disadvantages of deuterated drugs. A number of publications have discussed aspects of intellectual property of deuterated versions of drugs. Deutetrabenazine...
15 KB (1,369 words) - 20:29, 22 July 2024
Deuterated etifoxine (developmental code name GRX-917) is a deuterated drug which is under development for the treatment of anxiety disorders and mood...
7 KB (537 words) - 06:15, 18 January 2024
Deutetrabenazine (category Deuterated compounds)
S2CID 205269152. "FDA Determines that Deuterated Compounds are NCEs and Different Orphan Drugs Versus Non-deuterated Versions". FDA Law Blog. 16 July 2017...
9 KB (652 words) - 11:11, 31 July 2024
company Retrotope pioneered the development a source of deuterated omega-6 fatty acid di-deuterated linoleic acid ethyl ester (RT001) as a food additive...
5 KB (519 words) - 19:40, 19 January 2024
used and abused psychoactive drugs in the world and falls under the depressant category. The term "Alcohol and Other Drugs" (AOD) emphasizes this inclusion...
236 KB (24,256 words) - 05:42, 25 August 2024
Deucravacitinib (category Deuterated compounds)
PMID 34471993. Mullard A (September 2022). "First de novo deuterated drug poised for approval". Nature Reviews. Drug Discovery. 21 (9): 623–625. doi:10.1038/d41573-022-00139-6...
12 KB (697 words) - 09:25, 1 July 2024
Deuremidevir (category Deuterated compounds)
analogue antiviral drug. It is administrated through oral tablets, which contain the hydrobromide salt of this drug. The drug is a deuterated tri-isobutyrate...
5 KB (481 words) - 07:29, 14 August 2024
Deulinoleate ethyl (redirect from Di-deuterated linoleic acid ethyl ester)
Deulinoleate ethyl (also known as di-deuterated ethyl linoleate, di-deuterated linoleic acid ethyl ester, 11,11-d2-ethyl linoleate, or ethyl 11,11-d2-linoleate)...
9 KB (802 words) - 05:31, 28 May 2024
cancer. Examples of non-radioactive medical isotopes are: Deuterium in deuterated drugs Carbon-13 used in liver function and metabolic tests Organisation for...
2 KB (217 words) - 16:32, 14 May 2024
spectroscopy, deuterated solvents for proton NMR spectroscopy, in heavy water nuclear reactors (as a coolant and moderator) and in deuterated drugs. Karl-Hermann...
7 KB (890 words) - 03:23, 5 June 2024
Nonbenzodiazepine (redirect from Z-drug)
colloquially as Z-drugs (as many of their names begin with the letter "z"), are a class of psychoactive, depressant, sedative, hypnotic, anxiolytic drugs that are...
30 KB (3,208 words) - 00:02, 5 August 2024
Jaktinib (category Deuterated compounds)
janus kinase inhibitor under development for myelofibrosis. It is a deuterated-drug analog of momelotinib. Zhang, Yi; Zhou, Hu; Jiang, Zhongxing; Wu, Dengshu;...
4 KB (194 words) - 08:00, 31 May 2024
Deudomperidone (redirect from Deuterated domperidone)
Deudomperidone (developmental code name CIN-102; also known as deuterated domperidone) is a dopamine antagonist medication which is under development in...
4 KB (171 words) - 06:40, 6 August 2023
Pharma is evaluating the potential of deuterated vitamin A as the drug ALK-001. The hope is that the deuterated vitamin A will reduce the build-up of...
24 KB (2,922 words) - 04:28, 19 August 2024
Reinforced lipids (category Deuterated compounds)
2020). "Site-specifically deuterated essential lipids as new drugs against neuronal, retinal and vascular degeneration". Drug Discovery Today. 25 (8):...
13 KB (1,312 words) - 06:19, 13 August 2024
Alprazolam (category Drugs with non-standard legal status)
increase drowsiness, especially in those unaccustomed to the drug's effects. Sedative drugs, including alprazolam, have been associated with an increased...
89 KB (8,353 words) - 11:27, 16 August 2024
Fluoxetine (redirect from Reconcile (drug))
Reuptake Inhibitors and Cytochrome P-450 Mediated Drug-Drug Interactions: An Update". Current Drug Metabolism. 3 (1): 13–37. doi:10.2174/1389200023338017...
119 KB (11,703 words) - 11:06, 16 August 2024
President, CEO, Cofounder of DeuteRx which has developed PXL065 a Deuterated drug. Awarded Women to Watch (2013). She is a pioneer of Combinatorial Chemistry...
23 KB (2,473 words) - 00:14, 31 July 2024
List of investigational antidepressants (category Drug-related lists)
[27] Deudextromethorphan/quinidine (AVP-786; CTP-786; d-DM/Q; d6-DM/Q; deuterated dextromethorphan/ultra-low-dose quinidine) – sigma σ1 receptor agonist...
100 KB (8,159 words) - 01:51, 24 August 2024
Flunitrazepam (category Drug culture)
or "floonies", is widely known for its use as a date rape drug. In countries where this drug is used, it is used for treatment of severe cases of sleeping...
38 KB (3,723 words) - 15:02, 16 August 2024
Clonazepam (category Drugs with non-standard legal status)
prescriptions. In many areas of the world, it is commonly used as a recreational drug. Clonazepam is prescribed for short-term management of epilepsy, anxiety...
78 KB (7,587 words) - 00:50, 19 August 2024
Methaqualone (redirect from Lemmon (drug))
others, which contained 300 mg of methaqualone, and sold as a combination drug under the brand name Mandrax, which contained 250 mg methaqualone and 25 mg...
25 KB (2,519 words) - 19:59, 10 August 2024
4-D (psychedelic) (category Deuterated compounds)
lesser-known recreational psychedelic drug. It is one of the few drugs that bears deuterium. It is a deuterated analog of mescaline. It may be prepared...
2 KB (140 words) - 10:04, 22 November 2023
Isotope effect on lipid peroxidation (section Drugs using the isotope effect on lipid peroxidation (clinical research))
context in drug development, modulating drug properties in a favorable/patient-friendly way (deuterated drugs). Small molecules used as drugs are recognized...
15 KB (1,728 words) - 12:41, 24 June 2024
Pentobarbital (category Drugs with non-standard legal status)
insomnia but has been largely replaced by the benzodiazepine family of drugs. In high doses, pentobarbital causes death by respiratory arrest. It is...
21 KB (1,931 words) - 05:53, 24 August 2024
Tebideutorexant (category Deuterated compounds)
reported for treatment of panic disorder and other anxiety disorders. The drug was originated and developed by Janssen Pharmaceuticals. List of investigational...
5 KB (272 words) - 19:54, 15 August 2024
Etifoxine (category Drugs with non-standard legal status)
but development was discontinued. A deuterated form of etifoxine with improved pharmacokinetics known as deuterated etifoxine (GRX-917) is under development...
37 KB (3,481 words) - 19:07, 22 June 2024
Corvalol (category Combination drugs)
Corvalol was developed in the USSR in 1960 as an analogue of the German drug Valocordin, and is therefore similar in composition and action. Corvalol...
11 KB (1,220 words) - 12:34, 14 July 2024
Benzodiazepine (redirect from Benzodiazepine drug)
(BZD, BDZ, BZs), colloquially called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine...
159 KB (16,654 words) - 05:27, 30 July 2024