Bcl-2-like protein 1 is a protein encoded in humans by the BCL2L1 gene. Through alternative splicing, the gene encodes both of the human proteins Bcl-xL...
19 KB (2,223 words) - 05:29, 3 January 2024
Bcl-2, encoded in humans by the BCL2 gene, is the founding member of the Bcl-2 family of regulator proteins. BCL2 blocks programmed cell death (apoptosis)...
41 KB (4,564 words) - 10:38, 29 September 2024
The Bcl-2 family (TC# 1.A.21) consists of a number of evolutionarily-conserved proteins that share Bcl-2 homology (BH) domains. The Bcl-2 family is most...
16 KB (2,160 words) - 15:15, 1 October 2024
Apoptosis regulator BAX (redirect from Bcl-2–associated death protein)
regulator BAX, also known as bcl-2-like protein 4, is a protein that in humans is encoded by the BAX gene. BAX is a member of the Bcl-2 gene family. BCL2 family...
18 KB (2,092 words) - 06:47, 29 September 2024
large (Bcl-xL), encoded by the BCL2-like 1 gene, is a transmembrane molecule in the mitochondria. It is a member of the Bcl-2 family of proteins, and acts...
7 KB (884 words) - 21:39, 24 July 2024
has been shown to interact with: BCL2-like 1, Bcl-2, and MCL1. Apoptosis Apoptosome Bcl-2 Bcl-2-associated X protein (BAX) BH3 interacting domain death agonist...
11 KB (1,311 words) - 12:34, 19 July 2024
Bcl-2 homologous antagonist/killer is a protein which in humans is encoded by the BAK1 gene on chromosome 6. It belongs to the BCL2 protein family. BCL2...
21 KB (2,597 words) - 09:19, 7 July 2024
BCL2L11 (redirect from BCL2-like 11)
Bcl-2-like protein 11, commonly called BIM (Bcl-2 Interacting Mediator of cell death), is a protein that in humans is encoded by the BCL2L11 gene. The...
11 KB (1,403 words) - 16:01, 15 March 2024
Bcl-2-interacting killer is a protein that in humans is encoded by the BIK gene. The protein encoded by this gene is known to interact with cellular and...
10 KB (1,379 words) - 00:47, 2 December 2023
Inhibitor of apoptosis (redirect from Inhibitor of apoptosis protein)
the mitochondria. The Bcl-2 family of proteins can either inhibit or promote apoptosis and members are characterized by the Bcl-2 homologous domains BH1...
13 KB (1,572 words) - 12:11, 13 September 2024
The glucagon-like peptide-1 receptor (GLP1R) is a G protein-coupled receptor (GPCR) found on beta cells of the pancreas and on neurons of the brain. It...
33 KB (4,119 words) - 09:50, 28 October 2024
They may also occur in BcL-2 like protein , in some amphiphilic antimicrobial peptides , and in certain annexins . These proteins are usually described...
55 KB (4,414 words) - 20:08, 7 October 2024
is a pro-apoptotic protein of the Bcl-2 family. Akt1 can phosphorylate BAD on Ser136, which makes BAD dissociate from the Bcl-2/Bcl-X complex and lose...
35 KB (3,831 words) - 18:08, 20 August 2024
its polyclonality and lack of bcl-2 protein expression, whereas follicular lymphoma is monoclonal, and expresses bcl-2. Lymphadenopathies such as follicular...
19 KB (2,205 words) - 03:58, 23 September 2023
Ced-9 (category Protein pages needing a picture)
CED-9 protein found as an Integral membrane protein in the mitochondrial membrane. The protein is homologous to the human apoptotic regulator Bcl-2 as well...
15 KB (1,798 words) - 11:20, 18 August 2023
BNIP3 (category Protein families)
kDa protein-interacting protein 3 is a protein found in humans that is encoded by the BNIP3 gene. BNIP3 is a member of the apoptotic Bcl-2 protein family...
21 KB (2,672 words) - 04:34, 2 November 2024
chain gene enhancer and results in the overexpression of the Bcl-2 protein. Bcl-2 proteins prevent the activation of the caspases that lead to programmed...
20 KB (2,453 words) - 10:36, 1 June 2024
Apoptosis (redirect from Apoptosis regulatory proteins)
as cancer. Some factors like Fas receptors and caspases promote apoptosis, while some members of the Bcl-2 family of proteins inhibit apoptosis. German...
91 KB (10,639 words) - 09:36, 29 October 2024
kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine protein kinase...
25 KB (2,896 words) - 12:38, 29 August 2024
Okuyama A, Tsujimoto Y (1999). "Bcl-2/E1B 19 kDa-interacting protein 3-like protein (Bnip3L) interacts with bcl-2/Bcl-xL and induces apoptosis by altering...
7 KB (880 words) - 16:18, 13 October 2022
Adenovirus E1B protein usually refers to one of two proteins transcribed from the E1B gene of the adenovirus: a 55kDa protein and a 19kDa protein. These two...
8 KB (952 words) - 08:49, 29 December 2023
activation of caspase 3 and caspase 8, improved Bax/Bcl-2 ratio and down-regulation of p53.: 2388 Activated protein C also provides much protection of endothelial...
47 KB (5,346 words) - 02:39, 28 October 2024
IGFBP3 (redirect from Insulin-like growth factor binding protein 3)
IGF binding proteins (IGFBP-1 to IGFBP-6) that have highly conserved structures and bind the insulin-like growth factors IGF-1 and IGF-2 with high affinity...
39 KB (4,717 words) - 13:09, 2 June 2024
Fas ligand (redirect from Fas ligand protein)
protein Bid into its truncated form, tBid. BH-3 only members of the Bcl-2 family engage exclusively anti-apoptotic members of the family (Bcl-2, Bcl-xL)...
22 KB (2,547 words) - 08:19, 11 August 2024
activity) with: Bcl-2, Grb2, INSR, IGF1R, JAK1, JAK2, MAPK8, PIK3R1 PIK3R3, PTK2, PTPN11, PTPN1, and YWHAE. IRS-1, as a signalling adapter protein, is able to...
34 KB (4,304 words) - 07:20, 3 September 2024
facilitator Bcl-2-like protein 14 is a protein that in humans is encoded by the BCL2L14 gene. The protein encoded by this gene belongs to the BCL2 protein family...
5 KB (676 words) - 00:47, 2 December 2023