increases the local Ca2+ concentration around the RyR, by a factor of 10. Calcium sparks can either be evoked or spontaneous, as described below. Electrical...

activation of the L-type calcium channel, via an action potential, activates the RyR directly, causing calcium release (see calcium sparks for more details)...

relationships between T-tubules and calcium release began to be unravelled with the discovery of calcium sparks. While early work focussed on ventricular...

known as calcium-induced calcium release and gives rise to calcium sparks (Ca2+ sparks). The spatial and temporal summation of ~30,000 Ca2+ sparks gives...

into the cytoplasm, also known as calcium sparks. This increase in calcium within the cell then activates a sodium-calcium exchanger (NCX), which removes...

the detection of microscopic Ca2+ release events inside cells called "Calcium sparks". Whereas the salts of fluo-3 are unable to penetrate cells, loading...

well-studied example of these are the "calcium sparks" that are produced for a short period in the region around an open calcium channel. These are about 2 micrometres...

release of further sparks from neighbouring ryanodine receptors to create an organised rise of calcium throughout the cell known as a calcium transient. At...

Ryanodine receptors (RyR for short) form a class of intracellular calcium channels in various forms of excitable animal tissue like muscles and neurons...

regulator of sarcoplasmic release of stored calcium ions. It can reduce calcium sparks and thus arrhythmogenic calcium waves in the heart. While Flecainide therapy...

raise the magnitude of cell-averaged ICA-induced calcium transients and spontaneous calcium sparks in isolated heart cells. Furthermore, CASQ2 modulates...

This activation has been shown to result in either Ca2+ "sparks", highly localized calcium increases, or "waves", global Ca2+ increase that propagates...

of thousands of calcium sparks by the action potential causes a cell-wide increase in calcium giving rise to the upstroke of the calcium transient. The...

of breast cancer by the lab of Angela Brodie, and the discovery of calcium sparks as drivers of heart contraction by the lab of Jonathan Lederer. The...

Calcium imaging is a microscopy technique to optically measure the calcium (Ca2+) status of an isolated cell, tissue or medium. Calcium imaging takes...

and calcium and enhances the coupled openings of ryanodine receptors, which results in a higher frequency of calcium sparks and waves of calcium. It is...

pyrotechnic initiators – produce large amount of heat, flames, and/or hot sparks, used to ignite other compositions gas generators – produce large amount...

wrote and directed the action film Baby Driver (2017), the documentary The Sparks Brothers and the psychological horror film Last Night in Soho (both 2021)...

store calcium in the sarcoplasmic reticulum, even under the added stress of caffeine. Additionally, when treated with ParvE101Q, calcium sparks (spontaneous...

Removing impurities: The calcium carbonate in the limestone thermally decomposes to form calcium oxide. calcium carbonate → calcium oxide + carbon dioxide...

traces suggesting these tools were struck with the mineral pyrite to produce sparks around 50,000 years ago. At the Neolithic site of La Draga, researchers...

oxygen (O), nitrogen (N), phosphorus (P), potassium (K), sulfur (S), calcium (Ca), magnesium (Mg), iron (Fe), boron (B), manganese (Mn), copper (Cu)...

the process of cardiac calcium-induced calcium release, RYR2 is the major mediator for sarcoplasmic release of stored calcium ions. The channel is composed...

in which two compounds spontaneously ignite when mixed. The creation of sparks from metals is based on the pyrophoricity of small metal particles, and...

him. A series of injections and radiation designed to build a layer of calcium around the amygdala produces stunning results as Bernard's fear recedes...

of granular fusible flux consisting of lime, silica, manganese oxide, calcium fluoride, and other compounds. When molten, the flux becomes conductive...

coolant and/or slag flux. The flux often used in amateur compositions is calcium fluoride, as it reacts only minimally, has relatively low melting point...

dark B horizon; Presence of a caliche layer indicates the presence of calcium carbonates, which are present in alkaline conditions; Columnar structure...

with water at room temperature, though it reacts much more slowly than calcium, a similar group 2 metal. When submerged in water, hydrogen bubbles form...

bone and the enamel of mammalian teeth, whose strength is derived from calcium phosphate in the form of hydroxyapatite. It is also found in the exoskeleton...