyn (Src family kinase))
    Tyrosine-protein kinase Lyn is a protein that in humans is encoded by the LYN gene. Lyn is a member of the Src family of protein tyrosine kinases, which...
    32 KB (3,807 words) - 13:31, 4 April 2024
  • Thumbnail for FYN
    FYN (category Tyrosine kinases)
    Proto-oncogene tyrosine-protein kinase Fyn (p59-FYN, Slk, Syn, MGC45350, Gene ID 2534) is an enzyme that in humans is encoded by the FYN gene. Fyn is...
    40 KB (4,778 words) - 18:07, 30 March 2024
  • response to extracellular signals. Key proteins involved are PI3K (phosphatidylinositol 3-kinase) and Akt (protein kinase B). Initial stimulation by one of...
    37 KB (4,145 words) - 08:04, 3 July 2024
  • Thumbnail for Stress granule
    energy sensor" AMP-activated protein kinase (AMPK), the O-GlcNAc transferase enzyme (OGT), and the pro-apoptotic kinase ROCK1. RNA phase transitions driven...
    183 KB (12,458 words) - 20:40, 1 July 2024
  • Thumbnail for Cyclin-dependent kinase 2
    Cyclin-dependent kinase 2, also known as cell division protein kinase 2, or Cdk2, is an enzyme that in humans is encoded by the CDK2 gene. The protein encoded...
    35 KB (4,314 words) - 00:26, 6 July 2024
  • Thumbnail for YAP1
    YAP1 (redirect from YAP (protein))
    virtue of its ability to associate with the SH3 domain of Yes and Src protein tyrosine kinases. YAP1 is a potent oncogene, which is amplified in various...
    30 KB (3,445 words) - 20:49, 6 July 2024
  • Thumbnail for Paracrine signaling
    of cancer. The Kit proto-oncogene encodes a tyrosine kinase receptor whose ligand is a paracrine protein called stem cell factor (SCF), which is important...
    46 KB (4,967 words) - 21:12, 7 July 2024
  • Thumbnail for STK11
    Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a protein kinase that in humans is encoded...
    25 KB (2,818 words) - 22:50, 12 May 2024
  • Thumbnail for AKT2
    AKT2 (category Protein kinases)
    AKT2, also known as RAC-beta serine/threonine-protein kinase, is an enzyme that in humans is encoded by the AKT2 gene. It influences metabolite storage...
    13 KB (1,578 words) - 20:13, 7 July 2024
  • involving mitogen-activated protein kinase (MAPK), leading to mitosis. Mitogens act primarily by influencing a set of proteins which are involved in the...
    13 KB (1,750 words) - 15:41, 27 July 2024
  • transmembrane receptor types: G protein coupled receptors (GPCRs), tyrosine kinase receptors (RTKs), serine/threonine kinase receptors (RSTKs), and ligand-gated...
    99 KB (11,432 words) - 18:01, 29 April 2024
  • Thumbnail for AKT1
    AKT1 (category Protein kinases)
    serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. This enzyme belongs to the AKT subfamily of serine/threonine kinases that...
    24 KB (2,879 words) - 13:02, 7 July 2024
  • Thumbnail for PIK3R1
    VM (1994). "Activation of the Eck receptor protein tyrosine kinase stimulates phosphatidylinositol 3-kinase activity". J. Biol. Chem. 269 (48): 30154–7...
    28 KB (3,136 words) - 20:06, 8 April 2024
  • Thumbnail for CHUK
    factor kappa-B kinase subunit alpha (IKK-α) also known as IKK1 or conserved helix-loop-helix ubiquitous kinase (CHUK) is a protein kinase that in humans...
    23 KB (2,765 words) - 20:13, 7 July 2024
  • Thumbnail for WWTR1
    YAP/TAZ. Tyrosine kinases signal in proliferative pathways, some which promote YAP/TAZ function, such as Src family kinases and includes the Yes tyrosine kinase...
    28 KB (2,383 words) - 05:52, 20 May 2024
  • Thumbnail for Neuregulin 1
    Neuregulin 1 (category Proteins)
    glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. It is known that an extraordinary variety...
    32 KB (3,921 words) - 10:13, 27 March 2024
  • receptor tyrosine kinase. Its structure includes an extracellular binding domain, a transmembrane lipophilic segment, and an intracellular tyrosine kinase domain...
    8 KB (834 words) - 16:25, 21 June 2024
  • Thumbnail for Restriction point
    their receptor tyrosine kinases (RTK) triggers a conformational change and promotes dimerization and autophosphorylation of tyrosine residues on the...
    22 KB (2,768 words) - 09:03, 4 July 2024
  • triple-helix protein that, like several other effectors, is targeted to the plasma membrane by N-myristoylation. AvrPto is an inhibitor of PRR kinase domains...
    16 KB (1,975 words) - 20:10, 5 July 2024
  • Thumbnail for Occludin
    YH, Lu Q, Goodenough DA, Jeansonne B (April 2002). "Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine...
    24 KB (2,898 words) - 06:03, 10 June 2024
  • Thumbnail for Adrenaline
    (AMP). Cyclic AMP activates protein kinase A. Protein kinase A phosphorylates and partially activates phosphorylase kinase. Adrenaline also binds to α1...
    57 KB (6,648 words) - 20:07, 29 July 2024
  • Thumbnail for ROCK1
    ROCK1 is a protein serine/threonine kinase also known as rho-associated, coiled-coil-containing protein kinase 1. Other common names are ROKβ and P160ROCK...
    20 KB (2,303 words) - 14:49, 9 July 2024
  • Thumbnail for CSNK1D
    member of the CK1 (formerly named casein kinase 1) family of serine/threonine specific eukaryotic protein kinases encompassing seven distinct isoforms (CK1α...
    118 KB (14,738 words) - 05:32, 3 June 2024
  • Thumbnail for Dopamine receptor
    receptors can also transactivate Receptor tyrosine kinases. Beta Arrestin recruitment is mediated by G-protein kinases that phosphorylate and inactivate dopamine...
    50 KB (5,330 words) - 03:50, 17 June 2024
  • PMID 29477613. S2CID 3534989. Rivera-Torres J, San José E (2019). "Src Tyrosine Kinase Inhibitors: New Perspectives on Their Immune, Antiviral, and Senotherapeutic...
    26 KB (2,028 words) - 10:24, 8 June 2024