• A BBSome is a protein complex that operates in primary cilia biogenesis, homeostasis, and intraflagellar transport (IFT). The BBSome recognizes cargo proteins...
    53 KB (6,700 words) - 03:20, 27 July 2024
  • Thumbnail for Bardet–Biedl syndrome
    BBS proteins are assembled into a multiple protein complex, called "BBSome". BBSome is proposed to be responsible for transporting intracellular vesicles...
    15 KB (1,432 words) - 05:31, 17 June 2024
  • observed to drive the oligomerization of the BBS2 and BBS7 subunits of the BBSome. Because coiled-coils generally interact with other coiled coils, they are...
    34 KB (3,860 words) - 13:37, 5 October 2024
  • Thumbnail for BBS1
    protein that in humans is encoded by the BBS1 gene. BBS1 is part of the BBSome complex, which required for ciliogenesis. Mutations in this gene have been...
    6 KB (784 words) - 13:28, 18 October 2022
  • Thumbnail for LZTFL1
    (November 2011). "A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened". PLOS Genetics. 7 (11): e1002358. doi:10.1371/journal.pgen...
    7 KB (563 words) - 07:26, 27 September 2024
  • Thumbnail for BBS9
    molecular function Cellular component cytoplasm cytosol cell projection BBSome pericentriolar material membrane plasma membrane cilium centriolar satellite...
    4 KB (498 words) - 06:59, 27 March 2022
  • Thumbnail for BBS5
    binding protein binding Cellular component cytoplasm cytosol cell projection BBSome membrane plasma membrane cilium intracellular anatomical structure microtubule...
    8 KB (707 words) - 01:07, 29 April 2024
  • Thumbnail for BBS2
    Cellular component cytoplasm ciliary basal body cytosol cell projection BBSome membrane plasma membrane cilium microtubule organizing center ciliary membrane...
    7 KB (687 words) - 04:33, 30 January 2023
  • Thumbnail for BBS7
    component cytoplasm ciliary basal body cytosol centrosome cell projection BBSome membrane plasma membrane photoreceptor outer segment cilium microtubule...
    4 KB (546 words) - 21:55, 18 August 2023
  • Thumbnail for TTC8
    cilium cytoskeleton membrane ciliary membrane microtubule organizing center BBSome non-motile cilium photoreceptor connecting cilium Biological process protein...
    5 KB (634 words) - 12:09, 17 January 2024
  • cilia, intraflagellar transport proteins such as IFT57 and ARF4 while the BBSome does not appear to interact with the sequence. The kinesins KIF17 is implicated...
    14 KB (1,462 words) - 04:36, 26 April 2024
  • Thumbnail for BBS4
    Cellular component cytoplasm ciliary basal body centrosome cell projection BBSome pericentriolar material membrane photoreceptor inner segment plasma membrane...
    6 KB (775 words) - 01:56, 4 March 2023
  • Thumbnail for ARL6
    binding GTPase activity Cellular component cytoplasm cytosol cell projection BBSome membrane plasma membrane intracellular anatomical structure axoneme membrane...
    6 KB (846 words) - 18:52, 25 April 2024