Ubiquitin D is a protein that in humans is encoded by the UBD gene, also known as FAT10. UBD acts like ubiquitin, by covalently modifying proteins and...

Ubiquitin is a small (8.6 kDa) regulatory protein found in most tissues of eukaryotic organisms, i.e., it is found ubiquitously. It was discovered in...

Proteasomes are protein complexes which degrade ubiquitin-tagged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Enzymes that...

A ubiquitin ligase (also called an E3 ubiquitin ligase) is a protein that recruits an E2 ubiquitin-conjugating enzyme that has been loaded with ubiquitin...

proteins and biological fundamentals of the ubiquitin system. His current research continues to focus on the ubiquitin system and N-degron pathways. Varshavsky...

Ubiquitin is a protein that in humans is encoded by the UBB gene. Ubiquitin is one of the most conserved proteins known in eukaryotic organisms. Ubiquitin...

Ubiquitin carboxy-terminal hydrolase L1 (EC 3.1.2.15, ubiquitin C-terminal hydrolase, UCH-L1) is a deubiquitinating enzyme. UCH-L1 is a member of a gene...

In molecular biology, SUMO (Small Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other...

Ubiquitin-conjugating enzymes, also known as E2 enzymes and more rarely as ubiquitin-carrier enzymes, perform the second step in the ubiquitination reaction...

encoded by the UBC gene in humans. Polyubiquitin-C is one of the sources of ubiquitin, along with UBB, UBA52, and RPS27A. UBC gene is one of the two stress-regulated...

UBD may refer to: UBD, a gene which codes for the human protein Ubiquitin D United Baltic Duchy Use by date Universal Publishers (Australia) University...

Linear ubiquitin chain assembly complex (LUBAC) is a multi-protein complex and the only known E3 ubiquitin ligase able to conjugate ubiquitin in a head-to-tail...

Prokaryotic ubiquitin-like protein (Pup) is a functional analog of ubiquitin found in the prokaryote Mycobacterium tuberculosis. Like ubiquitin, Pup serves...

L40 (RPL40) is a protein that in humans is encoded by the UBA52 gene. Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major...

Ubiquitin-like proteins (UBLs) are a family of small proteins involved in post-translational modification of other proteins in a cell, usually with a...

Ubiquitin-associated (UBA) domains are protein domains that non-covalently interact with ubiquitin through protein-protein interactions. Ubiquitin is a...

on ubiquitin, a small protein involved in proteasomal protein degradation, Degrons may also be referred to as “ubiquitin-dependent" or “ubiquitin-independent"...

ubiquitin proteases, ubiquitin hydrolases, or ubiquitin isopeptidases, are a large group of proteases that cleave ubiquitin from proteins. Ubiquitin is...

Library of Medicine. "Entrez Gene: Deltex E3 ubiquitin ligase 4". Retrieved 2018-07-05. Cui J, Li Y, Zhu L, Liu D, Songyang Z, Wang HY, Wang RF (March 2012)...

Cullin, F-box containing complex (or SCF complex) is a multi-protein E3 ubiquitin ligase complex that catalyzes the ubiquitination of proteins destined...

Parkin is a 465-amino acid residue E3 ubiquitin ligase, a protein that in humans and mice is encoded by the PARK2 gene. Parkin plays a critical role in...

HERC2 is a giant E3 ubiquitin protein ligase, implicated in DNA repair regulation, pigmentation and neurological disorders. It is encoded by a gene of...

PMID 6305978. Hershko, A.; Leshinsky, E.; Ganoth, D.; Heller, H. (March 1, 1984). "ATP-dependent degradation of ubiquitin-protein conjugates". Proceedings of the...

enzymology, an ubiquitin-calmodulin ligase (EC 6.3.2.21) is an enzyme that catalyzes the chemical reaction n ATP + calmodulin + n ubiquitin ⇌ {\displaystyle...

gene, a part of the Cbl family, encodes the protein CBL which is an E3 ubiquitin-protein ligase involved in cell signalling and protein ubiquitination...

his Ph.D. in biochemistry in 1991. During his graduate education, Chen became interested in the biochemical pathway of the protein ubiquitin at a time...

damage, cyclin D (cyclin D1) is rapidly and transiently degraded by the proteasome upon its ubiquitylation by the CRL4-AMBRA1 ubiquitin ligase. This degradation...

Mouse double minute 2 homolog (MDM2) also known as E3 ubiquitin-protein ligase Mdm2 is a protein that in humans is encoded by the MDM2 gene. Mdm2 is an...

viral budding. Multivesicular body (MVB) biogenesis is a process in which ubiquitin-tagged proteins enter organelles called endosomes via the formation of...

the SUMO (small ubiquitin-like modifier) protein family. It is a ubiquitin-like protein and functions in a manner similar to ubiquitin in that it is bound...