protein 2 also known as FHL-2 is a protein that in humans is encoded by the FHL2 gene. LIM proteins contain a highly conserved double zinc finger motif called...
39 KB (5,044 words) - 06:11, 25 July 2024
lymphoproliferative diseases and termed EBV+ HLH. Five genetic subtypes (FHL1, FHL2, FHL3, FHL4, and FHL5) are described, with an estimated overall prevalence...
29 KB (3,295 words) - 09:07, 13 June 2024
enhancing BMP signaling. FHL3 has been shown to interact with: CREB1, CTBP2, FHL2, ITGA7 and KLF3. GRCh38: Ensembl release 89: ENSG00000183386 – Ensembl, May...
9 KB (1,133 words) - 16:15, 13 November 2023
associated with egg-spot patterning and color arrangement. These are fhl2-a and fhl2-b, which are paralogs. These genes aid in pattern formation and cell-fate...
102 KB (9,847 words) - 13:21, 8 July 2024
Zhong H, Lu Q, Huang C, Ye Q (October 2003). "BRCA1 interacts with FHL2 and enhances FHL2 transactivation function". FEBS Lett. 553 (1–2): 183–9. Bibcode:2003FEBSL...
121 KB (13,581 words) - 14:59, 8 August 2024
autoimmune disease spondyloarthritis. CD18 has been shown to interact with: FHL2, GNB2L1, ICAM-1, and PSCD1. leukocyte adhesion deficiency integrin GRCh38:...
11 KB (1,299 words) - 10:15, 11 December 2023
gravis. Titin has been shown to interact with: ANK1, ANKRD1, ANKRD23 CAPN3, FHL2, OBSCN, TCAP, and TRIM63. The name titin is derived from the Greek Titan...
45 KB (4,650 words) - 10:29, 24 August 2024
galactoprotein b3 ('GAPB3'). CD49c has been shown to interact with: CD9 FHL2, LGALS8, and TSPAN4. GRCh38: Ensembl release 89: ENSG00000005884 – Ensembl...
5 KB (662 words) - 05:18, 30 January 2023
Isele U, Metzger E, Rempel A, Moser M, Pscherer A, et al. (February 2000). "FHL2, a novel tissue-specific coactivator of the androgen receptor". The EMBO...
87 KB (9,376 words) - 13:18, 19 August 2024
cerebral dopamine neurotrophic factor CEFIP: encoding protein Cardiac-enriched FHL2-interacting protein COMMD3-BMI1: COMMD3-BMI1 readthrough CPXM2: encoding...
28 KB (1,967 words) - 02:02, 11 April 2024
HGNC:16492 Q86V87 5674 FHIT HGNC:3701 P49789 5675 FHL1 HGNC:3702 Q13642 5676 FHL2 HGNC:3703 Q14192 5677 FHL3 HGNC:3704 Q13643 5678 FHL5 HGNC:17371 Q5TD97 5679...
277 KB (17 words) - 15:46, 9 May 2024
CBY1, CDH1, CDH2, CDH3, CDK5R1, CHUK, CTNND1, CTNNA1, EGFR, Emerin ESR1 FHL2, GSK3B, HER2/neu, HNF4A, IKK2, LEF1 including transgenically, MAGI1, MUC1...
107 KB (12,362 words) - 22:48, 10 July 2024
Cardiac-enriched FHL2-interacting protein (CEFIP) is a protein encoded by the gene C10orf71 on chromosome 10 open reading frame 71. It is primarily understood...
25 KB (1,678 words) - 10:08, 11 August 2024
variants has not been determined. ZNF638 has been shown to interact with FHL2. GRCh38: Ensembl release 89: ENSG00000075292 – Ensembl, May 2017 GRCm38:...
6 KB (799 words) - 16:53, 30 March 2022
PSEN2 has been shown to interact with: BCL2-like 1, CAPN1, CIB1, Calsenilin, FHL2, FLNB, KCNIP4, Nicastrin, and UBQLN1. GRCh38: Ensembl release 89: ENSG00000143801...
