• Thumbnail for 4-Hydroxycoumarin
    4-Hydroxycoumarin is a coumarin derivative with a hydroxy group at the 4-position. 4-Hydroxycoumarin is an important fungal metabolite from the precursor...
    3 KB (239 words) - 12:08, 14 January 2024
  • Thumbnail for 4-Hydroxycoumarins
    4-Hydroxycoumarins are a class of vitamin K antagonist (VKA) anticoagulant drug molecules. Chemically, they are derived from coumarin by adding a hydroxy...
    7 KB (633 words) - 19:30, 21 April 2024
  • Hydroxycoumarin may refer to: 4-Hydroxycoumarin 7-Hydroxycoumarin (umbelliferone) This set index article lists chemical compounds articles associated...
    412 bytes (43 words) - 11:46, 9 November 2023
  • 4-hydroxycoumarin synthase (EC 2.3.1.208, BIS2, BIS3) is an enzyme with systematic name malonyl-CoA:2-hydroxybenzoyl-CoA malonyltransferase. This enzyme...
    1 KB (101 words) - 12:41, 26 August 2023
  • Thumbnail for Dipteryx odorata
    anticoagulant prescription drugs, such as warfarin, are based on 4-hydroxycoumarin, a chemical derivative of coumarin initially isolated from this bean...
    13 KB (1,402 words) - 15:40, 14 August 2024
  • Thumbnail for Michael addition reaction
    A well-known Michael reaction is the synthesis of warfarin from 4-hydroxycoumarin and benzylideneacetone first reported by Link in 1944: Several asymmetric...
    27 KB (2,825 words) - 08:27, 20 March 2024
  • Thumbnail for Coumarin derivatives
    considered phenylpropanoids. Among the most important derivatives are the 4-hydroxycoumarins, which exhibit anticoagulant properties, a characteristic not present...
    9 KB (881 words) - 18:55, 21 April 2024
  • Thumbnail for Coumarin
    incorrectly referred to as "coumadins" rather than 4-hydroxycoumarins. Some of the 4-hydroxycoumarin anticoagulant class of chemicals are designed to have...
    36 KB (2,940 words) - 20:34, 13 June 2024
  • Thumbnail for Brodifacoum
    Brodifacoum (category 4-Hydroxycoumarins)
    Brodifacoum is a highly lethal 4-hydroxycoumarin vitamin K antagonist anticoagulant poison. In recent years, it has become one of the world's most widely...
    24 KB (2,188 words) - 15:31, 3 August 2024
  • Thumbnail for Warfarin
    Warfarin (category 4-Hydroxycoumarins)
    which is formed from the 4-hydroxycoumarin and the ketone in the 3-position substituent. However, the existence of many 4-hydroxycoumadin anticoagulants...
    94 KB (9,772 words) - 05:31, 19 April 2024
  • Thumbnail for Rodenticide
    addition to this specific metabolic disruption, massive toxic doses of 4-hydroxycoumarin, 4-thiochromenone and 1,3-indandione anticoagulants cause damage to...
    28 KB (3,006 words) - 17:19, 8 June 2024
  • Thumbnail for Vitamin K antagonist
    can cause birth defects (teratogens). Coumarins (more accurately 4-hydroxycoumarins) are the most commonly used VKAs. In medicine, the most commonly used...
    13 KB (1,458 words) - 15:57, 21 May 2024
  • Thumbnail for Bromadiolone
    Bromadiolone (category 4-Hydroxycoumarins)
    is a potent anticoagulant rodenticide. It is a second-generation 4-hydroxycoumarin derivative and vitamin K antagonist, often called a "super-warfarin"...
    6 KB (394 words) - 21:29, 4 February 2024
  • Thumbnail for Dicoumarol
    Dicoumarol (category 4-Hydroxycoumarins)
    history. Identified in 1940, dicoumarol became the prototype of the 4-hydroxycoumarin anticoagulant drug class. Dicoumarol itself, for a short time, was...
    7 KB (702 words) - 17:18, 18 June 2024
  • Thumbnail for Coumatetralyl
    Coumatetralyl (category 4-Hydroxycoumarins)
    Coumatetralyl is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type used as a rodenticide. Coumatetralyl is commonly used with grains...
