The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of...
8 KB (827 words) - 22:08, 3 December 2023
fibroblast growth factor receptors (FGFRs). FGF1 is also known as acidic fibroblast growth factor, and FGF2 is also known as basic fibroblast growth factor...
25 KB (3,123 words) - 20:10, 26 April 2024
Fibroblast growth factor receptor 3 (FGFR-3) is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster...
17 KB (1,847 words) - 09:39, 15 July 2024
Fibroblast growth factor receptor 2 (FGFR-2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is encoded by the FGFR2...
14 KB (1,745 words) - 09:02, 15 July 2024
Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
44 KB (5,003 words) - 08:59, 15 July 2024
via specific fibroblast growth factor receptor (FGFR) proteins, themselves a family of closely related molecules. Fibroblast growth factor protein was...
22 KB (2,698 words) - 17:05, 16 July 2024
Fibroblast growth factor 1 (FGF-1) also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1...
20 KB (2,311 words) - 22:01, 16 July 2024
Fibroblast growth factor receptor 4 (FGFR-4) is a protein that in humans is encoded by the FGFR4 gene. FGFR4 has also been designated as CD334 (cluster...
10 KB (1,291 words) - 09:08, 15 July 2024
Fibroblast growth factor 23 (FGF-23) is a protein and member of the fibroblast growth factor (FGF) family which participates in the regulation of phosphate...
17 KB (1,856 words) - 18:26, 14 July 2024
Fibroblast growth factor 21 (FGF-21) is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast...
24 KB (3,038 words) - 18:36, 14 July 2024
Fibroblast growth factor 5(FGF5) Fibroblast growth factor 6(FGF6) Fibroblast growth factor 7(FGF7) Fibroblast growth factor 8(FGF8) Fibroblast growth...
10 KB (1,131 words) - 19:14, 31 March 2024
Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90...
28 KB (3,078 words) - 07:46, 3 June 2024
Fibroblast growth factor receptor-like 1 is a protein that in humans is encoded by the FGFRL1 gene. The protein encoded by this gene is a member of the...
6 KB (842 words) - 01:10, 27 January 2024
Fibroblast growth factor 8 (FGF-8) is a protein that in humans is encoded by the FGF8 gene. The protein encoded by this gene is a member of the fibroblast...
17 KB (2,175 words) - 03:31, 24 December 2023
epithelium. KGF is a small signaling molecule that binds to fibroblast growth factor receptor 2b (FGFR2b). For signalling to occur, a dimer is required...
2 KB (182 words) - 00:56, 11 June 2023
cell culture system, rat kidney fibroblasts. Application of the transforming growth factors to normal rat kidney fibroblasts induces the cultured cells to...
6 KB (596 words) - 05:15, 1 January 2024
epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
60 KB (6,879 words) - 14:26, 16 July 2024
FGF5 (redirect from Fibroblast growth factor 5)
Fibroblast growth factor 5 is a protein that in humans is encoded by the FGF5 gene. The majority of FGF family members are glycosaminoglycan binding proteins...
19 KB (2,251 words) - 15:12, 25 April 2024
Pfeiffer syndrome (category Cell surface receptor deficiencies)
big toes. Pfeiffer syndrome is caused by mutations in the fibroblast growth factor receptors FGFR1 and FGFR2. The syndrome is grouped into three types:...
14 KB (1,444 words) - 13:44, 3 July 2024
FGF18 (redirect from Fibroblast growth factor 18)
induce neurite outgrowth in PC12 cells. FGF18 signals through fibroblast growth factor receptor (FGFR) family, preferentially binding FGFR 3c (followed by...
20 KB (2,154 words) - 17:29, 16 July 2024
FRS3 (redirect from Fibroblast growth factor receptor substrate 3)
Fibroblast growth factor receptor substrate 3 is a protein that in humans is encoded by the FRS3 gene. The protein encoded by this gene is a substrate...
6 KB (734 words) - 05:08, 29 December 2023
enzymatic activity include: Receptor tyrosine kinase, as in fibroblast growth factor receptor. Most enzyme-linked receptors are of this type. Serine/threonine-specific...
7 KB (350 words) - 19:02, 13 March 2024
Paracrine signaling (redirect from Paracrine factor)
fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates...
46 KB (4,967 words) - 21:12, 7 July 2024
Sprifermin (redirect from Recombinant human fibroblast growth factor 18)
treatment of osteoarthritis. FGF18 and sprifermin act via the Fibroblast Growth Factor Receptor (FGFR) family, with preferential activity via FGFR3c. In 2020...
10 KB (532 words) - 01:58, 22 July 2024
Activation of other growth factor receptors such as fibroblast growth factor receptors or epidermal growth factor receptor can also be responsible. Acanthosis...
18 KB (1,782 words) - 19:54, 17 July 2024
is known as mechano-growth factor (MGF). Laron syndrome (LS), also known as growth hormone insensitivity or growth hormone receptor deficiency (GHRD),...
35 KB (4,573 words) - 03:04, 5 August 2024
targeting vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Ofev was developed by Boehringer...
34 KB (3,021 words) - 12:39, 5 August 2024
Fibroblast growth factor 19 is a protein that in humans is encoded by the FGF19 gene. It functions as a hormone, regulating bile acid synthesis, with effects...
21 KB (2,570 words) - 20:54, 5 June 2024
Pemigatinib (category Receptor tyrosine kinase inhibitors)
receptors (targets) called fibroblast growth factor receptors (FGFRs). FGFRs are found on the surface of cancer cells and are involved in the growth and...
19 KB (1,499 words) - 06:03, 16 July 2024
Fibroblast growth factor 10 is a protein that in humans is encoded by the FGF10 gene. The protein encoded by this gene is a member of the fibroblast growth...
11 KB (1,338 words) - 10:26, 25 April 2024