humans, the family includes Her1 (EGFR, ErbB1), Her2 (ErbB2), Her3 (ErbB3), and Her4 (ErbB4). The gene symbol, ErbB, is derived from the name of a viral...
24 KB (2,736 words) - 00:12, 28 November 2023
HER2 (redirect from ErbB-2 receptor)
tyrosine-protein kinase erbB-2 is a protein that normally resides in the membranes of cells and is encoded by the ERBB2 gene. ERBB is abbreviated from erythroblastic...
43 KB (4,651 words) - 13:41, 27 July 2024
Epidermal growth factor receptor (redirect from Oncogene proteins v-erbb)
of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/neu (ErbB-2), Her 3 (ErbB-3) and Her...
60 KB (6,879 words) - 14:26, 16 July 2024
ERBB3 (redirect from Receptor, erbb-3)
(EGFR/ERBB) family of receptor tyrosine kinases. The kinase-impaired ErbB3 is known to form active heterodimers with other members of the ErbB family...
24 KB (2,816 words) - 23:40, 12 September 2024
different RTK classes have been identified. RTK class I (EGF receptor family) (ErbB family) RTK class II (Insulin receptor family) RTK class III (PDGF receptor...
28 KB (3,078 words) - 07:46, 3 June 2024
Look up Erb, erb, or 'erb in Wiktionary, the free dictionary. Erb, ERB or ErB may refer to: Edgar Rice Burroughs (1875–1950), American author Erb of Gwent...
3 KB (374 words) - 16:04, 30 July 2024
Erb's palsy is a paralysis of the arm caused by injury to the upper group of the arm's main nerves, specifically the severing of the upper trunk C5–C6...
16 KB (2,002 words) - 19:48, 30 August 2024
all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through their displayed interaction with ERBB receptors, NRG1 isoforms...
32 KB (3,921 words) - 10:13, 27 March 2024
dissertation focused on mechanisms of resistance to antibody-drug conjugates in ErbB receptors and it won her the university's Outstanding Doctorate Award the...
9 KB (674 words) - 21:05, 6 September 2024
wild-type EGFR that are expected to lead to a wider therapeutic index. The pan-ErbB inhibitor Neratinib was approved in the US in 2017 and in the EU in 2018...
20 KB (2,061 words) - 05:47, 29 November 2023
EJ (July 2002). "Role of the N-terminus of epidermal growth factor in ErbB-2/ErbB-3 binding studied by phage display". Biochemistry. 41 (27): 8732–41....
17 KB (1,708 words) - 13:56, 21 July 2024
the epidermal growth factor receptor (also known as EGF receptor, EGFR, ErbB-1 and HER1 in humans). Panitumumab is manufactured by Amgen and was originally...
16 KB (1,421 words) - 15:40, 14 July 2024
pp. 251–252. Keene D, Johnston D, Strother D, Fryer C, Carret AS, Crooks B, et al. (May 2007). "Epidemiological survey of central nervous system germ...
9 KB (984 words) - 06:12, 26 December 2021
PMID 20152769. Bánkfalvi A (November 2000). "Comparative methodological analysis of erbB-2/HER-2 gene dosage, chromosomal copy number and protein overexpression in...
10 KB (1,365 words) - 02:06, 17 June 2024
signaling is stronger and longer acting compared to heterodimers between other ERBB members. It has been reported that Trastuzumab induces the formation of...
69 KB (6,048 words) - 05:15, 1 October 2024
general, they bind to and activate the erbB family of receptor tyrosine kinases (erbB2 (HER2), erbB3 (HER3), and erbB4 (HER4)), functioning both as heterodimers...
8 KB (867 words) - 15:29, 1 January 2024
is a member of a family of receptors (ErbB) which includes Her1(EGFR), Her2(erb-B2), Her3(erb-B3) and Her4 (Erb-B4). EGFR is overexpressed in the cells...
21 KB (2,162 words) - 15:09, 19 August 2024
Lipid raft (section B-cell antigen receptor signaling)
"Lipid rafts and the local density of ErbB proteins influence the biological role of homo- and heteroassociations of ErbB2". Journal of Cell Science. 115 (22):...
57 KB (6,661 words) - 09:44, 6 October 2024
inhibition in the treatment of breast cancer: initial experience with the EGFR/ErbB-2 inhibitor lapatinib". The Oncologist. 9 (Suppl 3): 10–15. doi:10.1634/theoncologist...
17 KB (1,479 words) - 09:07, 5 September 2024
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) FGF HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators:...
7 KB (492 words) - 08:38, 3 October 2024
protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus"...
30 KB (3,445 words) - 13:46, 19 August 2024
Schulze WX, Deng L, Mann M (2005). "Phosphotyrosine interactome of the ErbB-receptor kinase family". Molecular Systems Biology. 1 (1): 2005.0008. doi:10...
24 KB (3,068 words) - 07:21, 7 June 2024
apoptotic cell death and PEA3-mediated transcriptional repression of Her2/neu (erbB-2) oncogene". Annals of Oncology. 16 (8): 1253–1267. doi:10.1093/annonc/mdi239...
39 KB (3,466 words) - 10:08, 22 May 2024
Index of biochemistry articles (section B)
epidiorite - epigenetics - epinephrine - equine gonadotropin - erbA gene - erbB gene - erbB-2 gene - erbB-2 receptor - erythropoietin - erythropoietin receptor...
29 KB (2,471 words) - 04:50, 19 January 2024
medication used for the treatment of multiple myeloma. Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. Elranatamab is...
12 KB (808 words) - 05:25, 15 September 2024
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) FGF HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators:...
17 KB (1,559 words) - 21:20, 27 September 2024
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) FGF HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators:...
11 KB (934 words) - 14:21, 19 September 2024
28 December 2016. "domain-b.com : Eli Lilly to buy Boehringer Ingelheim's US pet vaccines business for $885 mn". www.domain-b.com. "Elanco Animal Health...
40 KB (3,324 words) - 23:21, 18 September 2024
Hamburger AW (February 2000). "Interaction of the PA2G4 (EBP1) protein with ErbB-3 and regulation of this binding by heregulin". British Journal of Cancer...
10 KB (1,255 words) - 02:03, 8 April 2024