• Thumbnail for Elastase
    for elastase: Some bacteria (including Pseudomonas aeruginosa) also produce elastase. In bacteria, elastase is considered a virulence factor. Elastase breaks...
    6 KB (477 words) - 23:45, 3 February 2024
  • Thumbnail for Neutrophil elastase
    Neutrophil elastase (EC 3.4.21.37, leukocyte elastase, ELANE, ELA2, elastase 2, neutrophil, elaszym, serine elastase, subtype human leukocyte elastase (HLE))...
    9 KB (1,111 words) - 20:35, 7 May 2024
  • Pancreatic elastase is a form of elastase that is produced in the acinar cells of the pancreas, initially produced as an inactive zymogen and later activated...
    15 KB (1,794 words) - 01:00, 18 July 2024
  • Thumbnail for CELA3B
    CELA3B (redirect from Fecal elastase)
    Chymotrypsin-like elastase family member 3B also known as elastase-3B, protease E, or fecal elastase is an enzyme that in humans is encoded by the CELA3B...
    7 KB (889 words) - 07:25, 6 January 2024
  • Thumbnail for Alpha-1 antitrypsin
    only binds to neutrophil elastase from inflammatory cells but also to elastase on the cell surface. In this latter role, elastase acts as a signaling molecule...
    33 KB (3,383 words) - 08:00, 21 August 2024
  • Thumbnail for Exocrine pancreatic insufficiency
    'moderate' EPI is when fecal elastase levels are <200 ug/g, whereas 'severe' EPI is considered to be when fecal elastase levels is <100 ug/g. The exocrine...
    29 KB (3,058 words) - 14:48, 20 September 2024
  • Thumbnail for Alpha-1 antitrypsin deficiency
    environmental dust. The underlying mechanism involves unblocked neutrophil elastase and buildup of abnormal A1AT in the liver. It is autosomal co-dominant...
    27 KB (2,883 words) - 23:15, 10 September 2024
  • Thumbnail for Serine protease
    their substrate specificity as either trypsin-like, chymotrypsin-like or elastase-like. Trypsin-like proteases cleave peptide bonds following a positively...
    22 KB (2,343 words) - 20:13, 29 August 2024
  • Thumbnail for Neutrophil
    parasites. In alpha 1-antitrypsin deficiency, the important neutrophil elastase is not adequately inhibited by alpha 1-antitrypsin, leading to excessive...
    53 KB (5,693 words) - 06:53, 24 September 2024
  • Pancreatic elastase II (EC 3.4.21.71, pancreatic elastase 2) is an enzyme. This enzyme catalyses the following chemical reaction Preferential cleavage:...
    1 KB (149 words) - 15:16, 26 August 2023
  • Macrophage elastase (EC 3.4.24.65, metalloelastase, human macrophage metalloelastase (HME), MMP-12) is an enzyme. This enzyme catalyses the following chemical...
    2 KB (200 words) - 14:49, 26 August 2023
  • Elaszym (redirect from Serine elastase)
    Elaszym may refer to one of two enzymes: Pancreatic elastase Neutrophil elastase This disambiguation page lists articles associated with the title Elaszym...
    109 bytes (43 words) - 09:59, 28 December 2019
  • Pseudolysin (EC 3.4.24.26, Pseudomonas elastase, Pseudomonas aeruginosa neutral metalloproteinase) is an enzyme. This enzyme catalyses the following chemical...
    2 KB (230 words) - 15:36, 26 August 2023
  • Thumbnail for N-Acetylglucosamine
    acid, it forms hyaluronan. GlcNAc has been reported to be an inhibitor of elastase release from human polymorphonuclear leukocytes (range 8–17% inhibition)...
    8 KB (570 words) - 21:44, 8 May 2024
  • Thumbnail for SERPINB1
    Leukocyte elastase inhibitor (LEI) also known as serpin B1 is a protein that in humans is encoded by the SERPINB1 gene. It is a member of the clade B serpins...
