A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a...
31 KB (3,853 words) - 11:23, 9 January 2025
growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages and neutrophils. CD4+ cells are mature Th cells that...
54 KB (6,612 words) - 12:14, 31 January 2025
"killer T cells", are cytotoxic – this means that they are able to directly kill virus-infected cells, as well as cancer cells. CD8+ T cells are also...
71 KB (9,063 words) - 08:00, 15 January 2025
these cells: CD4+ TH1 cells CD8+ cytotoxic T cells (Tc1) T-Bet+ interferon gamma producing group 1 ILCs(ILC1 and Natural killer cells) CD4+ TH1 Cells It...
14 KB (1,377 words) - 16:49, 20 November 2024
Natural killer cells, also known as NK cells, are a type of cytotoxic lymphocyte critical to the innate immune system. They are a kind of large granular...
75 KB (9,227 words) - 23:32, 16 October 2024
and T cells. Antigen-presenting cells are vital for effective adaptive immune response, as the functioning of both cytotoxic and helper T cells is dependent...
16 KB (2,128 words) - 09:55, 4 March 2024
Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are toxic metals, toxic chemicals, microbe neurotoxins, radiation particles...
10 KB (1,379 words) - 06:49, 2 December 2024
antigen on a cell's surface, T cells bind to it and become activated, then proceed to proliferate and become cytotoxic. CAR T cells destroy cells through several...
89 KB (9,201 words) - 14:01, 23 January 2025
blood T cells. Natural killer T cells should neither be confused with natural killer cells nor killer T cells (cytotoxic T cells). The term "NK T cells" was...
14 KB (1,648 words) - 09:58, 18 July 2023
the cytotoxic T cells (CD8-positive) subset, similar populations appear to exist for both the helper T cells (CD4-positive) and the cytotoxic T cells. Primary...
32 KB (3,781 words) - 12:49, 26 April 2024
Gamma delta T cells (γδ T cells) are T cells that have a γδ T-cell receptor (TCR) on their surface. Most T cells are αβ (alpha beta) T cells with TCR composed...
35 KB (4,472 words) - 00:20, 13 June 2024
cytoskeletal remodeling resulting in T-cell activation. Active T cells secrete cytokines, undergo rapid proliferation, have cytotoxic activity and differentiate...
43 KB (5,372 words) - 09:17, 17 December 2024
are the naive forms of helper T cells (CD4+) and cytotoxic T cells (CD8+). Naive T cells, unlike activated or memory T cells, have not encountered its cognate...
9 KB (1,128 words) - 19:36, 21 January 2025
DNA vaccine (section Cytotoxic T-cell responses)
helper and cytotoxic T-cells can control viral infections by secreting interferons. Cytotoxic T cells usually kill virally infected cells. However, they...
77 KB (8,378 words) - 02:14, 15 January 2025
Intravascular lymphomas (redirect from Angiotropic large cell lymphoma)
lymphoma (IVTL) in which the neoplastic cells are primarily, if not exclusively, a type of t-cell termed cytotoxic T-cells. Because of their similarities and...
38 KB (4,735 words) - 06:59, 29 April 2024
transformation of either one of two types of lymphocytes, NK cells or a T cell variant termed cytotoxic T cells, that are infected with the Epstein–Barr virus (EBV)...
46 KB (5,490 words) - 18:03, 8 December 2024
Lymphoid cells (lymphocytes) include T cells (subdivided into helper T cells, memory T cells, cytotoxic T cells), B cells (subdivided into plasma cells and...
32 KB (3,218 words) - 10:47, 8 January 2025
Epstein–Barr virus–associated lymphoproliferative diseases (section EBV+ NK/T cell lymphoproliferative diseases)
delta T cells (γδ T cells), cytotoxic T cells (CTL), helper T cells (Th cells), and follicular B helper T cells (TFH cells). The means by which EBV establishes...
139 KB (16,974 words) - 02:10, 1 February 2025
Granzyme B (redirect from Cytotoxic cell proteinase-1)
found in the granules of natural killer cells (NK cells) and cytotoxic T cells. It is secreted by these cells along with the pore forming protein perforin...
17 KB (2,040 words) - 15:35, 22 October 2024
Original antigenic sin (section In cytotoxic T cells)
immunological imprinting. A similar phenomenon has been described in cytotoxic T cells (CTL). It has been demonstrated that during a second infection by...
12 KB (1,251 words) - 06:08, 30 October 2024
Cross-presentation (section Cross-presenting cells)
antigen-presenting cells (mostly dendritic cells) to take up, process and present extracellular antigens with MHC class I molecules to CD8 T cells (cytotoxic T cells)....
18 KB (2,159 words) - 21:24, 20 November 2024
Antibody-dependent cellular cytotoxicity (ADCC), also referred to as antibody-dependent cell-mediated cytotoxicity, is a mechanism of cell-mediated immune defense...
13 KB (1,661 words) - 22:18, 9 December 2023
between the epithelial cells that line these organs' lumens. These IEL often exhibit natural killer and cytotoxic T-cell cell activation markers, contain...
47 KB (5,544 words) - 09:11, 19 March 2024
II IFN is primarily secreted by CD4+ T helper 1 (Th1) cells, natural killer (NK) cells, and CD8+ cytotoxic T cells. The expression of type II IFN is upregulated...
56 KB (6,483 words) - 16:47, 27 December 2024
The regulatory T cells (Tregs /ˈtiːrɛɡ/ or Treg cells), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune...
79 KB (9,482 words) - 16:04, 19 January 2025
large granular lymphocyte leukemia is characterized by involvement of cytotoxic-T cells). In a study based in the US, the average age of diagnosis was 66...
14 KB (1,539 words) - 07:57, 14 October 2024
Lymphocyte (redirect from Lymphoid Cell)
cell (leukocyte) in the immune system of most vertebrates. Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for...
23 KB (2,445 words) - 12:25, 31 December 2024
Cytotoxic T-lymphocyte associated protein 4, (CTLA-4) also known as CD152 (cluster of differentiation 152), is a protein receptor that functions as an...
30 KB (3,464 words) - 22:51, 24 May 2024
MHC class I attract T-lymphocytes called killer T-cells (also referred to as CD8-positive or cytotoxic T-cells) that destroy cells. Some new work has proposed...
51 KB (5,942 words) - 07:28, 11 November 2024
Degranulation (category Cell biology)
antimicrobial, cytotoxic, or other molecules from secretory vesicles called granules found inside some cells. It is used by several different cells involved...
6 KB (635 words) - 08:51, 28 July 2024