also known as IRF3, is an interferon regulatory factor. IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 was originally...
12 KB (1,493 words) - 01:36, 11 December 2023
Stimulator of Interferon Genes (STING) which triggers phosphorylation of IRF3 via TBK1. IRF3 can then go to the nucleus to trigger transcription of inflammatory...
23 KB (2,886 words) - 15:56, 23 September 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
46 KB (4,655 words) - 20:47, 5 October 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
52 KB (5,499 words) - 18:00, 11 September 2024
It has been shown to activate downstream transcription factors STAT6 and IRF3 through TBK1, which are responsible for antiviral response and innate immune...
24 KB (2,748 words) - 06:07, 21 September 2024
regulatory factor 1 (IRF1), and interferon regulatory factor 3 (IRF3). NF-κB, IRF1, and IRF3 are transcription factors and play critical roles in the production...
16 KB (1,931 words) - 19:24, 19 August 2024
infection, and induces the activation of IRF3 and NF-κB. Unlike other TLRs, TLR3 uses TRIF as the sole adaptor. IRF3 ultimately induces the production of...
9 KB (1,027 words) - 06:24, 13 September 2024
IrCl3 iridium(III) chloride 10025–83–9 IrCl4 iridium(IV) chloride 10025–97–5 IrF3 iridium(III) fluoride 23370–59–4 IrF4 iridium(IV) fluoride 37501–24–9 IrF5...
139 KB (120 words) - 17:07, 15 July 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
12 KB (923 words) - 12:37, 7 September 2024
three immune system proteins. PLpro cleaves IRF3 and 3CLpro cleaves both NLRP12 and TAB1. "Direct cleavage of IRF3 by NSP3 could explain the blunted Type-I...
52 KB (5,899 words) - 06:01, 22 August 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
19 KB (1,848 words) - 16:23, 29 August 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
15 KB (1,376 words) - 17:03, 13 October 2024
interferons by suppressing the activity of the interferon regulatory proteins IRF3, IRF5 and IRF7. The levels of IgG and IgA in the blood and IgA in the gut...
86 KB (9,961 words) - 04:05, 4 September 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
7 KB (519 words) - 02:51, 10 April 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
47 KB (5,060 words) - 17:43, 5 October 2024
research has demonstrated that nsp12 inhibits the nuclear translocation of IRF3. The RNA-dependent RNA polymerase domain of nsp12 is C-terminal. In SARS-CoV-2...
10 KB (1,238 words) - 18:11, 20 July 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
12 KB (1,082 words) - 02:01, 24 September 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
13 KB (1,185 words) - 08:15, 14 October 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
21 KB (1,996 words) - 06:54, 27 August 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
22 KB (1,964 words) - 06:53, 26 September 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
3 KB (191 words) - 04:08, 31 May 2024
the innate immune signalling. Specifically, agnoprotein is known to impair IRF3 nuclear translocation and induce mitochondrial fragementation. Small T antigen...
23 KB (2,674 words) - 23:14, 12 October 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
42 KB (4,064 words) - 02:28, 9 September 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
15 KB (1,480 words) - 18:47, 11 September 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
11 KB (1,062 words) - 00:27, 14 October 2024
ENSG00000168310 IRF Known motif – High-throughput in vitro [427] GAAAVYGAAAS IRF3 ENSG00000126456 IRF Known motif – High-throughput in vitro [428] HSGAAAVBGAAACYGAAAC...
374 KB (81 words) - 02:10, 23 September 2023
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
25 KB (2,349 words) - 01:04, 23 September 2024
knockdown of WDR5 in order to see if it inhibited virus-triggered activation of IRF3 and NF-kappaB, as well as transcription of the IFNB1 gene, thereby lowering...
14 KB (1,526 words) - 02:25, 22 September 2024
HfF4 TaF5 WF4 WF5 WF6 ReF4 ReF5 ReF6 ReF7 OsF4 OsF5 OsF6 ?OsF 7 ?OsF 8 IrF2 IrF3 IrF4 IrF5 IrF6 PtF2 Pt[PtF6] PtF4 PtF5 PtF6 AuF AuF3 Au2F10 ?AuF6 AuF5•F2...
8 KB (656 words) - 05:43, 18 February 2024
After binding dsRNA, this receptor activates the transcription factors IRF3 and NF-κB, which are important for initiating synthesis of many inflammatory...
62 KB (7,065 words) - 05:17, 28 June 2024