9 KB (1,100 words) - 16:13, 15 August 2024
lower mRNA levels. CD29 has been shown to interact with ACTN1; CD46, CD9, FHL2, Filamin, FLNB, CD81, GNB2L1, ITGB1BP1, LGALS8, MAP4K4, NME1, PKC alpha,...
22 KB (2,600 words) - 22:18, 2 April 2024
into the cytoplasm of the cell. EpICD forms a complex with the proteins FHL2, β-catenin, and Lef inside the nucleus. This complex then binds to DNA and...
20 KB (2,451 words) - 12:05, 4 April 2024
proteins have been reported. TRAF6 has been shown to interact with: ASK1, CD40, FHL2, HSPB2, IKBKG, IRAK1, IRAK2, TAB1, MAP3K7IP2, MAP3K7 PPP4C, RANK, SDCBP,...
20 KB (2,322 words) - 04:08, 22 December 2023
structures, bound to the four and one half LIM domain proteins, FHL1 and FHL2. It has been demonstrated that alpha-7 integrin can be mono-ADP-ribosylated...
26 KB (3,169 words) - 03:34, 10 March 2024
MAPK1 has been shown to interact with: ADAM17, CIITA, DUSP1, DUSP3, ELK1, FHL2, HDAC4, MAP2K1, MAP3K1 MAPK14, MKNK1, MKNK2, Myc, NEK2, PEA15, PTPN7,...
20 KB (2,283 words) - 00:38, 15 June 2024
inflammation or emphysema. Integrin beta 6 has been shown to interact with FHL2. GRCh38: Ensembl release 89: ENSG00000115221 – Ensembl, May 2017 GRCm38:...
35 KB (4,041 words) - 17:11, 23 December 2023
cytoplasm localization and is ubiquitously expressed Fanconi anemia disease FHL2 Four and a half LIM domains protein 2 Two hybrid prey Localized in the cytoplasm...
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regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2". Molecular and Cellular Biology. 24 (22): 9835–47. doi:10.1128/MCB.24.22...
18 KB (2,187 words) - 04:16, 1 July 2022
Carlile G, Licht JD, Schäfer BW (October 2002). "The LIM-only protein DRAL/FHL2 interacts with and is a corepressor for the promyelocytic leukemia zinc finger...
27 KB (3,374 words) - 10:55, 15 July 2024
CREB CREB1 has been shown to interact with: CEBPB, CREB binding protein, FHL2, FHL3, FHL5. HTATIP, P53, and RPS6KA5. GRCh38: Ensembl release 89: ENSG00000118260...
11 KB (1,259 words) - 01:22, 16 December 2023
Gertler F, Schüle R, Vingron M, Nordheim A (2004). "The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF". Mol. Cell. 16 (6): 867–80...
7 KB (957 words) - 22:51, 3 March 2023
Wixler V, Geerts D, Laplantine E, et al. (2000). "The LIM-only protein DRAL/FHL2 binds to the cytoplasmic domain of several alpha and beta integrin chains...
8 KB (1,093 words) - 13:00, 20 July 2024
dilated cardiomyopathy, two of which result in altered binding with TLN1 and FHL2. Mutations in ANKRD1 have also been associated with hypertrophic cardiomyopathy...
34 KB (4,294 words) - 03:02, 6 May 2024
element-dependent gene transcription by four-and-a-half LIM domains (FHL) 1, but not FHL2 or FHL3". Small GTPases. 10 (5): 361–366. doi:10.1080/21541248.2017.1327838...
9 KB (1,151 words) - 00:06, 28 July 2024
epithelia, while low level in muscle. EIF6 has been shown to interact with FHL2, ITGB4 and GNB2L1. EIF6 plays important roles in 80S ribosome formation,...
14 KB (1,816 words) - 01:32, 29 March 2024