Fusion proteins or chimeric (kī-ˈmir-ik) proteins (literally, made of parts from different sources) are proteins created through the joining of two or...
19 KB (2,305 words) - 05:22, 15 May 2024
Respiratory syncytial virus (redirect from RSV fusion (F) protein)
protein also alters host immune response by inhibiting signaling from several toll-like receptors, including TLR4. Surface protein F (fusion protein)...
98 KB (9,900 words) - 16:33, 21 July 2024
Membrane fusion proteins (not to be confused with chimeric or fusion proteins) are proteins that cause fusion of biological membranes. Membrane fusion is critical...
11 KB (1,132 words) - 05:51, 6 May 2024
membrane fusion proteins. An example of a Class III viral fusion protein is the rabies virus glycoprotein, G. Class IV: Class IV viral fusion proteins are...
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Philadelphia chromosome (redirect from Bcr-abl fusion protein)
gene encodes for a BCR-ABL1 fusion protein. Depending on the precise location of fusion, the molecular weight of this protein can range from 185 to 210...
29 KB (3,538 words) - 15:01, 5 December 2023
Viral envelope (redirect from Viral envelope protein)
proteins. The membrane fusion event that triggers viral entrance is caused by the viral fusion protein. Many enveloped viruses only have one protein visible...
15 KB (1,972 words) - 13:47, 24 January 2024
fusing the viral and cellular membranes. Spike glycoprotein is a class I fusion protein that contains two regions, known as S1 and S2, responsible for these...
76 KB (7,457 words) - 08:55, 7 September 2024
Affinity chromatography (section Recombinant proteins)
against a GST-fusion protein it will produce antibodies against the fusion-protein, and possibly antibodies against the GST tag as well. The protein can then...
29 KB (3,430 words) - 03:30, 24 June 2024
Coronaviruses exhibit coronavirus spike protein, also known as the S protein, on their surfaces; S is a class I fusion protein and is responsible for mediating...
11 KB (1,091 words) - 15:33, 5 September 2024
cells. For example, by creating a fusion gene of a protein of interest and green fluorescent protein, the protein of interest may be observed in cells...
17 KB (1,928 words) - 19:40, 5 August 2024
purification of recombinant proteins. The fusion protein binds to amylose columns while all other proteins flow through. The MBP-protein fusion can be purified by...
19 KB (2,397 words) - 23:52, 7 November 2023
Next in the cycle is the fusion of the viral and host membranes which is likely mediated by the F protein. Though the fusion mechanism is very similar...
37 KB (4,348 words) - 14:54, 8 August 2024
transcription of the fusion protein, resulting in excessive pro-proliferative or anti-apoptotic effects on the B cells containing the fusion protein.[citation needed]...
11 KB (977 words) - 12:47, 19 February 2023
SNARE proteins is to mediate the fusion of vesicles with the target membrane; this notably mediates exocytosis, but can also mediate the fusion of vesicles...
53 KB (6,566 words) - 03:25, 8 July 2024
allows the fusion protein to access and activate micro-satellite regions of the genome that would otherwise be inaccessible. This fusion protein can convert...
41 KB (4,430 words) - 13:45, 10 May 2024
Two-hybrid screening (category Protein–protein interaction assays)
non-fusion protein may be co-expressed with two fusion proteins. Depending on the investigation, the third protein may modify one of the fusion proteins or...
47 KB (6,112 words) - 03:07, 1 April 2024
sensitive fusion proteins, is an enzyme which in humans is encoded by the NSF gene. NSF is a homohexameric AAA ATPase involved in membrane fusion. NSF is...
14 KB (1,747 words) - 19:21, 13 August 2023
of nuclei. The work conducted by Henry and Nils showed that proteins from one gene fusion affect gene expression in the other partner's nucleus, and vice...
16 KB (2,000 words) - 19:16, 12 August 2024
the entry of pathogens can be governed by fusion, as many bilayer-coated viruses have dedicated fusion proteins to gain entry into the host cell. There...
29 KB (3,384 words) - 11:35, 22 December 2023
chromosomes, one of each pair "sticks" and blends together homogeneously. A gene fusion may be created when the translocation joins two otherwise-separated genes...
19 KB (1,523 words) - 17:16, 1 August 2024
notable exceptions due to a unique set of proteins known as fusion-associated small transmembrane (FAST) proteins. Reovirus induced syncytium formation is...
18 KB (2,046 words) - 03:47, 22 August 2024
Etanercept (category Recombinant proteins)
potential to treat these diseases by inhibiting TNF-alpha. Etanercept is a fusion protein produced by recombinant DNA. It fuses the TNF receptor to the constant...
33 KB (2,917 words) - 16:32, 16 July 2024
fusion protein has been expressed, there is a wide range of potential areas of experimentation including enzymatic assays, cellular imaging, protein arrays...
9 KB (977 words) - 10:34, 27 December 2023
Oncogene (redirect from Fusion oncogene protein)
translocation events that lead to a fusion between a proto-oncogene and a 2nd gene (this creates a fusion protein with increased cancerous/oncogenic activity)...
28 KB (3,173 words) - 16:31, 16 August 2024
(2019). "In Silico Design and Immunologic Evaluation of HIV-1 p24-Nef Fusion Protein to Approach a Therapeutic Vaccine Candidate". Current HIV Research....
13 KB (1,457 words) - 17:30, 5 September 2024
Hemagglutinin (influenza) (category Viral structural proteins)
Hemagglutinin is a Class I Fusion Protein, having multifunctional activity as both an attachment factor and membrane fusion protein. Therefore, HA is responsible...
27 KB (3,152 words) - 20:26, 12 May 2024
Factor IX (redirect from Coagulation factor IX, albumin fusion protein)
IX [recombinant] (Idelvion) coagulation factor IX (recombinant), Fc fusion protein (Alprolix) coagulation factor IX [recombinant] (Ixinity) coagulation...
34 KB (1,977 words) - 02:49, 19 August 2024
for it to inhibit transcription. The protein's C-terminus contains the C-terminus of the TrkC. The fusion protein lacks transcription regulating activity...
16 KB (1,955 words) - 01:29, 20 August 2023
writes new genetic information into a targeted DNA site. It uses a fusion protein, consisting of a catalytically impaired Cas9 endonuclease fused to an...
26 KB (3,050 words) - 04:06, 9 August 2024
His-tag (redirect from Polyhistidine fusion protein)
acid motif in proteins that typically consists of at least six histidine (His) residues, often at the N- or C-terminus of the protein. It is also known...
22 KB (2,655 words) - 07:35, 10 August 2024