• Thumbnail for Complementarity-determining region
    Complementarity-determining regions (CDRs) are polypeptide segments of the variable chains in immunoglobulins (antibodies) and T cell receptors, generated...
    8 KB (934 words) - 21:07, 3 July 2024
  • Look up complementarity or complementary in Wiktionary, the free dictionary. Complementarity may refer to: Complementarity (molecular biology), a property...
    1 KB (179 words) - 03:54, 8 February 2017
  • their expectations and their reality. Complementarity-determining region, one of six hypervariable loops which determine the antigen specificity of a given...
    5 KB (706 words) - 20:52, 22 February 2024
  • human variant, despite the non-human origin of some of its complementarity-determining region (CDR) segments responsible for the ability of the antibody...
    14 KB (1,787 words) - 23:05, 9 January 2024
  • Thumbnail for Omalizumab
    Omalizumab Omalizumab structure: (A) murine complementarity-determining region and (B) IgG1κ human framework Monoclonal antibody Type Whole antibody Source...
    47 KB (4,909 words) - 05:35, 5 August 2024
  • Thumbnail for Fragment antigen-binding region
    the paratope (the antigen-binding site), comprising a set of complementarity-determining regions, at the amino terminal end of the monomer. Each arm of...
    6 KB (688 words) - 06:34, 7 July 2024
  • Thumbnail for Paratope
    antibody's heavy and light chains. Each paratope is made up of six complementarity-determining regions - three from each of the light and heavy chains - that...
    4 KB (457 words) - 23:44, 30 June 2023
  • was derived from a mouse antibody which was humanized via Complementarity Determining Region (CDR) grafting. Its serum half-life is 25.4 days. Other PD-1...
    37 KB (3,213 words) - 06:55, 8 August 2024
  • study identified the preferential presence of the TCR-V-b and complementarity-determining region 3 in T-cell receptors found on the T cells in the blisters...
    38 KB (4,291 words) - 02:57, 28 November 2023
  • three, several disulfide bonds in unusual positions, and the complementarity-determining region 3 (CDR3) forms an extended loop covering the site which binds...
    8 KB (871 words) - 16:19, 20 July 2024
  • study identified the preferential presence of the TCR-V-b and complementarity-determining region 3 in T-cell receptors found on the T cells in the blisters...
    56 KB (5,843 words) - 02:52, 19 June 2024
  • CDR1 can refer to Complementarity-determining region 1 on antibodies CDR1 (gene), cerebellar degeneration-related protein 1 This disambiguation page lists...
    188 bytes (54 words) - 11:09, 30 October 2023
  • Thumbnail for Single-domain antibody
    less lipophilic and more soluble in water, owing to their complementarity-determining region 3 (CDR3), which forms an extended loop (coloured orange in...
    35 KB (3,898 words) - 14:53, 18 May 2024
  • Thumbnail for Complementarity (molecular biology)
    biology, complementarity describes a relationship between two structures each following the lock-and-key principle. In nature complementarity is the base...
    23 KB (2,586 words) - 20:09, 27 March 2024
  • identified the preferential presence of the TCR-V-b and complementarity-determining region 3 in T-cell receptors found on the T cells in the blisters...
    35 KB (4,082 words) - 11:48, 2 July 2024
  • CDR2 can refer to Complementarity-determining region 2 on antibodies CDR2 (gene), cerebellar degeneration-related protein 2, a protein expressed by ovarian...
    319 bytes (76 words) - 09:22, 21 January 2020
  • Thumbnail for Framework region
    framework regions are responsible for acting as a scaffold for the complementarity determining regions (CDR), also referred to as hypervariable regions, of...
    9 KB (1,075 words) - 18:36, 5 August 2024
  • Thumbnail for Idiotype
    variable region. The variable region of antigen receptors of T cells (TCRs) and B cells (immunoglobulins) contain complementarity-determining regions (CDRs)...
    3 KB (312 words) - 16:27, 29 December 2021
  • is that each TCR is unique and recognizes a specific antigen Complementarity determining regions (CDRs) are a part of the TCR and play an essential role...
    22 KB (2,554 words) - 14:34, 22 July 2024
  • Thumbnail for Antibody
    surface of the antibody. These loops are referred to as the complementarity-determining regions (CDRs), since their shape complements that of an antigen...
    118 KB (13,287 words) - 12:29, 5 August 2024
  • identified a particularly variable segment, now known as complementarity-determining region 3. Her research also pointed to evidence that at least two...
    5 KB (432 words) - 07:22, 7 May 2024
  • Neutralisation Regions Paratope Complementarity-determining region (CDRs) Hypervariable region Framework region Fab Region Fc Region Polyclonal B cell response...
    38 KB (2,656 words) - 12:11, 30 October 2023
  • Thumbnail for Polymeric immunoglobulin receptor
    receptor/ligand interactions. Evidence for the involvement of multiple complementarity determining region (CDR)-like loops in receptor domain I". The Journal of Biological...
    20 KB (2,421 words) - 03:40, 5 February 2024
  • factor 1 receptor Colony-stimulating factor Common gamma chain Complementarity-determining region Computational immunology Contact immunity CpG Oligodeoxynucleotide...
    13 KB (1,237 words) - 01:24, 15 January 2024
  • cells. Yang X, Zhao Q, Zhu L, Zhang W (May 2013). "The three complementarity-determining region-like loops in the second extracellular domain of human Fc...
    2 KB (152 words) - 03:37, 15 July 2024
  • Thumbnail for International Criminal Court
    principle of complementarity, and (3) the investigation serves the interests of justice.: article 53(1)  The principle of complementarity means the Court...
    216 KB (21,944 words) - 18:17, 10 August 2024
  • distance to its antigen. They named "HV4" and "LV4", non-complementarity-determining region (CDR) loops that are structurally close to the antigen and...
    10 KB (1,279 words) - 16:05, 28 March 2024
  • Neutralization of HIV-1 and Hydrophobicity of Its Heavy Chain Third Complementarity-Determining Region". Journal of Virology. 84 (6): 2955–2962. doi:10.1128/JVI...
    13 KB (1,646 words) - 06:28, 27 November 2023
  • concentrated in hypervariable regions. These regions correspond to the complementarity-determining regions; the sites involved in antigen recognition on the immunoglobulin...
    9 KB (1,013 words) - 09:10, 9 January 2024
  • Thumbnail for Black hole
    black hole complementarity. In 2012, the "firewall paradox" was introduced with the goal of demonstrating that black hole complementarity fails to solve...
    164 KB (18,501 words) - 04:51, 26 July 2024