• Thumbnail for Bcl-2-like protein 1
    Bcl-2-like protein 1 is a protein encoded in humans by the BCL2L1 gene. Through alternative splicing, the gene encodes both of the human proteins Bcl-xL...
    19 KB (2,223 words) - 05:29, 3 January 2024
  • Thumbnail for Bcl-2
    Bcl-2, encoded in humans by the BCL2 gene, is the founding member of the Bcl-2 family of regulator proteins. BCL2 blocks programmed cell death (apoptosis)...
    41 KB (4,564 words) - 10:38, 29 September 2024
  • Thumbnail for Bcl-2 family
    The Bcl-2 family (TC# 1.A.21) consists of a number of evolutionarily-conserved proteins that share Bcl-2 homology (BH) domains. The Bcl-2 family is most...
    16 KB (2,160 words) - 15:15, 1 October 2024
  • Thumbnail for Apoptosis regulator BAX
    regulator BAX, also known as bcl-2-like protein 4, is a protein that in humans is encoded by the BAX gene. BAX is a member of the Bcl-2 gene family. BCL2 family...
    18 KB (2,092 words) - 06:47, 29 September 2024
  • Thumbnail for Bcl-xL
    large (Bcl-xL), encoded by the BCL2-like 1 gene, is a transmembrane molecule in the mitochondria. It is a member of the Bcl-2 family of proteins, and acts...
    7 KB (884 words) - 21:39, 24 July 2024
  • Thumbnail for Phorbol-12-myristate-13-acetate-induced protein 1
    has been shown to interact with: BCL2-like 1, Bcl-2, and MCL1. Apoptosis Apoptosome Bcl-2 Bcl-2-associated X protein (BAX) BH3 interacting domain death agonist...
    11 KB (1,311 words) - 12:34, 19 July 2024
  • Thumbnail for Bcl-2 homologous antagonist killer
    Bcl-2 homologous antagonist/killer is a protein which in humans is encoded by the BAK1 gene on chromosome 6. It belongs to the BCL2 protein family. BCL2...
    21 KB (2,597 words) - 09:19, 7 July 2024
  • Thumbnail for BCL2L11
    BCL2L11 (redirect from BCL2-like 11)
    Bcl-2-like protein 11, commonly called BIM (Bcl-2 Interacting Mediator of cell death), is a protein that in humans is encoded by the BCL2L11 gene. The...
    11 KB (1,403 words) - 16:01, 15 March 2024
  • Thumbnail for Bcl-2-interacting killer
    Bcl-2-interacting killer is a protein that in humans is encoded by the BIK gene. The protein encoded by this gene is known to interact with cellular and...
    10 KB (1,379 words) - 00:47, 2 December 2023
  • the mitochondria. The Bcl-2 family of proteins can either inhibit or promote apoptosis and members are characterized by the Bcl-2 homologous domains BH1...
    13 KB (1,572 words) - 12:11, 13 September 2024
  • Thumbnail for BCL2L2
    BCL2L2 (redirect from Bcl-w)
    Bcl-2-like protein 2 is a 193-amino acid protein that in humans is encoded by the BCL2L2 gene on chromosome 14 (band q11.2-q12). It was originally discovered...
    13 KB (1,552 words) - 06:07, 15 January 2024
  • Thumbnail for Glucagon-like peptide-1 receptor
    The glucagon-like peptide-1 receptor (GLP1R) is a G protein-coupled receptor (GPCR) found on beta cells of the pancreas and on neurons of the brain. It...
    33 KB (4,119 words) - 09:50, 28 October 2024
  • Thumbnail for Peripheral membrane protein
    They may also occur in BcL-2 like protein , in some amphiphilic antimicrobial peptides , and in certain annexins . These proteins are usually described...
    55 KB (4,414 words) - 20:08, 7 October 2024
  • Thumbnail for Protein kinase B
    is a pro-apoptotic protein of the Bcl-2 family. Akt1 can phosphorylate BAD on Ser136, which makes BAD dissociate from the Bcl-2/Bcl-X complex and lose...
    35 KB (3,831 words) - 18:08, 20 August 2024
  • Thumbnail for BECN1
    BECN1 (redirect from Beclin 1)
    This protein interacts with either BCL-2 or PI3k class III, playing a critical role in the regulation of both autophagy and cell death. Beclin-1 plays...
