• cellular biology, the Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through...
    64 KB (7,432 words) - 08:21, 28 October 2024
  • Thumbnail for Paracrine signaling
    cellular biology, paracrine signaling is a form of cell signaling, a type of cellular communication in which a cell produces a signal to induce changes in nearby...
    45 KB (4,879 words) - 07:05, 7 April 2025
  • de-regulated Wnt signaling pathway reduces proliferation and survival of cancer. These findings suggest that interference with Wnt signaling at the ligand-receptor...
    18 KB (2,105 words) - 01:40, 20 August 2024
  • Thumbnail for Notch signaling pathway
    The Notch signaling pathway is a highly conserved cell signaling system present in most animals. Mammals possess four different notch receptors, referred...
    95 KB (11,032 words) - 23:25, 20 February 2025
  • A biochemical cascade, also known as a signaling cascade or signaling pathway, is a series of chemical reactions that occur within a biological cell when...
    99 KB (11,432 words) - 04:27, 2 November 2024
  • Thumbnail for Protein Wnt-5a
    mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling". Molecular and Cellular Biology. 23 (1): 131–9...
    29 KB (3,404 words) - 03:05, 11 July 2024
  • WNT or Wnt may refer to: Windows NT WNT (Women's National Team) Wnt signaling pathway, a complex protein network The Weymouth New Testament (1902), translation...
    655 bytes (109 words) - 16:27, 22 December 2021
  • Thumbnail for Catenin beta-1
    Catenin beta-1 (category Signal transduction)
    cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous...
    107 KB (12,347 words) - 14:08, 17 March 2025
  • Thumbnail for Apc, wnt signaling pathway regulator
    APC, WNT signaling pathway regulator is a protein that in humans is encoded by the APC gene. This gene encodes a tumor suppressor protein that acts as...
    4 KB (617 words) - 19:39, 29 February 2024
  • Thumbnail for TCF/LEF family
    a SOX-like high mobility group domain. They are involved in the Wnt signaling pathway, particularly during embryonic and stem-cell development, but also...
    17 KB (2,039 words) - 02:50, 29 November 2024
  • Thumbnail for Dishevelled
    is a family of proteins involved in canonical and non-canonical Wnt signalling pathways. Dsh (Dvl in mammals) is a cytoplasmic phosphoprotein that acts...
    12 KB (1,387 words) - 16:33, 27 February 2025
  • The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different...
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  • signalling pathway PI3K/AKT/mTOR signalling pathway TGF beta signalling pathway TLR signalling pathway VEGF signalling pathway Wnt signalling pathway...
    1,014 bytes (86 words) - 23:23, 19 January 2023
  • Thumbnail for Frizzled
    protein-coupled receptors that serve as receptors in the Wnt signaling pathway and other signaling pathways. When activated, Frizzled leads to activation of Dishevelled...
    7 KB (809 words) - 05:58, 13 May 2024
  • Thumbnail for Presenilin-1
    collectively suggest a critical role of presenilin 1 in the Notch signaling pathway. Wnt signaling pathway has been shown to be involved in several critical steps...
    25 KB (3,113 words) - 02:12, 20 January 2025
  • The Akt signaling pathway or PI3K-Akt signaling pathway is a signal transduction pathway that promotes survival and growth in response to extracellular...
    36 KB (4,072 words) - 15:49, 12 April 2025
  • Thumbnail for Sonic hedgehog protein
    protein (SHH) is a major signaling molecule of embryonic development in humans and animals, encoded by the SHH gene. This signaling molecule is key in regulating...
    63 KB (7,452 words) - 18:59, 21 April 2025
  • Thumbnail for Proto-oncogene Wnt-1
    another family member, WNT10B, in the chromosome 12q13 region. Wnt signaling pathway GRCh38: Ensembl release 89: ENSG00000125084 – Ensembl, May 2017...
    9 KB (1,008 words) - 17:50, 10 April 2024
  • Thumbnail for Glycogen synthase kinase-3 beta
    rtPA-induced hemorrhagic transformation and activates the Wnt/β-catenin signaling pathway after acute ischemic stroke in rats". Molecular Neurobiology...
    17 KB (1,819 words) - 16:52, 22 May 2024
  • Thumbnail for LRP5
    Reduction of canonical Wnt signals upon depletion of LRP5 and LRP6 results in p120-catenin degradation. The Wnt signaling pathway was first linked to bone...
    24 KB (3,205 words) - 23:28, 18 December 2024
  • Thumbnail for Adenomatous polyposis coli
    attachment and signaling. The activity of one protein in particular, beta-catenin, is controlled by the APC protein (see: Wnt signaling pathway). Regulation...
    28 KB (3,227 words) - 14:23, 29 March 2025
  • Thumbnail for WNT4
    WNT4 (redirect from Wnt-4)
    female to male sex reversal. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been...
    26 KB (3,079 words) - 19:38, 15 February 2025
  • Thumbnail for Secreted frizzled-related protein 1
    also able to downregulate Wnt signaling by the formation of an inhibitory complex with the Frizzled receptors. The Wnt pathway plays a key role in embryonic...
    48 KB (6,321 words) - 23:57, 9 November 2024
  • JAK-STAT signaling pathway Imd pathway Localisation signal Oscillation Protein dynamics Systems biology Lipid signaling Redox signaling Signaling cascade...
    61 KB (6,650 words) - 06:31, 20 April 2025
  • Thumbnail for Primitive streak
    (1997). "The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation". Cell. 90 (1): 181–92....
    23 KB (2,803 words) - 06:48, 25 October 2024
  • Thumbnail for DKK1
    embryonic development through its inhibition of the Wnt signaling pathway. Dickkopf WNT signaling pathway inhibitor 1 (Dkk1) is a protein-coding gene that...
    16 KB (1,886 words) - 08:50, 17 May 2024
  • Thumbnail for R-spondin 1
    female to male sex reversal. Furthermore, it promotes canonical WNT/β catenin signaling. The protein has two cysteine-rich, furin-like domains and one...
    8 KB (913 words) - 08:19, 29 December 2024
  • Thumbnail for DKK3
    involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer...
    8 KB (918 words) - 11:28, 24 December 2023
  • Samumed's products in development target novel components of the Wnt signaling pathway. The company focuses on potential treatments for several diseases;...
    3 KB (156 words) - 14:46, 21 March 2025
  • Thumbnail for Lymphoid enhancer-binding factor 1
    Wnt signaling pathway, whose ligands are highly expressed in tumors. Recently, some of the upstream molecules present in this Wnt signaling pathway have...
    31 KB (3,903 words) - 15:33, 16 March 2025