Cubilin is a protein that in humans is encoded by the CUBN gene. Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role...

ileum. This receptor is composed of two proteins, amnionless (AMN), and cubilin. A defect in either of these protein components can cause this syndrome...

vitamin B12. Cubam is essentially composed of amnionless (AMN), and cubilin. Cubilin is essential as a cell receptor recognizing the "vitamin B12-intrinsic...

B12-IF complexes travel to the ileum portion of the small intestine where cubilin receptors enable assimilation and circulation of B12-IF complexes in the...

syndrome, a B12-deficiency caused by mutations in CUBN that codes for cubilin the cobalamin receptor. Vitamin B12 deficiency is also prevalent in patients...

EI, Nielsen R, Birn H (Feb 2013). "From bowel to kidneys: the role of cubilin in physiology and disease". (review). Nephrology, Dialysis, Transplantation...

that in humans is encoded by the AMN gene. A complex of amnionless and cubilin forms the cubam receptor. The protein encoded by this gene is a type I...

presence of food in the stomach. IF delivers the vitamin to receptor proteins cubilin and amnionless, which together form the cubam receptor in the distal ileum...

the small intestine, and has on its surface specialized receptors called cubilin receptors, that identify the B12–IF complexes and take them up into the...

Willnow TE, Christensen EI, Moestrup SK (October 2001). "Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin...

gp18/gp30, and some other proteins like osteonectin, hnRNPs, calreticulin, cubilin, and megalin. Bovine serum albumin Serum albumin GRCh38: Ensembl release...

or transcytosis. LRP2/megalin can also form complexes with CUBAM, the cubilin and amnionless complex. Those complexes are able to reabsorb several molecules...

Navani, Sanjay (2017-01-04). "A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma". BMC Cancer...

the hemoglobin can be reabsorbed in the proximal tubules through binding cubilin and megalin, in doing so it competes with albumin, so the build up of hemoglobin...

formation/function of the endocytic complex that also involves megalin and cubilin/amnionless receptors, the sodium-hydrogen antiporter 3 (NHE3), and the...

association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1)". Birth Defects...

2003). "Rat enterocytes secrete SLPs containing alkaline phosphatase and cubilin in response to corn oil feeding". American Journal of Physiology. Gastrointestinal...