5-Methylcytosine is a methylated form of the DNA base cytosine (C) that regulates gene transcription and takes several other biological roles. When cytosine...
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Methylcytosine may refer to: 5-Methylcytosine 1-Methylcytosine, a nucleic acid in Hachimoji DNA N(4)-Methylcytosine 6-Methylcytosine Cytosine Nucleic acid...
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Deamination (section 5-methylcytosine)
vitro through the use of bisulfite, which deaminates cytosine, but not 5-methylcytosine. This property has allowed researchers to sequence methylated DNA to...
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and cytosine. The modified bases are N6-methyladenine, 5-methylcytosine and N4-methylcytosine. Cytosine methylation is widespread in both eukaryotes and...
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oxidation of 5-methylcytosine, a reaction mediated by TET enzymes. Its molecular formula is C5H7N3O2. Every mammalian cell seems to contain 5-Hydroxymethylcytosine...
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Modified Cytosine N4-Methylcytosine 5-Carboxylcytosine 5-Formylcytosine 5-Glycosylhydroxymethylcytosine 5-Hydroxycytosine 5-Methylcytosine Modified Thymidine...
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Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) is a member of the TET family of enzymes, in humans it is encoded by the TET1 gene. Its function...
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groups to the DNA, mostly at CpG sites, to convert cytosine to 5-methylcytosine. 5-Methylcytosine performs much like a regular cytosine, pairing with a guanine...
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also be methylated into 5-methylcytosine by an enzyme called DNA methyltransferase or be methylated and hydroxylated to make 5-hydroxymethylcytosine. The...
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modified DNA base methylcytosine to 5-hydroxymethylcytosine. The first mechanistic reports showed tissue-specific accumulation of 5-hydroxymethylcytosine...
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Methylation (redirect from 5-O-Methylation)
present in eukaryotes. 5-methylcytosine (5-mC) also commonly occurs in various RNA molecules. Recent data strongly suggest that m6A and 5-mC RNA methylation...
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ten-eleven translocation (TET) methylcytosine dioxygenases. They are instrumental in DNA demethylation. 5-Methylcytosine (see first Figure) is a methylated...
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acid chain has been formed. In DNA, the most common modified base is 5-methylcytosine (m5C). In RNA, there are many modified bases, including those contained...
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islands. Cytosines in CpG dinucleotides can be methylated to form 5-methylcytosines. Enzymes that add a methyl group are called DNA methyltransferases...
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DNA cytosine to form 5-methylcytosine. This usually occurs in the DNA sequence CpG, changing the DNA at the CpG site from CpG to 5-mCpG. Methylation of...
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5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine. It is found in ribonucleic acids of animal, plant, and bacterial origin. Dunn...
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Bisulfite sequencing (section 5-Hydroxymethylcytosine)
DNA with bisulfite converts cytosine residues to uracil, but leaves 5-methylcytosine residues unaffected. Therefore, DNA that has been treated with bisulfite...
34 KB (4,084 words) - 21:59, 8 January 2024
molecular biology in mammals, DNA demethylation causes replacement of 5-methylcytosine (5mC) in a DNA sequence by cytosine (C) (see figure of 5mC and C)....
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modifications include DNA cytosine methylation to form 5-methylcytosine and 5-methylcytosine demethylation. These modifications are critical for cell...
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deamination of guanine. (Thymidine products following deamination of 5-methylcytosine are more difficult to recognize, but can be repaired by mismatch-specific...
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cytosine reacted much faster to sodium bisulfite treatment than did 5-methylcytosine. This difference in reaction rates created the possibility of identifying...
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central roles of ten-eleven translocation methylcytosine dioxygenases (TETs) in the demethylation of 5-methylcytosine to form cytosine. As reviewed in 2018...
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pathways illustrated in the Figure below, titled "Demethylation of 5-Methylcytosine (5mC) in neuron DNA," especially the TET dependent pathway, have been...
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into uracil, but does not affect 5-methylcytosine, a methylated form of cytosine with a methyl group attached to carbon 5. When the bisulfite-treated DNA...
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formula is C5H5N3O2. Similarly to the related cytosine modifications 5-Methylcytosine (5mC) and 5hmC, 5fC is broadly distributed across the mammalian genome...
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modifications include DNA cytosine methylation to form 5-methylcytosine and 5-methylcytosine demethylation. These modifications are critical for cell...
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(where 5' cytosine is followed by 3' guanine or CpG sites). 5-methylcytosine (5-mC) is a methylated form of the DNA base cytosine (see Figure). 5-mC is...
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messenger RNA from its target gene. 5-Methylcytosine (5-mC) is a methylated form of the DNA base cytosine (see figure). 5-mC is an epigenetic marker found...
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form 5-methylcytosine and 5-methylcytosine demethylation. DNA cytosine methylation is catalyzed by DNA methyltransferases (DNMTs). Methylcytosine demethylation...
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developed that incorporate modified nucleoside substitutions such as 5-methylcytosine, 5-methyluridine, N1-methylpseudouridine (the same nucleoside used in...
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