In molecular biology, G-quadruplex secondary structures (G4) are formed in nucleic acids by sequences that are rich in guanine. They are helical in shape...

normally located at the telomeres (the ends of the chromosomes). The G-quadruplex can either be parallel or antiparallel depending on the loop configuration...

pairs are observed in alternative structures such as the four-stranded G-quadruplex structures that form in DNA and RNA. Hoogsteen pairs have quite different...

Look up quadruplex in Wiktionary, the free dictionary. Quadruplex may refer to: Quadruplex (New Orleans), a softball complex in New Orleans City Park Quadruplex...

intercalated-motif DNA, are cytosine-rich four-stranded quadruplex DNA structures, similar to the G-quadruplex structures that are formed in guanine-rich regions...

classes of cruciform DNA have been described; folded and unfolded. G-quadruplex G-quadruplex secondary structures (G4) are formed in nucleic acids by sequences...

needed] There are also triple-stranded DNA forms and quadruplex forms such as the G-quadruplex and the i-motif. Twin helical strands form the DNA backbone...

Anti-thrombin aptamers are G-quadruplex-bearing oligonucleotides, which recognizes the exosites of human thrombin. The first anti-thrombin aptamer, TBA...

with two helical strands and an internal bulge with a G-quadruplex motif. It is at this G-quadruplex that the fluorophore binds. Based on crystallographic...

of the C-terminal region. RHAU exhibits a unique ATP-dependent guanine-quadruplex (G4) resolvase activity and specificity for its substrate in vitro. RHAU...

four guanine residues form a near planar base quartet, referred to as G-quadruplex, where each guanine participates in base pairing with its neighboring...

form a quadruplex in RNA by Hoogsteen hydrogen bonds to form a “Hoogsteen ring” (See Figure). G-C and A-U pairs can also form base quadruplex with a combination...

18.7049. PMC 297991. PMID 2780561. Lipps HJ, Rhodes D (August 2009). "G-quadruplex structures: in vivo evidence and function". Trends in Cell Biology. 19...

miRNA:miRNA* pairing also affects cleavage. Some of the G-rich pre-miRNAs can potentially adopt the G-quadruplex structure as an alternative to the canonical hairpin...

enantioselectivity were related to the DNA sequence. The hemin/G-Quadruplex DNAzyme consists of G-Quadruplex forming DNA that can bind the co-factor hemin (a.k.a...

flat four-base units then stack on top of each other to form a stable G-quadruplex structure. These structures are stabilized by hydrogen bonding between...

indicates that several genes (including the proto-oncogene c-myc) have G-quadruplex motifs as potential regulatory signals. Promoters are important gene...

Lin & Chun-Ting Zhang (2008). "Greglist: a database listing potential G-quadruplex regulated genes". Nucleic Acids Res. 36 (suppl 1) (Database issue): D372...

Pontiac G4, a compact car sold in Mexico G4 EA H1N1, a strain of influenza G-quadruplex, a DNA secondary structure Group 4 element, a class of elements on the...

PMID 12515382. Braun JE, Truffault V, Boland A, Huntzinger E, Chang CT, Haas G, Weichenrieder O, Coles M, Izaurralde E (December 2012). "A direct interaction...

apparent affinity for the G-quadruplex structure. They appear to modulate alternative splicing via the interaction with the G-quadruplex RNA-forming structure...

the structure. Usually, there are at least two guanine tetrads in a G-quadruplex, and they often feature Hoogsteen-style hydrogen bonding. Guanine tetrads...

8-oxo-dG is formed in a guanine rich, potential G-quadruplex-forming sequence (PQS) in the coding strand of a promoter, active OGG1 excises the 8-oxo-dG and...

Telomestatin induces the formation of basket-type G-quadruplex (G4) structures from hybrid-type G-quadruplexes in the telomeric region. Upon formation...

quadruplex of guanine-rich DNA structures that may be involved in cancers. 3D Molecular Structure of the intramolecular human telomeric G-quadruplex in...

N, Choinard S, Lemhemdi A, Macaisne N, Van Leene J, Gevaert K, De Jaeger G, Chelysheva L, Mercier R (2015). "Multiple mechanisms limit meiotic crossovers:...

binding mode to G-quadruplex DNA upon exposure to visible light. This method could potentially modulate the activity of G-quadruplex DNA, crucial in gene...

microsatellites lead to the formation of secondary DNA structures (e.g. G-quadruplex) and rely on WRN to repair these bulky lesions. Because of this therapeutic...

Villar-Guerra, Rafael; Trent, John O.; Chaires, Jonathan B. (2018). "G-Quadruplex Secondary Structure Obtained from Circular Dichroism Spectroscopy". Angewandte...

delivery vehicles, hydro- and organogels, molecular bioanalytic sensors, G-quadruplex DNA binding molecular therapeutics, and biologically active natural product...