    9 KB (1,148 words) - 17:04, 26 July 2024
  • Thumbnail for Biliary atresia
    aflatoxin damaged liver cells and bile duct cells are removed by neutrophil elastase and by involvement of immune system mediators such as CCL-2 or MCP-1, tumor...
    25 KB (2,730 words) - 01:09, 29 September 2024
  • Azurophils may contain myeloperoxidase, phospholipase A2, acid hydrolases, elastase, defensins, neutral serine proteases, bactericidal permeability-increasing...
    3 KB (216 words) - 19:28, 5 December 2023
  • Thumbnail for Elafin
    protein that in humans is encoded by the PI3 gene. This gene encodes an elastase-specific protease inhibitor, which contains a WAP-type four-disulfide core...
    9 KB (1,033 words) - 02:02, 15 August 2024
  • Thumbnail for Protease
    Each family may contain many hundreds of related proteases (e.g. trypsin, elastase, thrombin and streptogrisin within the S1 family). Currently more than...
    26 KB (2,799 words) - 15:02, 30 June 2024
  • Littré. Smegma contains cathepsin B, lysozymes, chymotrypsin, neutrophil elastase and cytokines, which aid the immune system. According to Wright, the production...
    12 KB (1,214 words) - 20:18, 24 September 2024
  • Thumbnail for Ecotin
    system, inhibit neutrophil elastase strongly while ecotin from the plant pathogen Pantoea citrea inhibits neutrophil elastase 1000-fold less potently. Ecotins...
    2 KB (217 words) - 13:43, 21 June 2022
  • Presence of exocrine pancreatic insufficiency (according to monoclonal fecal elastase-1 or direct function tests). Pathological pancreatic imaging: (by endoscopic...
    8 KB (746 words) - 15:42, 13 September 2024
  • Thumbnail for Chymotrypsin-C
    Chymotrypsin-C (redirect from Elastase 4)
    Chymotrypsin C, also known as caldecrin or elastase 4, is an enzyme that in humans is encoded by the CTRC gene. Chymotrypsin C is a member of the peptidase...
    6 KB (695 words) - 01:22, 8 April 2022
  • Thumbnail for Basophil
    proteoglycans (e.g. heparin and chondroitin), and proteolytic enzymes (e.g. elastase and lysophospholipase). They also secrete lipid mediators like leukotrienes...
    15 KB (1,583 words) - 12:51, 22 June 2024
  • Thumbnail for Aspergillus fumigatus
    amount of elastase production and tissue invasion was first discovered in 1984. Clinical isolates have also been found to have greater elastase activity...
    44 KB (4,593 words) - 21:58, 22 August 2024
  • Thumbnail for Chronic obstructive pulmonary disease
    breakdown of the connective tissue of the lungs by proteases (particularly elastase) that are insufficiently inhibited by protease inhibitors. The destruction...
    159 KB (17,225 words) - 19:21, 1 October 2024
  • Thumbnail for Cutis laxa
    well as abundant neutrophils. One hypothesis for the cause is excessive elastase release from neutrophils and macrophages. It has also been considered that...
    12 KB (1,176 words) - 12:51, 2 September 2024
  • Thumbnail for Matrix metallopeptidase 12
    (MMP-12) also known as macrophage metalloelastase (MME) or macrophage elastase (ME) is an enzyme that in humans is encoded by the MMP12 gene. Proteins...
    10 KB (1,157 words) - 14:54, 26 August 2023
  • Thumbnail for CELA1
    Chymotrypsin-like elastase family member 1 (CELA1) also known as elastase-1 (ELA1) is an enzyme that in humans is encoded by the CELA1 gene. Elastases form a subfamily...
    5 KB (609 words) - 04:25, 18 September 2024
  • Thumbnail for Eosinophil
    LTD4, LTE4) and prostaglandin (e.g., PGE2) families Enzymes, such as elastase Growth factors such as TGF beta, VEGF, and PDGF Cytokines such as IL-1...
    29 KB (3,166 words) - 00:19, 9 September 2024