for elastase: Some bacteria (including Pseudomonas aeruginosa) also produce elastase. In bacteria, elastase is considered a virulence factor. Elastase breaks...
6 KB (477 words) - 23:45, 3 February 2024
Neutrophil elastase (EC 3.4.21.37, leukocyte elastase, ELANE, ELA2, elastase 2, neutrophil, elaszym, serine elastase, subtype human leukocyte elastase (HLE))...
9 KB (1,111 words) - 20:35, 7 May 2024
Pancreatic elastase is a form of elastase that is produced in the acinar cells of the pancreas, initially produced as an inactive zymogen and later activated...
15 KB (1,794 words) - 01:00, 18 July 2024
CELA3B (redirect from Fecal elastase)
Chymotrypsin-like elastase family member 3B also known as elastase-3B, protease E, or fecal elastase is an enzyme that in humans is encoded by the CELA3B...
7 KB (889 words) - 07:25, 6 January 2024
only binds to neutrophil elastase from inflammatory cells but also to elastase on the cell surface. In this latter role, elastase acts as a signaling molecule...
33 KB (3,383 words) - 08:00, 21 August 2024
'moderate' EPI is when fecal elastase levels are <200 ug/g, whereas 'severe' EPI is considered to be when fecal elastase levels is <100 ug/g. The exocrine...
29 KB (3,058 words) - 14:48, 20 September 2024
environmental dust. The underlying mechanism involves unblocked neutrophil elastase and buildup of abnormal A1AT in the liver. It is autosomal co-dominant...
27 KB (2,883 words) - 23:15, 10 September 2024
Serine protease (section Elastase-like)
their substrate specificity as either trypsin-like, chymotrypsin-like or elastase-like. Trypsin-like proteases cleave peptide bonds following a positively...
22 KB (2,343 words) - 20:13, 29 August 2024
parasites. In alpha 1-antitrypsin deficiency, the important neutrophil elastase is not adequately inhibited by alpha 1-antitrypsin, leading to excessive...
53 KB (5,693 words) - 06:53, 24 September 2024
Pancreatic elastase II (EC 3.4.21.71, pancreatic elastase 2) is an enzyme. This enzyme catalyses the following chemical reaction Preferential cleavage:...
1 KB (149 words) - 15:16, 26 August 2023
Macrophage elastase (EC 3.4.24.65, metalloelastase, human macrophage metalloelastase (HME), MMP-12) is an enzyme. This enzyme catalyses the following chemical...
2 KB (200 words) - 14:49, 26 August 2023
Elaszym (redirect from Serine elastase)
Elaszym may refer to one of two enzymes: Pancreatic elastase Neutrophil elastase This disambiguation page lists articles associated with the title Elaszym...
109 bytes (43 words) - 09:59, 28 December 2019
Pseudolysin (redirect from Pseudomonas elastase)
Pseudolysin (EC 3.4.24.26, Pseudomonas elastase, Pseudomonas aeruginosa neutral metalloproteinase) is an enzyme. This enzyme catalyses the following chemical...
2 KB (230 words) - 15:36, 26 August 2023
acid, it forms hyaluronan. GlcNAc has been reported to be an inhibitor of elastase release from human polymorphonuclear leukocytes (range 8–17% inhibition)...
8 KB (570 words) - 21:44, 8 May 2024
SERPINB1 (redirect from Leukocyte elastase inhibitor)
Leukocyte elastase inhibitor (LEI) also known as serpin B1 is a protein that in humans is encoded by the SERPINB1 gene. It is a member of the clade B serpins...
9 KB (1,148 words) - 17:04, 26 July 2024
aflatoxin damaged liver cells and bile duct cells are removed by neutrophil elastase and by involvement of immune system mediators such as CCL-2 or MCP-1, tumor...
25 KB (2,730 words) - 01:09, 29 September 2024
Azurophils may contain myeloperoxidase, phospholipase A2, acid hydrolases, elastase, defensins, neutral serine proteases, bactericidal permeability-increasing...
3 KB (216 words) - 19:28, 5 December 2023
protein that in humans is encoded by the PI3 gene. This gene encodes an elastase-specific protease inhibitor, which contains a WAP-type four-disulfide core...
9 KB (1,033 words) - 02:02, 15 August 2024
Each family may contain many hundreds of related proteases (e.g. trypsin, elastase, thrombin and streptogrisin within the S1 family). Currently more than...
26 KB (2,799 words) - 15:02, 30 June 2024
Littré. Smegma contains cathepsin B, lysozymes, chymotrypsin, neutrophil elastase and cytokines, which aid the immune system. According to Wright, the production...
12 KB (1,214 words) - 20:18, 24 September 2024
system, inhibit neutrophil elastase strongly while ecotin from the plant pathogen Pantoea citrea inhibits neutrophil elastase 1000-fold less potently. Ecotins...
2 KB (217 words) - 13:43, 21 June 2022
Presence of exocrine pancreatic insufficiency (according to monoclonal fecal elastase-1 or direct function tests). Pathological pancreatic imaging: (by endoscopic...
8 KB (746 words) - 15:42, 13 September 2024
Chymotrypsin-C (redirect from Elastase 4)
Chymotrypsin C, also known as caldecrin or elastase 4, is an enzyme that in humans is encoded by the CTRC gene. Chymotrypsin C is a member of the peptidase...
6 KB (695 words) - 01:22, 8 April 2022
proteoglycans (e.g. heparin and chondroitin), and proteolytic enzymes (e.g. elastase and lysophospholipase). They also secrete lipid mediators like leukotrienes...
15 KB (1,583 words) - 12:51, 22 June 2024
amount of elastase production and tissue invasion was first discovered in 1984. Clinical isolates have also been found to have greater elastase activity...
44 KB (4,593 words) - 21:58, 22 August 2024
breakdown of the connective tissue of the lungs by proteases (particularly elastase) that are insufficiently inhibited by protease inhibitors. The destruction...
159 KB (17,225 words) - 19:21, 1 October 2024
well as abundant neutrophils. One hypothesis for the cause is excessive elastase release from neutrophils and macrophages. It has also been considered that...
12 KB (1,176 words) - 12:51, 2 September 2024
(MMP-12) also known as macrophage metalloelastase (MME) or macrophage elastase (ME) is an enzyme that in humans is encoded by the MMP12 gene. Proteins...
10 KB (1,157 words) - 14:54, 26 August 2023
Chymotrypsin-like elastase family member 1 (CELA1) also known as elastase-1 (ELA1) is an enzyme that in humans is encoded by the CELA1 gene. Elastases form a subfamily...
5 KB (609 words) - 04:25, 18 September 2024
LTD4, LTE4) and prostaglandin (e.g., PGE2) families Enzymes, such as elastase Growth factors such as TGF beta, VEGF, and PDGF Cytokines such as IL-1...
29 KB (3,166 words) - 00:19, 9 September 2024