• Thumbnail for Hirudin
    Hirudin is a naturally occurring peptide in the salivary glands of blood-sucking leeches (such as Hirudo medicinalis) that has a blood anticoagulant property...
    7 KB (818 words) - 22:18, 26 June 2024
  • Hirudin (stylized as HiRUDiN) is the fourth studio album by Canadian electronic music band Austra, released on May 1, 2020, by Domino worldwide and by...
    5 KB (215 words) - 12:03, 26 May 2022
  • Thumbnail for Hirudo medicinalis
    piercing the skin, they suck out blood while injecting anticoagulants (hirudin). Large adults can consume up to ten times their body weight in a single...
    18 KB (1,947 words) - 10:55, 16 August 2024
  • Thumbnail for Leech
    with a sucker and feeding on blood, having first secreted the peptide hirudin to prevent the blood from clotting. The jaws used to pierce the skin are...
    55 KB (5,782 words) - 16:41, 3 July 2024
  • Thumbnail for Austra (band)
    albums—Feel It Break (2011), Olympia (2013), Future Politics (2017), and Hirudin (2020). In 2004, Stelmanis and Postepski played in a band called Galaxy...
    18 KB (1,262 words) - 02:54, 3 September 2024
  • Thumbnail for Hematophagy
    substances in the saliva of several hematophagous species, such as leeches (hirudin). Hematophagy is classified as either obligatory or facultative. Obligatory...
    12 KB (1,345 words) - 21:32, 29 May 2024
  • injection. Lepirudin is a recombinant hirudin derived from yeast cells. Lepirudin is almost identical to hirudin extracted from Hirudo medicinalis, having...
    5 KB (338 words) - 02:57, 5 October 2023
  • recently, is the allosteric inhibitors. Hirudin and derivatives were originally discovered in Hirudo medicinalis: Hirudin Bivalirudin (transient inhibition...
    7 KB (821 words) - 09:44, 30 January 2023
  • technological advances in genetic engineering the production of recombinant hirudin was made possible which opened the door to this new group of drugs. Before...
    33 KB (3,756 words) - 17:07, 14 December 2023
  • Thumbnail for Ecarin clotting time
    laboratory test used to monitor anticoagulation during treatment with hirudin, an anticoagulant medication which was originally isolated from leech saliva...
    3 KB (327 words) - 22:51, 21 April 2022
  • the reptilase time is not prolonged in blood samples containing heparin, hirudin, or direct thrombin inhibitors, whereas the thrombin time will be prolonged...
    2 KB (189 words) - 06:33, 14 December 2023
  • Thumbnail for Echis carinatus
    (ECT) test, which is used to monitor anticoagulation during treatment with hirudin. Yet another drug produced from E. carinatus venom is Aggrastat (Tirofiban)...
    26 KB (2,342 words) - 04:50, 3 May 2024
  • Thumbnail for Tooth
    inside of a circle. After piercing the skin and injecting anticoagulants (hirudin) and anaesthetics, they suck out blood, consuming up to ten times their...
    42 KB (5,021 words) - 05:16, 26 August 2024
  • paved way for the first successful synthetic anticoagulants including hirudin. The monitoring of warfarin and keeping the international normalized ratio...
    16 KB (1,525 words) - 03:57, 3 February 2024
  • Thumbnail for Drug discovery
    based on compounds found in animals. For example, the anticoagulant drugs, hirudin and its synthetic congener, bivalirudin, are based on saliva chemistry...
    58 KB (6,739 words) - 11:28, 24 July 2024
  • Thumbnail for Injection (medicine)
    and itching reaction. Leeches can inject an anticoagulant peptide called hirudin after attaching to prevent blood from clotting during feeding. This property...
    48 KB (5,650 words) - 16:49, 5 May 2024
  • Thumbnail for Bivalirudin
    Chemically, it is a synthetic congener of the naturally occurring drug hirudin, found in the saliva of the medicinal leech Hirudo medicinalis. It is manufactured...
    28 KB (2,792 words) - 20:16, 23 April 2024
  • the town of Giessen, Germany. The procedure lasted only 15 minutes, and hirudin served as the anticoagulant. Haas was able to develop a dialyzer consisting...
    3 KB (222 words) - 13:00, 13 February 2024
  • Thumbnail for Anticoagulant
    thrombin inhibitor. Current members of this class include the bivalent drugs hirudin, lepirudin, and bivalirudin and the monovalent drugs argatroban and dabigatran...
    78 KB (8,755 words) - 00:46, 23 July 2024
  • Thumbnail for Sucker (zoology)
    those six segments) to stay attached and secrete an anti-clotting enzyme, hirudin, into the host's blood stream. The medicinal leech (Hirudo medicinalis)...
    14 KB (1,563 words) - 23:31, 5 March 2024
  • Thumbnail for Mason Science College
    Haycraft, discovered an anticoagulant created by the leech, which he named hirudin John Rippiner Heath, physician and composer Micaiah John Muller Hill, FRS...
    17 KB (1,331 words) - 18:13, 19 August 2024
  • Genre Label Ref. May 1 American Aquarium Lamentations New West Austra Hirudin Electronic Domino Boston Manor Glue Alternative rock Pure Noise Caleb Landry...
    371 KB (18,978 words) - 07:00, 20 July 2024
  • Thumbnail for Haemadin
    to a superfamily (MEROPS IM) of protease inhibitors that also includes hirudin (MEROPS I14.001) and antistasin (MEROPS I15). Richardson JL, Kroger B,...
    2 KB (212 words) - 00:44, 15 May 2022
  • Thumbnail for Thrombin
    COMPLEXES OF HIRUDIN DERIVATIVES AND HUMAN ALPHA-THROMBIN DUE TO DIFFERENT CRYSTAL FORMS 1tmu: CHANGES IN INTERACTIONS IN COMPLEXES OF HIRUDIN DERIVATIVES...
    26 KB (2,932 words) - 19:37, 9 May 2024
  • "Yes Exactly" 2020 Kane West & Thomas Van Party — "Mountain Baby" Austra HiRUDiN "Anywayz" Co-writer "Show Me What" A. G. Cook 7G Featured artist "Wish...
    13 KB (841 words) - 23:13, 15 July 2024
  • Thumbnail for Robert Huber
    activation mechanism of this enzyme, and of the complex of thrombin with hirudin, which showed the molecular mechanism of inhibition of blood clotting by...
    14 KB (1,211 words) - 14:00, 20 August 2024
  • families are named with an I followed by a number, for example, I14 contains hirudin-like inhibitors. Classes of proteases are: Aspartic protease inhibitors...
    19 KB (1,811 words) - 01:19, 29 November 2023
  • Thumbnail for Protein S
    and C4b-binding protein levels in plasma anticoagulated with citrate or hirudin". Blood. 79 (12): 3203–11. doi:10.1182/blood.V79.12.3203.bloodjournal79123203...
    14 KB (1,777 words) - 17:34, 10 April 2024
  • Thumbnail for Multiple electrode aggregometry
    against time on the computer screen. The manufacturer recommends the use of hirudin as anticoagulant for samples to be tested, but studies have shown that...
    15 KB (1,754 words) - 21:11, 16 May 2024
  • Thumbnail for Anti-thrombin aptamers
    thrombin) is around 70 to 80 nmol/L, which is much lower than that of hirudin (~1.7 umol/L). Also, compared with heparin, TBA is more efficient in the...
    23 KB (2,660 words) - 05:35, 3 June 2024