In pharmacology, clearance ( C l t o t {\displaystyle Cl_{tot}} ) is a pharmacokinetic parameter representing the efficiency of drug elimination. This...

speed at which a constituent of urine passes through the kidneys Clearance (pharmacology), the rate at which a substance is removed or cleared from the...

produced by the body, whereas inulin has to be intravenously infused. Clearance (pharmacology) Kt/V Rudolfs K. Zalups; Lawrence H. Lash (1996). Methods in Renal...

points in time and the trapezoidal rule is used to estimate AUC. In pharmacology, the area under the plot of plasma concentration of a drug versus time...

In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation....

In pharmacology, the elimination or excretion of a drug is understood to be any one of a number of processes by which a drug is eliminated (that is, cleared...

discussion 1193–7. PMID 17716385. Rubin, Bruce K. (2006). "The pharmacologic approach to airway clearance: Mucoactive agents". Paediatric Respiratory Reviews. 7...

In pharmacology, augmented renal clearance (ARC) is a phenomenon where certain critically ill patients may display increased clearance of a medication...

or central vein. In pharmacology, the route of drug administration is important because it affects drug metabolism, drug clearance, and thus dosage. The...

IC50 is commonly used as a measure of antagonist drug potency in pharmacological research. IC50 is comparable to other measures of potency, such as...

The pharmacology of ethanol involves both pharmacodynamics (how it affects the body) and pharmacokinetics (how the body processes it). In the body, ethanol...

contribution of CYP3A to amitriptyline clearance in humans: in vitro and in vivo studies". Journal of Clinical Pharmacology. 41 (10): 1043–1054. doi:10.1177/00912700122012634...

mainly excreted by tubular secretion in the kidney. In kidney impairment, clearance is reduced, increasing the risk of adverse effects. Lower initial doses...

fast enough to sample dynamics of neurotransmitter release and clearance. Pharmacological action of dopaminergic drugs such as D1 and D2 receptors agonists...

Chemically, PCP is a member of the arylcyclohexylamine class, and pharmacologically, it is a dissociative anesthetic. PCP works primarily as an NMDA receptor...

In the field of drug discovery, reverse pharmacology also known as target-based drug discovery (TDD), a hypothesis is first made that modulation of the...

hepatic first-pass effect. Clearance of olanzapine appears to vary by sex; women have roughly 25% lower clearance than men. Clearance of olanzapine also varies...

The pharmacology of selegiline pertains to the pharmacodynamic and pharmacokinetic properties of the antiparkinsonian and antidepressant selegiline (L-deprenyl)...

approximately 35%, the volume of distribution is 3.5 L/kg and the total clearance is approximately 15 L/h. Bisoprolol is eliminated from the body in two...

can increase chlorpromazine clearance significantly. Tricyclic antidepressants (TCAs) can decrease chlorpromazine clearance and hence increase chlorpromazine...

information) Riviere JE, Papich MG (2017). "Maropitant". Veterinary Pharmacology and Therapeutics. John Wiley & Sons. p. 2828. ISBN 978-1-118-85588-1...

(October 2014). "Lithium: a review of pharmacology, clinical uses, and toxicity". European Journal of Pharmacology. 740 (740): 464–473. doi:10.1016/j.ejphar...

In pharmacology, the volume of distribution (VD, also known as apparent volume of distribution, literally, volume of dilution) is the theoretical volume...

In the field of drug discovery, classical pharmacology, also known as forward pharmacology, or phenotypic drug discovery (PDD), relies on phenotypic screening...

ISBN 978-0-85711-338-2. Rang HP, Dale MM, Ritter JM, Flower RJ. Rang and Dale's Pharmacology. Tariq S, Aronow WS (December 2015). "Use of Inotropic Agents in Treatment...

The elimination half-life of cyclobenzaprine is 18 hours and it has a clearance of 0.7 L/min. Cyclobenzaprine is a tricyclic compound of the dibenzocycloheptene...

to treat chronic obstructive pulmonary disease (COPD) and asthma. Its pharmacology is similar to other methylxanthine drugs (e.g., theobromine and caffeine)...

In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body. Routes...

Drug Administration. She was previously director of the department of pharmacology and molecular sciences at Johns Hopkins University School of Medicine...

reticulum, and its expression is induced by glucocorticoids and some pharmacological agents. Cytochrome P450 enzymes metabolize approximately 60% of prescribed...