Vemurafenib (INN), sold under the brand name Zelboraf, is a medication used for the treatment of late-stage melanoma. It is an inhibitor of the B-Raf...

developed. Two of these drugs, vemurafenib and dabrafenib, are approved by FDA for treatment of late-stage melanoma. Vemurafenib was the first approved drug...

metastatic melanoma with a BRAF V600E or V600K mutation, in combination with vemurafenib. It is also indicated for the treatment of adults with histiocytic neoplasms...

inconclusive results. There are two FDA-approved targeted drugs to treat ECD. Vemurafenib, an oral agent approved in 2019, targets the BRAF protein. It was approved...

Hyperkeratosis can also be caused by B-Raf inhibitor drugs such as vemurafenib and dabrafenib. It can be treated with urea-containing creams, which...

Etoposide Teniposide Tafluposide Bortezomib Erlotinib Gefitinib Imatinib Vemurafenib Vismodegib Azacitidine Azathioprine Capecitabine Cladribine Clofarabine...

monoclonal antibody approved to treat rheumatoid arthritis. 2011: Zelboraf (vemurafenib): For the treatment of metastatic melanoma caused by BRAF mutation. 2012:...

and vemurafenib 720 mg orally twice daily, or placebo in combination with cobimetinib 60 mg orally once daily (21 days on/7 days off) and vemurafenib 960 mg...

EGFR gene. Some drugs are specifically approved for certain genotypes. Vemurafenib is such a case which is used for melanoma patients who carry a mutation...

they are positive for the specific mutation. BRAF inhibitors, such as vemurafenib and dabrafenib and a MEK inhibitor trametinib are the most effective...

Cotreatment with CYP1A2 inhibitors like ciprofloxacin, fluvoxamine or vemurafenib can reduce chlorpromazine clearance and hence increase exposure and potentially...

additional $130 million in milestone payments, pending on the success of Vemurafenib (Plexxikon's lead program) an oral, novel drug that targets the oncogenic...

like ipilimumab, pembrolizumab, and nivolumab; BRAF inhibitors, such as vemurafenib and dabrafenib; or a MEK inhibitor trametinib may be used. When arising...

asthma, chronic idiopathic urticaria (CIU), and nasal polyps. Zelboraf (vemurafenib), for late-stage V600E BRAF mutation-positive melanoma. Zenapax (daclizumab)...

PARP inhibitor olaparib, veliparib -rafenib BRAF inhibitors sorafenib, vemurafenib -tinib Tyrosine-kinase inhibitors erlotinib, crizotinib -zomib proteasome...

plus encorafenib 450 mg once daily, encorafenib 300 mg once daily, or vemurafenib 960 mg twice daily. Treatment continued until disease progression or...

the rate of keratoacanthoma, such as the BRAF inhibitor medications vemurafenib and dabrafenib. Keratoacanthomas presents as a fleshy, elevated and nodular...

myasthenia gravis. The combination of ipilimumab with either leflunomide or vemurafenib may lead to increased hepatotoxicity. T lymphocytes can recognize and...

[D-Lys(6)]- LHRH, Phase II results for ovarian cancer. Braf inhibitors (vemurafenib, dabrafenib, LGX818) used to treat metastatic melanoma that harbors BRAF...

therapies for cancer, and in particular for his work on the melanoma drug vemurafenib. In 2013, Massachusetts General Hospital partnered with AstraZeneca to...

ipilimumab, pembrolizumab, nivolumab, cemiplimab; BRAF inhibitors, such as vemurafenib and dabrafenib; and a MEK inhibitor trametinib. In February 2024, the...

include SB590885, PLX4720, XL281, RAF265, encorafenib, dabrafenib, and vemurafenib. Some MEK inhibitors include cobimetinib, CI-1040, PD0325901, binimetinib...

targeting agent. It is also being studied for use in combination with vemurafenib in patients with advanced BRAF V600-mutant solid tumors. "Tunlametinib"...

vincristine, vindesine, imatinib, irinotecan, sorafenib, sunitinib, vemurafenib, temsirolimus, anastrozole, gefitinib; azole antifungals: ketoconazole...

quinine Antibiotics macrolides fluoroquinolones Other drugs methadone vemurafenib pitolisant fluconazole Some second-generation antihistamines, such as...

survival and has been approved by the FDA. Another similar combination is vemurafenib and cobimetinib. Immunotherapy is also starting to play an important...

agents ipilimumab, pembrolizumab, and nivolumab; BRAF inhibitors, such as vemurafenib and dabrafenib; and a MEK inhibitor trametinib. Important prognosis factors...

L01EB09 Lazertinib L01EB10 Mobocertinib L01EB11 Aumolertinib L01EC01 Vemurafenib L01EC02 Dabrafenib L01EC03 Encorafenib L01ED01 Crizotinib L01ED02 Ceritinib...

or XL518, approved by US FDA in Nov 2015 for use in combination with vemurafenib (Zelboraf(R)), for treatment of advanced melanoma with a BRAF V600E or...

Lapatinib Neratinib Tucatinib BRAF Dabrafenib Encorafenib Tovorafenib Vemurafenib RTK class III: C-kit and PDGFR (Avapritinib Axitinib Masitinib Pazopanib...