    4 KB (207 words) - 00:54, 17 February 2023
  • acids include bisphenol A, parabens, 1,2,3-triazole derivates, and 4-hydroxycoumarin and act as proton donors, changing the dye molecule between its leuco...
    23 KB (2,740 words) - 13:15, 6 August 2024
  • Thumbnail for Difenacoum
    Difenacoum (category 4-Hydroxycoumarins)
    Difenacoum is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type. It has anticoagulant effects and is used commercially as a rodenticide...
    5 KB (370 words) - 15:34, 31 May 2024
  • Thumbnail for Vitamin K
    subset, 4-hydroxycoumarins, act as vitamin K antagonists. They block the regeneration and recycling of vitamin K. Some of the 4-hydroxycoumarin anticoagulant...
    69 KB (7,760 words) - 11:23, 19 August 2024
  • Thumbnail for Acenocoumarol
    Acenocoumarol (category 4-Hydroxycoumarins)
    Hepatic Elimination half-life 8 to 11 hours Identifiers IUPAC name (RS)-4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one CAS Number 152-72-7 Y PubChem...
    3 KB (192 words) - 22:22, 7 January 2024
  • Thumbnail for Phenprocoumon
    Phenprocoumon (category 4-Hydroxycoumarins)
    influence the dose needed to achieve the desired INR. Phenprocoumon, a 4-hydroxycoumarin structurally similar to warfarin, is a white to off-white crystalline...
    18 KB (1,895 words) - 11:18, 28 January 2024
  • Thumbnail for Flocoumafen
    Flocoumafen (category 4-Hydroxycoumarins)
    Flocoumafen is a fluorinated, second-generation anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type. It is a second generation (i.e., high potency)...
    3 KB (211 words) - 19:46, 2 April 2024
  • Thumbnail for Warfarin necrosis
    deficiency following treatment with anti-vitamin K anticoagulants (4-hydroxycoumarins, such as warfarin). Warfarin necrosis is a rare but severe complication...
    11 KB (1,332 words) - 18:31, 11 March 2023
  • Thumbnail for Benzylideneacetone
    benzylideneacetone results in a preparation of benzylacetone. The reaction of 4-Hydroxycoumarin with this compound yields Warfarin. Claisen, L. "Über die Einwirkung...
    6 KB (477 words) - 19:32, 27 October 2022
  • Thumbnail for Triacetic acid lactone
    is used for metal extraction and plating and as a food additive. 4-Hydroxycoumarin - bicyclic analogue "New Sustainable Production Method Could Advance...
    6 KB (512 words) - 04:51, 10 November 2023
  • Thumbnail for Organocatalysis
    warfarin (in equilibrium with the hemiketal) in a Michael addition of 4-hydroxycoumarin and benzylideneacetone: A recent exploit is the vinyl alkylation of...
    17 KB (1,720 words) - 11:46, 11 May 2024
  • chromatographic method for the estimation of phenprocoumon, 3-(1-phenyl-propyl)-4-hydroxycoumarin (marcoumar®, liquamar®), in human serum or plasma". Clinica Chimica...
    10 KB (880 words) - 01:16, 12 June 2024
  • Thumbnail for 3-Azidocoumarin
    3-azidocoumarin. The isomeric 4-azidocoumarin (CAS# 42373-56-8) product can also be prepared from 4-hydroxycoumarin via the 4-chloro derivative, which reacts...
    4 KB (368 words) - 11:36, 13 January 2024
  • and tested it; it turned out to be dicoumarol (3,3'-methylenebis-(4 hydroxycoumarin)). Dicoumarol was subjected to clinical trials in Wisconsin General...
    7 KB (801 words) - 18:20, 5 October 2023
  • synthase EC 2.3.1.208: 4-hydroxycoumarin synthase EC 2.3.1.209: dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase EC 2.3.1.210: dTDP-4-amino-4,6-dideoxy-D-galactose...
    215 KB (21,664 words) - 23:41, 8 May 2024
  • 031694 u) may refer to: Umbelliferone, also known as 7-hydroxycoumarin or hydrangine 4-Hydroxycoumarin This set index page lists chemical structure articles...
    340 bytes (63 words) - 00:07, 31 March 2021