Chiral analysis refers to the quantification of component enantiomers of racemic drug substances or pharmaceutical compounds. Other synonyms commonly...
63 KB (6,792 words) - 22:07, 2 December 2023
In chemistry, a molecule or ion is called chiral (/ˈkaɪrəl/) if it cannot be superposed on its mirror image by any combination of rotations, translations...
31 KB (3,668 words) - 05:48, 29 October 2024
Enantioselective synthesis (redirect from Chiral ligand)
reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecule and which produces the stereoisomeric...
41 KB (4,726 words) - 05:21, 27 May 2024
Chirality (/kaɪˈrælɪti/) is a property of asymmetry important in several branches of science. The word chirality is derived from the Greek χείρ (kheir)...
33 KB (3,806 words) - 17:14, 1 November 2024
chemists as chiral or handed molecules. Each twin is called an enantiomer. Drugs that exhibit handedness are referred to as chiral drugs. Chiral drugs that...
41 KB (4,547 words) - 13:45, 15 August 2024
Enantiomer (redirect from Chiral amplification)
specifying one of the two enantiomers (the absolute configuration) of a given chiral molecule: the R/S system is based on the geometry of the molecule; the (+)-...
24 KB (2,632 words) - 01:30, 4 November 2024
diastereomers can allow analysis. The use of chiral derivatizing agents has declined with the popularization of chiral HPLC. Besides analysis, chiral derivatization...
15 KB (1,818 words) - 23:00, 4 December 2023
Chirality timeline presents a timeline of landmark events that unfold the developments happened in the field of chirality. Many molecules come in two...
20 KB (1,365 words) - 14:46, 16 September 2024
Chromatography (section Chiral chromatography)
science, environment analysis, and hospitals. Affinity chromatography Aqueous normal-phase chromatography Binding selectivity Chiral analysis Chromatofocusing...
58 KB (7,255 words) - 14:50, 16 November 2024
Chiral inversion is the process of conversion of one enantiomer of a chiral molecule to its mirror-image version with no other change in the molecule...
27 KB (3,008 words) - 23:25, 11 November 2024
In theoretical physics, a chiral anomaly is the anomalous nonconservation of a chiral current. In everyday terms, it is equivalent to a sealed box that...
23 KB (3,271 words) - 19:11, 1 March 2024
is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule or salt. Racemic mixtures are rare in nature, but many compounds...
15 KB (1,826 words) - 10:08, 11 November 2024
A chiral switch is a chiral drug that has already approved as racemate but has been re-developed as a single enantiomer. The term chiral switching was...
25 KB (2,720 words) - 13:46, 15 August 2024
in the areas of natural products chemistry, protein chemistry, and chiral analysis by liquid chromatography. Bhushan began his education in his native...
5 KB (414 words) - 00:37, 12 November 2023
"Synthesis of TRIP and Analysis of Phosphate Salt Impurities". Synlett. 2010 (14): 2189–2192. doi:10.1055/s-0030-1258505. ISSN 0936-5214. "Chiral Phosphoric Acids"...
3 KB (207 words) - 17:17, 3 October 2024
chromatography with columns having a chiral stationary phase allows analyzing mixtures of enantiomers. The analysis of the enantiomeric distribution of...
24 KB (2,189 words) - 19:45, 21 July 2024
Methyl group (redirect from Chiral methyl)
(T), the methyl substituent becomes chiral. Methods exist to produce optically pure methyl compounds, e.g., chiral acetic acid (deuterotritoacetic acid...
12 KB (1,409 words) - 12:42, 4 October 2024
desired chirality thus simplifying the target. Directing a synthesis toward a desirable intermediate can greatly narrow the focus of analysis. This allows...
7 KB (749 words) - 02:51, 11 February 2024
Metamaterial (redirect from Chiral metamaterials)
cases are not chiral. Generally a chiral and/or bianisotropic electromagnetic response is a consequence of 3D geometrical chirality: 3D-chiral metamaterials...
93 KB (10,025 words) - 20:55, 10 October 2024
Spectroscopy (redirect from Spectroscopic analysis)
scattering and optical activity effects to reveal detailed information on chiral centers in molecules. Raman spectroscopy Saturated spectroscopy Scanning...
42 KB (4,615 words) - 16:25, 1 November 2024
Chiral column chromatography is a variant of column chromatography that is employed for the separation of chiral compounds, i.e. enantiomers, in mixtures...
21 KB (2,371 words) - 03:25, 10 March 2024
Homochirality (redirect from Chiral transmission)
Homochirality is a uniformity of chirality, or handedness. Objects are chiral when they cannot be superposed on their mirror images. For example, the left...
40 KB (5,098 words) - 21:14, 1 October 2024
enophile. In terms of the diastereoselection with respect to the newly created chiral centers, an endo preference has been qualitatively observed, but steric...
27 KB (3,345 words) - 05:39, 27 October 2024
QCD has spontaneous chiral symmetry breaking with the formation of a chiral condensate. Other phases of QCD may break the chiral flavour symmetries in...
24 KB (2,962 words) - 17:51, 18 October 2024
Accelerator Laboratory. He is renowned for his foundational work on the chiral anomaly (the Adler-Bardeen theorem), the Yang-Mills and gravitational anomalies...
18 KB (2,195 words) - 15:04, 5 September 2024
Spinor (redirect from Chiral fermion)
Fulton & Harris (1991). Jurgen Jost, "Riemannian Geometry and Geometric Analysis" (2002) Springer-Verlag Univeritext ISBN 3-540-42627-2. See chapter 1....
72 KB (9,924 words) - 07:46, 15 October 2024
asymmetric packing, which results in longer-range chiral order. In the smectic C* phase (an asterisk denotes a chiral phase), the molecules have positional ordering...
94 KB (11,498 words) - 14:35, 22 October 2024
with chiral compounds or in the presence of chiral catalysts, such as most enzymes. For this latter reason, the two enantiomers of most chiral compounds...
41 KB (5,523 words) - 06:03, 19 July 2024
Conformational isomerism (redirect from Conformational analysis)
version: (2006–) "gauche". doi:10.1351/goldbook.G02593 Conformational Analysis of Chiral Helical Perfluoroalkyl Chains by VCD Kenji Monde, Nobuaki Miura, Mai...
33 KB (3,846 words) - 18:11, 24 July 2024
followed by chiral chromatographic separation of the enantiomers. An early enantioselective route to atorvastatin made use of an ester chiral auxiliary...
100 KB (9,454 words) - 15:22, 12 November 2024