    13 KB (1,482 words) - 16:14, 15 March 2024
  • Thumbnail for Follicular hyperplasia
    its polyclonality and lack of bcl-2 protein expression, whereas follicular lymphoma is monoclonal, and expresses bcl-2. Lymphadenopathies such as follicular...
    19 KB (2,205 words) - 03:58, 23 September 2023
  • Ced-9 (category Protein pages needing a picture)
    CED-9 protein found as an Integral membrane protein in the mitochondrial membrane. The protein is homologous to the human apoptotic regulator Bcl-2 as well...
    15 KB (1,798 words) - 11:20, 18 August 2023
  • Thumbnail for BNIP3
    BNIP3 (category Protein families)
    kDa protein-interacting protein 3 is a protein found in humans that is encoded by the BNIP3 gene. BNIP3 is a member of the apoptotic Bcl-2 protein family...
    21 KB (2,672 words) - 04:34, 2 November 2024
  • chain gene enhancer and results in the overexpression of the Bcl-2 protein. Bcl-2 proteins prevent the activation of the caspases that lead to programmed...
    20 KB (2,453 words) - 10:36, 1 June 2024
  • Thumbnail for Apoptosis
    as cancer. Some factors like Fas receptors and caspases promote apoptosis, while some members of the Bcl-2 family of proteins inhibit apoptosis. German...
    91 KB (10,639 words) - 09:36, 29 October 2024
  • Thumbnail for Cyclin-dependent kinase 1
    kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine protein kinase...
    25 KB (2,896 words) - 12:38, 29 August 2024
  • Thumbnail for BNIP3L
    Okuyama A, Tsujimoto Y (1999). "Bcl-2/E1B 19 kDa-interacting protein 3-like protein (Bnip3L) interacts with bcl-2/Bcl-xL and induces apoptosis by altering...
    7 KB (880 words) - 16:18, 13 October 2022
  • Adenovirus E1B protein usually refers to one of two proteins transcribed from the E1B gene of the adenovirus: a 55kDa protein and a 19kDa protein. These two...
    8 KB (952 words) - 08:49, 29 December 2023
  • Thumbnail for Protein C
    activation of caspase 3 and caspase 8, improved Bax/Bcl-2 ratio and down-regulation of p53.: 2388  Activated protein C also provides much protection of endothelial...
    47 KB (5,346 words) - 02:39, 28 October 2024
  • Thumbnail for APAF1
    APAF1 (redirect from Apaf-1)
    large proteins in vitro". DNA Research. 4 (5): 307–13. doi:10.1093/dnares/4.5.307. PMID 9455477. Pan G, O'Rourke K, Dixit VM (Mar 1998). "Caspase-9, Bcl-XL...
    14 KB (1,677 words) - 05:51, 1 January 2024
  • Thumbnail for IGFBP3
    IGF binding proteins (IGFBP-1 to IGFBP-6) that have highly conserved structures and bind the insulin-like growth factors IGF-1 and IGF-2 with high affinity...
    39 KB (4,717 words) - 13:09, 2 June 2024
  • Thumbnail for Fas ligand
    protein Bid into its truncated form, tBid. BH-3 only members of the Bcl-2 family engage exclusively anti-apoptotic members of the family (Bcl-2, Bcl-xL)...
    22 KB (2,547 words) - 08:19, 11 August 2024
  • Thumbnail for Insulin receptor substrate 1
    activity) with: Bcl-2, Grb2, INSR, IGF1R, JAK1, JAK2, MAPK8, PIK3R1 PIK3R3, PTK2, PTPN11, PTPN1, and YWHAE. IRS-1, as a signalling adapter protein, is able to...
    34 KB (4,304 words) - 07:20, 3 September 2024
  • Thumbnail for C20orf144
    C20orf144 (section Protein)
    protein-encoding gene. The human c20orf144 protein consists of 153 amino acids, with the first 150 amino acids being characterized as part of the Bcl-2...
    11 KB (743 words) - 15:38, 9 May 2024
  • Thumbnail for BCL2L14
    facilitator Bcl-2-like protein 14 is a protein that in humans is encoded by the BCL2L14 gene. The protein encoded by this gene belongs to the BCL2 protein family...
    5 KB (676 words) - 00:47, 2 December 2023