In organic chemistry, diazirines are a class of organic molecules consisting of a carbon bound to two nitrogen atoms, which are double-bonded to each other...
25 KB (2,585 words) - 19:20, 25 October 2024
photoreactive diazirine analogs to leucine and methionine, which are incorporated into proteins. Upon exposure to ultraviolet light, the diazirines are activated...
18 KB (1,797 words) - 09:34, 27 July 2024
Graham reaction (category Diazirines)
Graham reaction is an oxidation reaction that converts an amidine into a diazirine using a hypohalite reagent. The halide of the hypohalite oxidant, or another...
2 KB (204 words) - 06:59, 19 May 2021
produced from an extrusion reaction with a large free energy change. Diazirines and epoxides photolyze with a tremendous release in ring strain to carbenes...
22 KB (2,401 words) - 05:50, 13 August 2024
CH2N2 may refer to: Cyanamide, an organic compound Diazirine, class of organic molecules with a cyclopropene-like ring, 3H-diazirene Diazomethane, chemical...
516 bytes (91 words) - 16:07, 16 December 2019
vitro. Photo-reactive amino acid analogs in common use are photoreactive diazirine analogs to leucine and methionine, and para-benzoylphenylalanine. Upon...
4 KB (506 words) - 02:56, 1 April 2024
heteroatoms Heteroatoms Saturated Unsaturated 2 × Nitrogen Diaziridine Diazirine Nitrogen + Oxygen Oxaziridine Oxazirine Nitrogen + Sulfur Thiaziridine...
20 KB (1,019 words) - 22:20, 25 October 2024
such as ketene (ethenone) (CH 2=CO), diazomethane (linear CH 2=N 2), diazirine (cyclic [-CH 2-N=N-]) and diiodomethane (I-CH 2-I). The decomposition...
15 KB (1,504 words) - 15:19, 25 October 2024
mammalian GABAA receptors has been identified by photolabeling using a diazirine derivative. Additionally, it was shown that the hyaluronan polymer present...
56 KB (5,566 words) - 04:53, 25 September 2024
L-Photo-leucine (category Diazirines)
l-Leucine amino acid. l-photo-leucine is characterized by the presence of a diazirine ring linked to the R radical of the original amino acid. This cyclopropene...
14 KB (1,791 words) - 09:19, 24 July 2024
TDBzcholine (category Diazirines)
TDBzcholine is a diazirine analog of acetylcholine that can be used to label the nicotinic acetylcholine receptor. TDBzcholine is able to bind to the...
2 KB (85 words) - 18:11, 19 August 2022
stable but still isolable isomers of diazomethane include the cyclic 3H-diazirine and isocyanoamine (isodiazomethane). In addition, the parent nitrilimine...
18 KB (1,648 words) - 07:02, 27 July 2024
functional groups are replaced with a photoreactive group, such as an azide, a diazirine or a benzophenone. Photoaffinity labeling Photoaffinity labeling, Gold...
3 KB (292 words) - 12:27, 5 June 2023
leverages the photonic energy of iridium-based photocatalysts to activate diazirine probes that can tag proximal proteins within a tight radius of about four...
18 KB (2,018 words) - 01:47, 11 April 2024
group of isomeric compounds with only few similar properties are the diazirines, where the carbon and two nitrogens are linked as a ring. Four resonance...
13 KB (1,439 words) - 01:23, 17 July 2024
L-Photo-methionine (category Diazirines)
previous synthesis had worked, photo-methionine is photo-reactive due to the diazirine ring. Once this ring has become exposed to UV light, nitrogen leaves as...
21 KB (2,542 words) - 09:55, 8 November 2023
mammalian GABAA receptors has been identified by photolabeling using a diazirine derivative. Strong activation of tonic GABAA receptor conductance by clinical...
63 KB (6,813 words) - 14:04, 5 October 2024
facilitate a better understanding of biological mechanisms. RNP-MaP uses NHS-diazirine (SDA), a hetero-bifunctional crosslinker, to freeze RNA-bound proteins...
15 KB (1,854 words) - 12:16, 22 February 2024
photoreactive diazirine analogs to leucine and methionine, which are incorporated into proteins. Upon exposure to ultraviolet light, the diazirines are activated...
35 KB (4,515 words) - 07:57, 6 August 2024
diaziridines are often directly oxidized (I2/NEt3) to the more stable diazirines. They can undergo ring expansion reaction with electrophilic reagents...
2 KB (149 words) - 16:47, 16 July 2021
O-GlcNAcylated proteins. The N-acetyl group may be elongated to incorporate a diazirine moiety. Treatment of cells with peracetylated, phosphate-protected...
108 KB (12,376 words) - 16:09, 30 March 2024
Dailey et al. reported that the photolysis of 3-bromo-3-(trifluoromethyl)diazirines in an argon matrix could afford bromo(trifluoromethyl)carbene....
12 KB (1,355 words) - 12:26, 23 September 2024
cyclohexanone) diaziridines, which can easily be oxidized to the more stable diazirines. The reaction also provides substituted aziridines from simple aldehydes...
17 KB (1,606 words) - 08:39, 27 August 2024
synthesis, iterative cross-coupling, and accessing reactive, unstable diazirines.[citation needed] It is designed to perform these reactions in a single...
7 KB (744 words) - 04:20, 19 September 2024
fragmentation. A closely related fragmentation has been reported, employing diazirine derivatives of cyclic α,β-epoxyketones. Grob fragmentation Wharton reaction...
8 KB (798 words) - 06:51, 20 March 2021
2001). "Interactions between 3-(trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine and tetracaine, phencyclidine, or histrionicotoxin in the Torpedo species...
11 KB (1,411 words) - 23:21, 26 October 2023
Kaiser, Markus; Bayer, Peter (2020). "Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in...
17 KB (1,505 words) - 15:21, 26 April 2024
Kaiser, Markus; Bayer, Peter (2020). "Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in...
6 KB (508 words) - 00:30, 3 December 2023
Methyldiazinol (category Diazirines)
orally, among the highest noted. Church RF, Kende AS, Weiss MJ (1965). "Diazirines. I. Some Observations on the Scope of the Ammonia-Hydroxylamine-O-sulfonic...
4 KB (214 words) - 17:46, 11 November 2023